Issue 3, 2024

Chemistry and biology of specialized metabolites produced by Actinomadura

Abstract

Covering: up to the end of 2022

In recent years rare Actinobacteria have become increasingly recognised as a rich source of novel bioactive metabolites. Actinomadura are Gram-positive bacteria that occupy a wide range of ecological niches. This review highlights about 230 secondary metabolites produced by Actinomadura spp., reported until the end of 2022, including their bioactivities and selected biosynthetic pathways. Notably, the bioactive compounds produced by Actinomadura spp. demonstrate a wide range of activities, including antimicrobial, antitumor and anticoccidial effects, highlighting their potential in various fields.

Graphical abstract: Chemistry and biology of specialized metabolites produced by Actinomadura

Article information

Article type
Review Article
Submitted
09 Oct 2023
First published
15 Dec 2023
This article is Open Access
Creative Commons BY license

Nat. Prod. Rep., 2024,41, 370-401

Chemistry and biology of specialized metabolites produced by Actinomadura

Y. Dashti and J. Errington, Nat. Prod. Rep., 2024, 41, 370 DOI: 10.1039/D3NP00047H

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