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Enhanced antifungal properties of the Ag-decorated GO and rGO nanocomposites for medical applications

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Abstract

Microbial infection is a bane to living organisms, especially humans. It is difficult to treat these infections with commercial drugs. In this context, antifungal metal oxide and carbon-based nanohybrids are an alternative due to their synergistic properties. In this work, we synthesized silver-decorated graphene oxide (Ag/GO) nanocomposite using a simple co-precipitation method. In this way, spherical silver nanoparticles are uniformly distributed over the surface of the reduced GO (rGO). The synthesized samples were characterized using various physical–chemical characterization techniques. The antifungal activity of the Ag-decorated reduced graphene oxide (Ag/rGO) composites reveals the highest zone of inhibition towards Candida albicans. It has been found that nanohybrids possess antifungal properties against C. albicans, Candida krusei and Candida tropicalis. This depends on their concentration and time of use. In-vitro antifungal activity of Ag/rGO nanocomposite reveals a higher zone of inhibition against C. albicans. These nanocomposites are useful as nanofillers in biopolymer nanocomposites for antifungal materials and potential cancer therapeutic agents.

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References

  1. Morens D M and Fauci A S 2013 PLoS. Pathog. 9 7

    Article  Google Scholar 

  2. Kline K A and Lewis A L 2016 Microbiol. Spect. 4 459

    Article  Google Scholar 

  3. Arzanlou M, Chai W C and Venter H 2017 Essays Biochem. 61 49

    Article  Google Scholar 

  4. Nawar Z, Ashreen S, Hossain M M and Ahmed A 2021 Adv. Microbiol. 11 343

    Article  CAS  Google Scholar 

  5. Butler M S and Paterson D L 2019 J. Antibiot. 73 329

    Article  Google Scholar 

  6. Hutchings M, Truman A and Wilkinson B 2019 Curr. Opin. Microbiol. 51 72

    Article  CAS  Google Scholar 

  7. Amini S M and Akbari A 2019 Mater. Sci. Eng. C 03 109809

    Article  Google Scholar 

  8. Wen L, Zhang Z, Sun D W, Sivagnanam S P and Tiwari B K 2020 Crit. Rev. Food. Sci. Nutr. 60 1826

    Article  CAS  Google Scholar 

  9. Makvandi P, Jamaledin R, Jabbari M, Nikfarjam N and Borzacchiello A 2018 Dent. Mater. 34 851

    Article  CAS  Google Scholar 

  10. Magana M, Pushpanathan M, Santos A L, Leanse L, Fernandez M, Ioannidis A et al 2020 Lancet Infect. 20 216

    Article  Google Scholar 

  11. Saha M and Sarkar A 2021 J. Xenobiotics 11 197

    Article  CAS  Google Scholar 

  12. Samreen A I, Malak H A, Abulreesh H H and Glob J 2021 Antimicrob. Resist. 27 101

    Article  CAS  Google Scholar 

  13. Namivandi-Zangeneh R, Wong E H H and Boyer C 2021 ACS Infect. Dis. 7 215

    Article  CAS  Google Scholar 

  14. Wang S, Gao Y, Ji Q and Ji J 2020 Biomater. Sci. 8 6825

    Article  CAS  Google Scholar 

  15. Gold K, Slay B, Knackstedt M and Gaharwar A K 2018 Adv. Ther. 1 1700033

    Article  Google Scholar 

  16. Yan X, He B, Liu L, Qu G, Shi J, Hu L et al 2018 Metallomics 10 557

    Article  CAS  Google Scholar 

  17. Kumar P, Huo P, Zhang R and Liu B 2019 Nanomaterials 9 737

    Article  CAS  Google Scholar 

  18. Xin Q, Shah H, Nawaz A, Xie W, Akram M Z, Batool A et al 2019 Adv. Mater. 45 1804838

    Article  Google Scholar 

  19. Hu W, Peng C, Luo W, Lv M, Li X, Li D et al 2010 ACS Nano 4 4317

    Article  CAS  Google Scholar 

  20. Hu W, Peng C, Lv M, Li X, Zhang Y, Chen N et al 2011 ACS Nano 5 3693

    Article  CAS  Google Scholar 

  21. Guo Y, Yang X, Ruan K, Kong J, Dong M, Zhang J et al 2019 ACS Appl. Mater. Interfaces 11 25465

    Article  CAS  Google Scholar 

  22. Devendirapandi G, Sahay M I, Padmanaban D, Panneerselvam A, Palraj R, Thanikasalam R et al 2023 Inorg. Chem. Com. 151 110636

