Abstract
This study investigated the genotoxic risk of chronic exposure of hemolymph’s cells of Drosophila melanogaster (Insecta, Diptera) to water samples from Boqueirão de Parelhas Dam and from Lucrécia Dam in the semiarid region of Brazil. The dams are located over the Pegmatite Province of Borborema, with rocks rich in uranium and thorium. Water samples hydrated a culture medium composed of mashed potatoes, where larvae of D. melanogaster fed for 24 h, before be underwent to the Comet assay. The same water was evaluated for the presence of dissolved Radon gas (222Rn) and concentrations of 11 toxic metals (Ag, Al, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb and Zn). The results indicated a genotoxic effect resulting from exposure to the waters of the Parelhas dam, in the samples of August 2018; and in Lucrécia dam, in January 2019. D. melanogaster stood out for its high sensitivity to monitor the genotoxic effects of compounds dissolved in public dams. And unlike to other essentially aquatic sentinel organisms, this species stood out as a model to concomitant studies of air and water possible contaminated, in a scenario of natural environmental radioactivity present in semiarid of Brazil.
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Funding
The work was funded by the Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco (FACEPE, APQ1431.201/19), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) - Financing Code 001, Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), and the Pró-Reitoria de Pesquisa e Pós-Graduação, Universidade Federal de Pernambuco (UFPE).
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do Nascimento-Silva, C., do Carmo-Neto, E.F., de Santana, S.L. et al. Accessing the Health Risk of Ingestion of Surface Water from Lucrécia and Parelhas Dams in Northeast Brazil Using the Sentinel Organism Drosophila melanogaster. Bull Environ Contam Toxicol 112, 12 (2024). https://doi.org/10.1007/s00128-023-03838-x
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DOI: https://doi.org/10.1007/s00128-023-03838-x