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Spectral Analysis of Heart Rate Variability Based on the Hilbert–Huang Method

  • BIOCHEMISTRY, BIOPHYSICS, AND MOLECULAR BIOLOGY
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Abstract

Analysis of heart rate variability (HRV) is widely used for noninvasive assessment of the state of the regulation systems of the heart. The aim of this study was to evaluate the capabilities of the Hilbert–Huang method for calculating spectral parameters of HRV in comparison with the commonly used Fourier analysis. Fourier analysis allows estimation of averaged spectral amplitudes and power of HRV oscillations in fixed frequency intervals, which are associated with the activity of sympathetic, parasympathetic, and humoral regulation systems. Using the Hilbert–Huang method, we revealed four spectral components, described by Gaussian functions, in which HRV oscillations are concentrated, and showed the absence of fixed boundaries between them. The obtained energy quantitative characteristics of the spectral components of heart rhythm oscillations can serve as the basis for diagnostic methods of heart rhythm regulation, supplementing the commonly used ones.

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ACKNOWLEDGMENTS

The authors are grateful to all the staff members of the  Institute of Cell Biophysics, Russian Academy of Sciences, who participated in the study as voluntary subjects. Our special thanks are due to Ph.D. A.V. Tankanag and Ph.D. I.V. Tikhonova for technical assistance in this study.

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Authors and Affiliations

  1. Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia

    A. A. Grinevich & N. K. Chemeris

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  1. A. A. Grinevich
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  2. N. K. Chemeris
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Correspondence to A. A. Grinevich or N. K. Chemeris.

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Conflict of interest. The authors declare that they have no conflicts of interest.

Statement of compliance with standards of research involving humans as subjects. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants involved in the study.

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Translated by M. Batrukova

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Grinevich, A.A., Chemeris, N.K. Spectral Analysis of Heart Rate Variability Based on the Hilbert–Huang Method. Dokl Biochem Biophys 511, 169–172 (2023). https://doi.org/10.1134/S1607672923700333

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  • DOI: https://doi.org/10.1134/S1607672923700333

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