Skip to main content

Advertisement

Log in

Overview of gender-affirming surgery

  • Mini symposium: Imaging of intersex and gender diverse youth
  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

This publication will discuss the diversity of procedures that are common to those with intersex traits,/differences of sex development (I/DSD), and transgender and gender diverse (TGD) patients. It will address how these procedures are performed, and common after care and long-term considerations which are relevant to the pediatric radiologist. Some surgeries offered to these patient populations have shared surgical approaches and radiographic considerations. With the growth of TGD procedures as a field, more pediatric subspecialties are performing these procedures, and the approaches are informing the surgical care of the growing number of I/DSD individuals who are seeking surgery in adolescence and young adulthood. Surgeries discussed will include procedures to masculinize or feminize breast/chest tissue, facial bony contours, as well as internal and external genital structures. Patients are diverse and this includes their embodiment goals. As such, not all TGD and I/DSD patients will desire to undergo these procedures. It is important for radiologists to have a foundational understanding of this heterogenous set of procedures so they can provide optimal care for these patient populations.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Coleman E, Radix AE, Bouman WP et al (2022) Standards of Care for the Health of Transgender and Gender Diverse People, Version 8. International Journal of Transgender Health 23:S1–S259. https://doi.org/10.1080/26895269.2022.2100644

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Lee PA, Nordenström A, Houk CP et al (2016) Global Disorders of Sex Development Update since 2006: Perceptions, Approach and Care. Horm Res Paediatr 85:158–180. https://doi.org/10.1159/000442975

    Article  CAS  PubMed  Google Scholar 

  3. Grimstad F, Kremen J, Streed CG, Dalke KB (2021) The Health Care of Adults with Differences in Sex Development or Intersex Traits Is Changing: Time to Prepare Clinicians and Health Systems. LGBT Health 8:439–443

    Article  PubMed  Google Scholar 

  4. Grimstad F, Boskey ER, Taghinia A, Ganor O (2021) Gender-affirming surgeries in transgender and gender diverse adolescent and young adults: a pediatric and adolescent gynecology primer. J Pediatr Adolesc Gynecol 34:442–448

    Article  PubMed  Google Scholar 

  5. Grimstad F, Kremen J, Boskey ER, Wenger H (2023) How Should Clinicians Navigate Decision Making About Genital Reconstructive Surgeries Among Intersex and Transgender Populations? AMA J Ethics 25:437–445. https://doi.org/10.1001/amajethics.2023.437

    Article  Google Scholar 

  6. Emans SJ, Laufer MR (2011) Emans, Laufer, Goldstein’s Pediatric and Adolescent Gynecology, 6th ed. Lippincott Williams & Wilkins, p 608

  7. James SE, Herman JL, Keisling M et al (2016) The report of the 2015 US Transgender Survey. National Center for Transgender Equality, Washington, D.C.

    Google Scholar 

  8. Callen AL, Badiee RK, Phelps A et al (2021) Facial Feminization Surgery: Key CT Findings for Preoperative Planning and Postoperative Evaluation. Am J Roentgenol 217:709–717. https://doi.org/10.2214/AJR.20.25228

    Article  Google Scholar 

  9. Tang A, Hojilla JC, Jackson JE et al (2022) Gender-Affirming Mastectomy Trends and Surgical Outcomes in Adolescents. Ann Plast Surg 88:S325–S331

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Elias N, Rysin R, Kwartin S, Wolf Y (2022) Breaking the Binary: The Approach to Chest Masculinizing Gender-Affirming Surgery in Trangender Men. Isr Med Assoc J 24:20–24

    PubMed  Google Scholar 

  11. Expert Panel on Breast Imaging, Brown A, Lourenco AP et al (2021) ACR Appropriateness Criteria® Transgender Breast Cancer Screening. J Am Coll Radiol 18:S502–S515. https://doi.org/10.1016/j.jacr.2021.09.005

    Article  Google Scholar 

  12. Grimstad F, Boskey ER, Taghinia A et al (2021) The role of androgens in clitorophallus development and possible applications to transgender patients. Andrology 9:1719–1728. https://doi.org/10.1111/andr.13016

    Article  CAS  PubMed  Google Scholar 

  13. Jun J, Song SH, Park S et al (2021) Surgical Outcomes of Clitoroplasty in Children with Congenital Adrenal Hyperplasia and Clitoral Hypertrophy: A 19-Year Experience of a Single Surgeon. Int J Environ Res Public Health 18:11152. https://doi.org/10.3390/ijerph182111152

    Article  PubMed  PubMed Central  Google Scholar 

  14. Grimstad F, McLaren H, Gray M (2021) The gynecologic examination of the transfeminine person after penile inversion vaginoplasty. Am J Obstet Gynecol 224:266–273. https://doi.org/10.1016/j.ajog.2020.10.002

    Article  PubMed  Google Scholar 

  15. Wolffenbuttel KP, Menon VS, Grimsby GM et al (2017) Clitoral hoodplasty in females with disorders of sex development. J Pediatr Urol 13:61.e1-61.e5. https://doi.org/10.1016/j.jpurol.2016.07.004

    Article  CAS  PubMed  Google Scholar 

  16. Fernandez N, Chavarriaga J, Pérez J (2021) Complete corporeal preservation clitoroplasty: new insights into feminizing genitoplasty. Int Braz J Urol 47(4):861–867. https://doi.org/10.1590/S1677-5538.IBJU.2020.0839

    Article  PubMed  PubMed Central  Google Scholar 

  17. Lee PA, Houk CP, Ahmed SF, Hughes IA (2006) Consensus Statement on Management of Intersex Disorders. Pediatrics 118:e488–e500. https://doi.org/10.1542/peds.2006-0738

    Article  PubMed  Google Scholar 

  18. Roberts CP, Haber MJ, Rock JA (2001) