Abstract
Acute kidney injury (AKI) is a common complication in children with hematological malignancies. Although AKI due to infiltration of tumor cells in children is rare, it negatively impacts treatment outcomes and increases the risk of mortality. We introduce a case of a child with acute lymphoblastic leukemia (ALL) who experienced kidney relapse resulting in asymptomatic AKI after remission from treatment, to remind clinicians not to overlook the primary disease in clinical judgment. In cases of unexplained AKI, kidney biopsy should be performed when feasible to get an accurate diagnosis and scientific treatment. In brief, children with leukemia who have achieved remission after treatment still need regular monitoring of urine routine and kidney function.
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Construction Project of Research Division of Children’s Kidney Disease of Wuhan Children’s Hospital (2022FEYJS003).
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BC and HZ: manuscript drafting. CQ: kidney pathology analysis. GZ and LH: data collection and follow-up. XW: review and final approval. All authors contributed to the article and approved the submitted version.
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Cheng, B., Zhang, H., Qi, C. et al. Extramedullary relapsed acute lymphoblastic leukemia presenting as asymptomatic acute kidney injury after hematopoietic stem cell transplantation. Pediatr Nephrol 39, 1779–1781 (2024). https://doi.org/10.1007/s00467-023-06229-w
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DOI: https://doi.org/10.1007/s00467-023-06229-w