Skip to main content

Advertisement

SpringerLink
Log in

Pseudocereal Oils, Authenticated by Fourier Transform Infrared Spectroscopy, and their Chemopreventive Properties

  • Research
  • Published:
Plant Foods for Human Nutrition Aims and scope Submit manuscript

Abstract

Amaranth, quinoa, and buckwheat are the representatives of pseudocereals, different parts and by-products of which are used in daily nutrition and food processing industry. However, only scarce information exists on the bioactivity of their oils. Thus, oils obtained from amaranth, buckwheat, and red, yellow, and white quinoa seeds were evaluated in terms of their nutritional (fatty acid profile, squalene), cytotoxic (against normal and neoplastic gastrointestinal, prostate, and skin cells), anti-inflammatory and antiradical (interleukin 6, TNF-alpha, nitric oxide, DPPH, Total phenolics, and superoxide dismutase) potential in the in vitro model. Linoleic (42.9–52.5%) and oleic (22.5–31.1%) acids were the two main unsaturated, while palmitic acid (4.9–18.6%) was the major saturated fatty acid in all evaluated oils. Squalene was identified in all evaluated oils with the highest content in amaranth oil (7.6 g/100 g), and the lowest in buckwheat oil (2.1 g/100 g). The evaluated oils exerted a high direct cytotoxic impact on cancer cells of different origins, but also revealed anti-inflammatory and antiradical potentials. Yellow quinoa oil was the most active, especially toward skin (A375; IC50 6.3 µg/mL), gastrointestinal (HT29 IC50 4.9 µg/mL), and prostate cancer cells (LNCaP IC50 7.6 µg/mL). The observed differences in the activity between the oils from the tested quinoa varieties deserve further studies. High selectivity of the oils was noted, which indicates their safety to normal cells. The obtained results indicate that the oils are good candidates for functional foods with perspective chemopreventive potential.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Data Availability

No datasets were generated or analysed during the current study.

References

  1. Jan N, Hussain SZ, Naseer B et al (2023) Amaranth and Quinoa as potential nutraceuticals: a review of anti-nutritional factors, health benefits and their applications in food, medicinal and cosmetic sectors. Food Chem X 18:100687. https://doi.org/10.1016/j.fochx.2023.100687

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Martínez-Villaluenga C, Peñas E, Hernández-Ledesma B (2020) Pseudocereal grains: nutritional value, health benefits and current applications for the development of gluten-free foods. Food Chem Toxicol 137:111178. https://doi.org/10.1016/j.fct.2020.111178

    Article  CAS  PubMed  Google Scholar 

  3. Ryan E, Galvin K, O’Connor TP et al (2007) Phytosterol, squalene, tocopherol content and fatty acid profile of selected seeds, grains, and legumes. Plant Foods Hum Nutr 62: 85–91. https://doi.10.1007/s11130-007-0046-8

  4. Aghajanpour M, Nazer MR, Obeidavi Z et al (2017) Functional foods and their role in cancer prevention and health promotion: a comprehensive review. Am J Cancer Res 7(4):740–769

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Paśko P, Tyszka-Czochara M, Namieśnik J et al (2019) Cytotoxic, antioxidant and binding properties of polyphenols from the selected gluten-free pseudocereals and their by-products: in vitro model. J Cereal Sci 87:325–333. https://doi.org/10.1016/j.jcs.2019.04.009

    Article  CAS  Google Scholar 

  6. Taniya MS, Reshma MV, Shanimol PS et al (2020) Bioactive peptides from amaranth seed protein hydrolysates induced apoptosis and antimigratory effects in breast cancer cells. Food Biosci 35:100588. https://doi.org/10.1016/j.fbio.2020.100588

    Article  CAS  Google Scholar 

  7. Pasko P, Gdula-Argasinska J, Podporska-Carroll J et al (2015) Influence of selenium supplementation on fatty acids profile and biological activity of four edible amaranth sprouts as new kind of functional food. J Food Sci Technol 52:4724–4736. https://doi.org/10.1007/s13197-014-1602

    Article  CAS  PubMed  Google Scholar 

  8. Benito-Román O, Rodríguez-Perrino M, Sanz MT et al (2018) Supercritical carbon dioxide extraction of quinoa oil: study of the influence of process parameters on the extraction yield and oil quality. J Supercrit Fluids 139:62–71. https://doi.org/10.1016/j.supflu.2018.05.009

    Article  CAS  Google Scholar 

  9. Wróbel-Biedrawa D, Grabowska K, Galanty A et al (2020) Anti-melanoma potential of two benzoquinone homologues embelin and rapanone-a comparative in vitro study. Toxicol in Vitro 65:104826. https://doi.org/10.1016/j.tiv.2020.104826

    Article  CAS  PubMed  Google Scholar 

  10. Paśko P, Zagrodzki P, Okoń K et al (2022) Broccoli sprouts and their influence on thyroid function in different in vitro and in vivo models. Plants 11(20):2750. https://doi.org/10.3390/plants11202750