    Article  Google Scholar 

  23. Dhayalan M, Immanuel M, Ayyar M, Gandhi N N, Krishnan K and Abdulhadi B 2018 J. Photochem. Photobiol. B 183 251

    Article  CAS  Google Scholar 

  24. Jin H, Guo H, Gao X and Gui R 2018 Sens. Actuators B Chem. 277 14

    Article  CAS  Google Scholar 

  25. Raj M and Goyal R N 2019 Sens. Actuators B Chem. 284 759

    Article  CAS  Google Scholar 

  26. Zhu Z, Han Y, Chen C, Ding Z, Long J and Hou Y 2018 Chem. Cat. Chem. 10 1627

    CAS  Google Scholar 

  27. Kaur B, Pandiyan T, Satpati B and Srivastava R 2013 Colloids Surf. B Biointerfaces 111 97

    Article  CAS  Google Scholar 

  28. Lorestani F, Shahnavaz Z, Mn P, Alias Y and Manan N S A 2015 Sens. Actuators B Chem. 208 389

    Article  CAS  Google Scholar 

  29. Moozarm Nia P, Lorestani F, Meng W P and Alias Y 2015 Appl. Surf. Sci. 332 648

    Article  CAS  Google Scholar 

  30. Ahmad N, Al-Fatesh A S, Wahab R, Alam M and Fakeeha A H 2020 J. Mater. Sci. Mater. Electron 31 11927

    Article  CAS  Google Scholar 

  31. Chavez-Esquivel G, Cervantes-Cuevas H, Ybieta-Olvera L F, Castañeda Briones M T, Acosta D and Cabello J 2021 Mater. Sci. Eng. C 123 111934

    Article  CAS  Google Scholar 

  32. Magaldi S, Mata-Essayag S, de Capriles C H, Perez C, Colella M T, Olaizola C et al 2004 Int. J. Infect. 8 39

    Article  CAS  Google Scholar 

  33. Shinde C H, Anand P K, Kunchiraman B N and Jadhav A B 2018 Int. J. Health Sci. Res. 8 57

    Google Scholar 

  34. Ghanim R R, Mohammad M R and Abdul Hussien A M 2018 Biosci. Biotechnol. Res. Asia 15 627

    Article  Google Scholar 

  35. Thakur A, Kumar S, Sharma M and Rangra V S 2016 Adv. Mater. Lett. 7 1029

    Article  CAS  Google Scholar 

  36. Dai C, Yang X and Xie H 2011 Mater. Res. Bull. 46 2004

    Article  CAS  Google Scholar 

  37. Yasin G, Arif M, Shakeel M, Dun Y, Zuo Y, Khan W Q et al 2018 Adv. Eng. Mater. 20 7

    Article  Google Scholar 

  38. Nabih S and Hassn S S 2020 J. Mater. Sci. Mater. Electron 31 13352

    Article  CAS  Google Scholar 

  39. Aldosari M, Alsaud K B B, Othman A, Al-Hindawi M, Faisal N H, Ahmed R et al 2020 Polymers 12 05

    Article  Google Scholar 

  40. Menazea A A and Ahmed M K 2020 J. Mol. Struct. 1218 128536

    Article  CAS  Google Scholar 

  41. Subha M, Anitha K and Jauhar R O M U 2019 J. Mol. Struct. 1179 469

    Article  CAS  Google Scholar 

  42. Kumar A, Aathira M S and Jain S 2019 New J. Chem. 49 9116

    Article  Google Scholar 

  43. Balu R and Dakshanamoorthy A 2022 J. Mater. Sci. Mater. Electron 33 10057

    Article  CAS  Google Scholar 

  44. Balu R and Dakshanamoorthy A 2022 Inorg. Chem. Com. 136 109148

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Physics, B.S. Abdur Rahman Crescent Institute of Science of Technology, Chennai, 602148, India

    M Sheeba Gnana Selvi & G V Vijayaraghavan

  2. Department of Physics, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai, 602105, India

    RO MU Jauhar

  3. Institute of Nano Science and Technology, Mohali, 140306, India

    D Sivaraj

  4. Department of Physics, Anna Adarsh College for Women, Chennai, 600040, India

    A Suvitha

  5. PG and Research Department of Physics, Pachaiyappa’s College, Chennai, 600030, India

    V Malarvizhi

Authors
  1. M Sheeba Gnana Selvi
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  2. RO MU Jauhar
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  3. D Sivaraj
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  4. A Suvitha
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  5. V Malarvizhi
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  6. G V Vijayaraghavan
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Correspondence to RO MU Jauhar.

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Selvi, M.S.G., Jauhar, R.M., Sivaraj, D. et al. Enhanced antifungal properties of the Ag-decorated GO and rGO nanocomposites for medical applications. Bull Mater Sci 47, 27 (2024). https://doi.org/10.1007/s12034-023-03106-y

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  • DOI: https://doi.org/10.1007/s12034-023-03106-y

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