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J Neurol Surg B Skull Base
DOI: 10.1055/a-2219-2551
Original Article

Outcomes of Extended Middle Fossa Approach for Petroclival Tumors in the Elderly

Vivian F. Kaul
1   Department of Otolaryngology Head and Neck Surgery, The Ohio State University, Columbus, Ohio, United States
2   Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center, Houston, Texas, United States
,
Micah K. Harris
3   College of Medicine, The Ohio State University, Columbus, Ohio, United States
,
Masanari Kato
1   Department of Otolaryngology Head and Neck Surgery, The Ohio State University, Columbus, Ohio, United States
,
Guilherme Finger
3   College of Medicine, The Ohio State University, Columbus, Ohio, United States
,
Thomas Gao
2   Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center, Houston, Texas, United States
,
Douglas A. Hardesty
3   College of Medicine, The Ohio State University, Columbus, Ohio, United States
,
Daniel M. Prevedello
3   College of Medicine, The Ohio State University, Columbus, Ohio, United States
,
Yin Ren
2   Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center, Houston, Texas, United States
,
Oliver F. Adunka
2   Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center, Houston, Texas, United States
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Abstract

Objective The aims of the study are (1) to evaluate the extended middle fossa approach (eMCF) for resection of tumors in the petroclivus and anterior cerebellopontine angle (CPA) and (2) to compare surgical outcomes between elderly (≥65 years) and nonelderly patients.

Design Retrospective cohort.

Setting Tertiary referral center.

Participants Adults with petroclival, anterior CPA, or posterior fossa lesions who underwent an eMCF approach from 2012 to 2021 were included in the study.

Main Outcome Measure Demographics, symptoms, cranial nerve (CN) function, and postoperative outcomes.

Results Twenty-nine patients (mean age of 55 years, 59% females) were identified. Eleven (38%) were ≥65 years (65–79 years). The most common pathology was meningioma (n = 13, 45%), followed by vestibular schwannoma (n = 4, 14%) and squamous cell carcinoma (n = 3, 10%). Nineteen tumors (65.5%) were located in the petroclivus, 7 (24%) involved the cavernous sinus, and 10 (34%) were located in the posterior fossa. The mean tumor maximal diameter was 3.4 cm (range: 1.3–7.9 cm). Gross total tumor resection was accomplished in 15 (52%) patients. Most patients (n = 23, 79%) did not develop new CN deficits postoperatively. Of the 13 patients who had complete pre- and postoperative audiometric data, 69% (n = 9) maintained their hearing. Comparing the elderly versus nonelderly patients, there were no significant differences in the development of new CN palsies (p = 0.14), length of stay (p = 0.91), or incidence of postoperative complications (p = 0.30).

Conclusions The eMCF approach provides exposure to the petroclival region, anterior CPA cistern, and posterior fossa for a variety of pathologies. It has a favorable safety profile in the elderly (≥65 years) population with low morbidity.

Keywords

extended middle fossa - Kawase - petroclival - vestibular schwannoma - meningioma - elderly

Previous Presentations

The abstract was presented at the North American Skull Base Association Annual Meeting, Phoenix, AZ, 2022.




Publication History

Received: 12 July 2023

Accepted: 25 November 2023

Accepted Manuscript online:
29 November 2023

Article published online:
22 December 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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