    Article  CAS  PubMed  Google Scholar 

  11. Paśko P, Prochownik E, Krośniak M et al (2020) Animals in iodine deficiency or sulfadimethoxine models of thyroid damage are differently affected by the consumption of Brassica sprouts. Biol Trace Elem Res 193:204–213. https://doi.org/10.1007/s12011-019-01694-7

    Article  CAS  PubMed  Google Scholar 

  12. Wijngaard HH, Arendt EK (2006) Buckwheat Cereal Chem 83:391–401. https://doi.org/10.1094/CC-83-0391

    Article  CAS  Google Scholar 

  13. Bonafaccia G, Marocchini M, Kreft I (2003) Composition and technological properties of the flour and bran from common and tartary buckwheat. Food Chem 80:9–15. https://doi.org/10.1016/S0308-8146(02)00228-5

    Article  CAS  Google Scholar 

  14. Jahaniaval F, Kakuda Y, Marcone MF (2000) Fatty acid and triacylglycerol compositions of seed oils of five Amaranthus accessions and their comparison to other oils. J Am Oil Chem Soc 77:847–852. https://doi.org/10.1007/s11746-000-0135-0

    Article  CAS  Google Scholar 

  15. Shen Y, Zheng L, Peng Y et al (2022) Physicochemical, antioxidant and anticancer characteristics of seed oil from three Chenopodium quinoa genotypes. Molecules 27:2453. https://doi.org/10.3390/molecules27082453

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Gamel TH, Mesallam AS, Damir AA et al (2007) Characterization of amaranth seed oils. J Food Lipids 14:323–334. https://doi.org/10.1111/j.1745-4522.2007.00089.x

    Article  CAS  Google Scholar 

  17. León-Camacho M, García-González DL, Aparicio R (2001) A detailed and comprehensive study of amaranth (Amaranthus cruentus L.) oil fatty profile. Eur Food Res Technol 213:349–355. https://doi.org/10.1007/s002170100340

    Article  Google Scholar 

  18. Deng DH, Xu L, Ye ZH et al (2012) FTIR spectroscopy and chemometric class modeling techniques for authentication of Chinese sesame oil. J Amer Oil Chem Soc 89:1003–1009. https://doi.org/10.1007/s11746-011-2004-8

    Article  ADS  CAS  Google Scholar 

  19. Poiana MA, Alexa E, Munteanu MF et al (2015) Use of ATR-FTIR spectroscopy to detect the changes in extra virgin olive oil by adulteration with soybean oil and high temperature heat treatment. Open Chem 13:689–698. https://doi.org/10.1515/chem-2015-0110

    Article  CAS  Google Scholar 

  20. Grundy MM, Momanyi DK, Holland C et al (2020) Effects of grain source and processing methods on the nutritional profile and digestibility of grain amaranth. J Funct Foods 72:104065. https://doi.org/10.1016/j.jff.2020.104065

    Article  CAS  Google Scholar 

  21. Tarhan İ (2021) A new and rapid analysis method for the most important herbal squalene source: comparison of UV–visible, fluorescence, and FTIR techniques for the quantification of squalene in amaranth seed oil. Microchem J 168:106446. https://doi.org/10.1016/j.microc.2021.106446

    Article  CAS  Google Scholar 

  22. Ortega J, Martínez Zavala A, Hernández M et al (2012) Analysis of trans fatty acids production and squalene variation during amaranth oil extraction. Cent Eur J Chem 10:1773–1778. https://doi.org/10.2478/s11532-012-0104-4

    Article  CAS  Google Scholar 

  23. Grever M, Schepartz S, Chabner B (1992) The National Cancer Institute: Cancer drug discovery and development program. Semin Oncol 19:622–638

    CAS  PubMed  Google Scholar 

  24. Wolosik K, Chalecka M, Palka J et al (2023) Protective effect of Amaranthus cruentus seed oil on the UVA radiation-induced apoptosis in human skin fibroblasts. Int J Mol Sci 24:10795. https://doi.org/10.20944/preprints202305.1369.v1

    Article  Google Scholar 

  25. Lacatusu I, Arsenie LV, Badea G et al (2018) New cosmetic formulations with broad photoprotective and antioxidative activities designed by amaranth and pumpkin seed oils nanocarriers. Ind Crops Prod 123:424–433. https://doi.org/10.1016/j.indcrop.2018.06.083

    Article  CAS  Google Scholar 

  26. Gandhi P, Samarth RM, Peter K (2020) Bioactive compounds of amaranth (Genus Amaranthus). In: Bioactive compounds in underutilized vegetables and legumes. Springer, Cham, p 1–37. https://doi.org/10.1007/978-3-030-57415-4_3

  27. Lin HC, Lin JY (2016) Immune cell–conditioned media suppress prostate cancer PC-3 cell growth correlating with decreased proinflammatory/anti-inflammatory cytokine ratios in the media using 5 selected crude polysaccharides. Integr Cancer Ther 15:13–25. https://doi.org/10.1177/1534735415627923

