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Investigation on the Design and Application of Hydraulic Loading Fatigue Test Device for Non-Vascular Stent

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Abstract

Background

The implanted non-vascular stent is prone to fatigue fracture due to the periodic cyclic load caused by long-term physiological motion in the non-vascular lumen.

Objective

To effectively study and predict the fatigue performance of non-vascular stents, an experimental setup was designed to simulate and conduct fatigue performance tests on non-vascular stents under various loads. This design simplified the periodic cyclic loads generated within non-vascular lumens, in accordance with the physiological motion patterns of non-vascular lumens, into pulsatile loads.

Methods

To meet the requirements of different stents and various fluctuating load conditions during testing, the relationship between test conditions and the fatigue load of the stent was studied based on Fluent.

Results

A fatigue test device with a special load module was built and used to complete the fatigue performance test of a group of esophageal stents. It can be found that the experimental device can satisfy the control and application of the fatigue load of the stent, and can effectively realize the testing requirements of the fatigue performance of the stent.

Conclusion

In this paper, a non-vascular stent fatigue in vitro test device that can simulate the fluctuating load of a non-vascular lumen is designed. The results of flow field simulation, fatigue simulation, and actual fatigue test show that the device can meet the needs of fatigue test and has good versatility and operability.

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Data Availability

The data underlying this article are available in the article and in its online supplementary material.

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Acknowledgements

This research was partially supported by the National Natural Science Foundation of China (Grant No: 51005124). The authors thank Dr. Weiyu Chen, Dr. Yunfeng Gu, and Dr. Dong Jiang from the Department of Mechanics of Nanjing Forestry University for the helpful guidance provided in building the test device and writing the article. The authors would like to thank the associate editors and the reviewers for their useful feedback that improved this paper.

Funding

Six Talent Peaks Project in Jiangsu Province, Grant/Award Number: GDZB-040;

National Natural Science Foundation of China, Grant/Award Number: 51005124.

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Authors and Affiliations

  1. School of Mechanical and Electronic Engineering, Nanjing Forestry University, Nanjing, 210037, Jiangsu Province, China

    Y. Li, J. Li, M. Mao, H. Yin & X. Ni

  2. Jiangsu Key Laboratory for Design and Manufacture of Micro/Nano Biomedical Instruments Micro-Tech (Nanjing) Co., Ltd., Nanjing, 210032, Jiangsu Province, China

    C. Pan

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  1. Y. Li
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Correspondence to X. Ni.

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Li, Y., Li, J., Mao, M. et al. Investigation on the Design and Application of Hydraulic Loading Fatigue Test Device for Non-Vascular Stent. Exp Tech (2023). https://doi.org/10.1007/s40799-023-00685-7

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