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The impact of physical disability on the risk of gastric cancer incidence in elderly patients with diabetes: a focus on regional disparity

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Abstract

Purpose

Elderly patients with type 2 diabetes mellitus (T2DM) may have a higher risk of physical disability. This study investigated the incidence of gastric cancer according to physical disability status in elderly patients with T2DM.

Methods

The National Health Insurance Service claims data were used. A total of 76,162 participants aged 60 years or above, diagnosed with T2DM, were included. The association between physical disability status and gastric cancer incidence was evaluated using the Cox regression analysis. Additionally, subgroup analysis was performed according to region.

Results

A total of 9,154 (12.0%) individuals had physical disability. Gastric cancer incidence was more common in participants with physical disability (3.3%) than those without (2.4%). A higher risk of gastric cancer incidence was found in elderly T2DM patients with physical disability (Hazard Ratio (HR) 1.18, 95% Confidence Interval (95% CI) 1.04–1.34). Such tendencies were maintained regardless of region, although the effect of physical disability status on gastric cancer incidence was particularly significant in individuals residing in non-metropolitan areas (HR: 1.19, 95% CI: 1.01–1.40).

Conclusion

Elderly patients with T2DM who had physical disability showed a higher risk of gastric cancer incidence. The findings suggest a need to monitor elderly T2DM patients with disability as they may be susceptible to difficulties in accessing cancer-related healthcare.

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Data Availability

The data that support the findings of this study are available from the National Health Insurance Service.

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Funding

This work was supported by a grant from the National Cancer Center (NCC-2210802-2) of Korea.

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Author notes

  1. Mingee Choi and Woo-Ri Lee contributed equally to this study.

Authors and Affiliations

  1. Department of Healthcare Management, Graduate School of Public Health, Yonsei University, Seoul, Republic of Korea

    Mingee Choi

  2. Department of Research and Analysis, National Health Insurance Service Ilsan Hospital, Goyang-si, Gyeonggi-do, Republic of Korea

    Woo-Ri Lee

  3. Division of Cancer Control & Policy, National Cancer Control Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea

    Kyu-Tae Han & Woorim Kim

  4. National Hospice Center, National Cancer Control Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea

    Woorim Kim

Authors
  1. Mingee Choi
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Contributions

Conceptualization: Mingee Choi, Woo-Ri Lee, Kyu-Tae Han, Woorim Kim; Methodology: Mingee Choi, Woo-Ri Lee, Woorim Kim; Data curation: Woo-Ri Lee; Formal analysis: Woo-Ri Lee; Writing- original draft: Woorim Kim; Writing- review & editing: Mingee Choi, Woorim Kim.

Corresponding author

Correspondence to Woorim Kim.

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Ethical statement

This study used secondary data in which all personal information were anonymized and de-identified. Ethical approval was waived by the Institutional Review Board of the National Cancer Center of Korea (NCC2023-0041).

Consent to participate

This study only used secondary data in which all personal information was anonymized and encrypted.

Competing interests

The authors declare no competing interests.

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Choi, M., Lee, WR., Han, KT. et al. The impact of physical disability on the risk of gastric cancer incidence in elderly patients with diabetes: a focus on regional disparity. Cancer Causes Control 35, 705–710 (2024). https://doi.org/10.1007/s10552-023-01840-6

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  • DOI: https://doi.org/10.1007/s10552-023-01840-6

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