Correction to: Metabolic Brain Disease (2022) 37:1057–1070

https://doi.org/10.1007/s11011-022-00937-2

The Fig. 4, Fig. 5, Fig. 6, Fig.7 and Fig. 8 in the article were not the final version, the final version Fig. 4, Fig. 5, Fig. 6, Fig.7 and Fig. 8 are shown below.

Fig. 4
figure 1

PF attenuated MPTP induced loss of nigrostriatal DA neurons in the PD mice. (A-B) DAB staining of TH on nigrostriatal of each group (Scale bar: 250 μm). (C) The counts of TH-positive cells of the SNpc. (D) Average optical density of the striatum of each group. (E-F) The expression level of TH proteins was detected with Western Blot in the Striatum, β-actin served as control. Statistical analysis was performed with One-Way ANOVA or Two-Way ANOVA, n = 3. Significant differences were indicated by * P < 0.05; ** P < 0.01; *** P < 0.001

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Fig. 5
figure 2

PF attenuated MPTP induced cell apoptosis in the PD mice. (A) TUNEL assay of the apoptotic neurons in the SNpc of mice. TUNEL (green), TH (red) and DAPI (blue), (Scale bar: 50 μm). (B) Apoptosis index of the SNpc in each group. (C-E) The expression level of the Bcl-2/Bax, Cl-casp3 protein were detected with Western Blot in the Striatum. β-actin served as control. Statistical analysis was performed with Two-Way ANOVA, n = 3. Significant differences were indicated by * P < 0.05, ** P < 0.01, *** P < 0.001

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Fig. 6
figure 3

Nissl staining was performed on sections from the hippocampus to determine neuronal survival. (A) Typical photomicrographs of Nissl staining of the hippocampal CA1 and CA3 in each group. (B) The apoptotic cells quantity was calculated in the CA1 region of the hippocampus. (C) The apoptotic cells quantity was calculated in the CA3 region of the hippocampus. (D-E) The expression level of the Bcl-2/Bax protein was detected with Western Blot in the Striatum. β-actin served as control. Statistical analysis was performed with One-Way ANOVA, Turkey’s multiple comparison test post hoc, n = 3. Significant differences were indicated by * P < 0.05, ** P < 0.01, *** P < 0.001

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Fig. 7
figure a

Detection of the accumulation of Aβ and the expression of synaptic-related proteins. (A) Immunofluorescent staining of Aβ (Red) and the DAPI (blue) in the CA1 and CA3 (scale bar = 20 μm). (B-C) Mean fluorescence intensity analysis for Aβ (n = 3, per group). (D-F) Expression of PSD-95, SYN were assessed by Western blot analysis. β-actin served as control. Statistical analysis was performed with One-Way ANOVA, Turkey’s multiple comparison test post hoc, n = 3. Significant differences were indicated by * P < 0.05, ** P < 0.01, *** P < 0.001

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Fig. 8
figure 4

Impact of PF on the phosphorylation of JNK/p53 pathway in MPTP-induced PD mice. (A-D) Expression of p-JNK/JNK, p-c-Jun/c-Jun and p-p53/p53 proteins were assessed by Western blot analysis. β-actin served as control. Statistical analysis was performed with One-Way ANOVA, Turkey’s multiple comparison test post hoc, n = 3. Significant differences were indicated by * P < 0.05, ** P < 0.01, *** P < 0.001

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