    Article  CAS  Google Scholar 

  28. Galanty A, Zagrodzki P, Gdula-Argasińska et al (2021) A comparative survey of anti-melanoma and anti-inflammatory potential of usnic acid enantiomers—a comprehensive in vitro approach. Pharmaceuticals 14:945. https://doi.org/10.3390/ph14090945

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Liberal Â, Calhelha RC, Pereira C et al (2016) A comparison of the bioactivity and phytochemical profile of three different cultivars of globe amaranth: red, white, and pink. Food Funct 7:679–688. https://doi.org/10.1039/c5fo01342a

    Article  CAS  PubMed  Google Scholar 

  30. Tyszka-Czochara M, Pasko P, Zagrodzki P et al (2016) Selenium supplementation of amaranth sprouts influences betacyanin content and improves anti-inflammatory properties via NFκB in murine RAW 264.7 macrophages. Biol Trace Elem Res 169:320–330. https://doi.org/10.1007/s12011-015-0429-x

    Article  CAS  PubMed  Google Scholar 

  31. Shahbaz M, Raza N, Islam M et al (2023) The nutraceutical properties and health benefits of pseudocereals: a comprehensive treatise. Crit Rev Food Sci Nutr 63:10217–10229. https://doi.org/10.1080/10408398.2022.2071205

    Article  PubMed  Google Scholar 

  32. Tang Y, Tsao R (2017) Phytochemicals in quinoa and amaranth grains and their antioxidant, anti-inflammatory, and potential health beneficial effects: a review. Mol Nutr Food Res 61:1600767. https://doi.org/10.1002/mnfr.201600767

    Article  CAS  Google Scholar 

Download references

Funding

The research has been supported by a grant from the Priority Research Area qLIFE under the Strategic Programme Excellence Initiative at Jagiellonian University. The publication was created with the use of equipment, the purchase of which has been supported by a grant from the Priority Research Area qLIFE under the Strategic Programme Excellence Initiative at Jagiellonian University (No. 06/IDUB/2019/94).

Author information

Authors and Affiliations

  1. Department of Food Chemistry and Nutrition, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland

    Paweł Paśko & Paweł Zagrodzki

  2. Department of Pharmacognosy, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland

    Agnieszka Galanty

  3. Centro de Desarrollo de Productos Bióticos, Instituto Politécnico Nacional, Yautepec, Mexico

    Emilia Ramos-Zambrano & Alma Leticia Martinez Ayala

  4. Food Science and Technology, Department of Family and Consumer Sciences, New Mexico State University, New Mexico, USA

    Efren Delgado

  5. Center of Excellence in Sustainable Food and Agricultural Systems, New Mexico State University, New Mexico, USA

    Efren Delgado

  6. Department of Radioligands, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland

    Joanna Gdula- Argasińska

  7. Institute of Physics, Faculty of Natural Sciences, Jan Kochanowski University, Kielce, Poland

    Robert Podsiadły

  8. Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University, Jerusalem, Israel

    Joseph Deutsch & Shela Gorinstein

Authors
  1. Paweł Paśko
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Agnieszka Galanty
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Emilia Ramos-Zambrano
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Alma Leticia Martinez Ayala
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Efren Delgado
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Joanna Gdula- Argasińska
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Paweł Zagrodzki
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Robert Podsiadły
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Joseph Deutsch
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Shela Gorinstein
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Conceptualization: PP, AG, ED, SG. Data curation; PP, ERZ, ALMA, JGA, JD, SG. Formal analysis; PP, AG, ERZ, JGA, PZ, RP. Funding acquisition: PP, EG, PZ, SG. Investigation: PP, AG, ERZ, JGA. Methodology: AG, JGA, ERZ, PZ, RP, JD, SG. Project administration; PP and SG. Resources: PP, ALMA, ED, JD, SG. Software: PZ, RP, PP. Supervision; ED, PZ, ALMA, SG. Validation; ERZ, AG, JGA, JD, RP. Visualization: PP, RP, ERZ, PZ. Writing - original draft; PP, AG, PZ, SG, and Writing - review & editing ALMA, ED, PZ, SG.

Corresponding authors

Correspondence to Paweł Paśko or Shela Gorinstein.

Ethics declarations

Ethical Approval

Not applicable.

Conflict of Interest

The authors confirm that they have no conflicts of interest.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Electronic Supplementary Material

Below is the link to the electronic supplementary material.

Supplementary Material 1

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Paśko, P., Galanty, A., Ramos-Zambrano, E. et al. Pseudocereal Oils, Authenticated by Fourier Transform Infrared Spectroscopy, and their Chemopreventive Properties. Plant Foods Hum Nutr 79, 151–158 (2024). https://doi.org/10.1007/s11130-024-01139-0

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11130-024-01139-0

Keywords

Search

Navigation