1887

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Volume 73, Issue 1

Genomic characterization of isolated from a dog bite induced cat wound reveals multiple horizontal gene transfer events and loss of the CRISPR/Cas system Open Access

Abstract

A domestic short hair cat () suffering from a purulent wound infection resulting from a dog bite was sampled for bacterial culture and isolation as the wound had been unresponsive to prolonged antimicrobial treatment. A mycoplasma was isolated from the wound. Whole genome sequencing of the isolate was performed using short-read Illumina and long-read Oxford Nanopore chemistry, and the organism was identified as . Comparison of the genome sequence of the isolate to a reference genome sequence (canid isolate) identified the loss of several key bacterial factors involved in genome editing, as well the insertion of several novel ORFs most closely related to those found in other canine mycoplasmas, specifically and . This is only the second known report of disease caused by in a non-canid species, and the first report of it infecting and causing clinical disease in a cat.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): cat , dog bite , genome sequence , mycoplasma , Mycoplasma edwardii and wound infection
© 2024 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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2024-01-03
2024-04-28
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Genomic characterization of Mycoplasma edwardii isolated from a dog bite induced cat wound reveals multiple horizontal gene transfer events and loss of the CRISPR/Cas system
J. Med. Microbiol. 73, 001788 (2024); https://doi.org/10.1099/jmm.0.001788
/content/journal/jmm/10.1099/jmm.0.001788
/content/journal/jmm/10.1099/jmm.0.001788
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