Histol Histopathol

Review Open Access

Bioceramic versus traditional biomaterials for endodontic sealers according to the ideal properties

Miguel A. Ortega1,2,3, Laura Rios4, Oscar Fraile-Martinez1,2, Diego Liviu Boaru1, Diego De Leon-Oliva1, Silvestra Barrena-Blázquez1,2, Claude Pereda-Cerquella1, Maria J. Garrido-Gil1, Luis Manteca4, Julia Buján1,2, Natalio García-Honduvilla1,2, Cielo García-Montero1,2* and Antonio Rios-Parra1,2,3*

1Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcala de Henares, 2Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, 3Cancer Registry and Pathology Department, Principe de Asturias University Hospital, Alcala de Henares and 4Universidad San Pablo CEU, Madrid, Spain
*These authors contributed equality


Corresponding Author: Miguel A. Ortega and Cielo García-Montero, Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034, Madrid, Spain. e-mail: cielo.gmontero@gmail.com or miguel.angel.ortega92@gmail.com


Summary. Odontology, as a scientific discipline, continuously collaborates with biomaterials engineering to enhance treatment characteristics and patients' satisfaction. Endodontics, a specialized field of dentistry, focuses on the study, diagnosis, prevention, and treatment of dental disorders affecting the dental pulp, root, and surrounding tissues. A critical aspect of endodontic treatment involves the careful selection of an appropriate endodontic sealer for clinical use, as it significantly influences treatment outcomes. Traditional sealers, such as zinc oxide-eugenol, fatty acid, salicylate, epoxy resin, silicone, and methacrylate resin systems, have been extensively used for decades. However, advancements in endodontics have given rise to bioceramic-based sealers, offering improved properties and addressing new challenges in endodontic therapy. In this review, a classification of these materials and their ideal properties are presented to provide evidence-based guidance to clinicians. Physicochemical properties, including sealing ability, stability over time and space, as well as biological properties such as biocompatibility and antibacterial characteristics, along with cost-effectiveness, are essential factors influencing clinicians' decisions based on individual patient evaluations. Histol Histopathol 39, 279-292 (2024)

Key words: Endodontics, Bioceramic-based sealers, Traditional sealers, Biocompatibility, Setting time, Stability, Antibacterial properties

DOI: 10.14670/HH-18-664


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©The Author(s) 2024. Open Access. This article is licensed under a Creative Commons CC-BY International License.