[RuCl2(dppf)(PN)]/Pd-cocatalyzed three-component synthesis of 2-pyridinyl-6-arylquinolines

Hao Wang; Pengtao Bai; Shuo Wen; Jingjing Wei; Heng Song; Chen Xu

doi:10.1515/znb-2023-0018

Published by De Gruyter August 31, 2023

[RuCl₂(dppf)(PN)]/Pd-cocatalyzed three-component synthesis of 2-pyridinyl-6-arylquinolines

Hao Wang , Pengtao Bai , Shuo Wen , Jingjing Wei , Heng Song and Chen Xu

From the journal Zeitschrift für Naturforschung B

https://doi.org/10.1515/znb-2023-0018

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Abstract

A new complex [RuCl₂(dppf)(PN)] 1 (dppf = 1,1′-bis(diphenylphosphino) ferrocene; PN = (2-diphenylphosphino)benzenamine) has been synthesized and characterized. Its structure was determined by single-crystal X-ray diffraction. An efficient 1/Pd salt-cocatalyzed three-component oxidation/cyclization/Suzuki reaction for the synthesis of 2-pyridinyl-6-arylquinolines from 2-acetylpyridine, (2-amino-5-bromophenyl)methanol, and arylboronic acids has been developed.

Keywords: multicomponent reaction; quinoline; ruthenium complex; Suzuki reaction

Corresponding author: Chen Xu, School of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu 212100, P.R. China, E-mail: chenxu@just.edu.cn

Research ethics: Not applicable.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Competing interests: The authors declare no conflicts of interest regarding this article.
Research funding: The Natural Science Foundation of Jiangsu Province (No. 182300410230) and China Postdoctoral Science Foundation (2022M711401).
Data availability: Not applicable.

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Received: 2023-03-22

Accepted: 2023-07-30

Published Online: 2023-08-31

Published in Print: 2023-09-26

[RuCl₂(dppf)(PN)]/Pd-cocatalyzed three-component synthesis of 2-pyridinyl-6-arylquinolines

Abstract

References

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