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Monitoring of optic sheath diameter during acute migraine attack: an objective criteria for the severity of disease

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Abstract

Background

The etiology of migraine can be complex and multifactorial but not clear, also, intracranial pressure has been already associated with migraine attacks. This study aimed to monitor intracranial pressure during migraine attack to understand the possible relations with disease and severity.

Methods

A prospective randomized study was designed. Patients with a definitive diagnosis of migraine underwent ultrasonography for optic nerve sheath diameter (ONSD) measurement before treatment and were re-measured after the attack was resolved. The severity of the migraine was assessed with Headache Impact Test-6 (HIT-6) and Migraine Disability Assessment (MIDAS) questionnaire before the treatment and after the symptoms regressed. ONSD values and scores from the questionnaires were compared before and after the migraine attack.

Results

The study included 11 (52.4%) women and 10 (47.6%) men, and 42 eyes were evaluated. ONSD was detected as 4.23 ± 0.26 mm in the right eye and 4.10 ± 0.32 mm in the left eye during the migraine attack and decreased to 3.65 ± 0.41 mm in the right eye and 3.50 ± 0.33 mm in the left eye after the attack was treated (p < 0.001, both). A similar statistical improvement was found in HIT-6 and MIDAS scores with ONSD after treatment (p < 0.001). A significant positive correlation was found between the ONSD value in both eyes and HIT-6/MIDAS scores during the migraine attack, and also, after the migraine attack.

Conclusion

A subjective increase of ONSD values during the migraine attack decreased after the disease resolved, also changes in ONSD values were significantly correlated with the severity of symptoms.

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Data availability

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Funding

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Radiology Department, Nusaybin State Hospital, Mardin, Turkey

    Sadullah Şimşek

  2. Neurology Department, Nusaybin State Hospital, Mardin, Turkey

    Edip Gültekin

  3. Otolaryngology-Head and Neck Surgery Clinic, Acıbadem Eskişehir Hospital, Eskisehir, Turkey

    Akif İşlek

Authors
  1. Sadullah Şimşek
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  2. Edip Gültekin
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  3. Akif İşlek
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Correspondence to Sadullah Şimşek.

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Şimşek, S., Gültekin, E. & İşlek, A. Monitoring of optic sheath diameter during acute migraine attack: an objective criteria for the severity of disease. Acta Neurol Belg (2024). https://doi.org/10.1007/s13760-023-02454-0

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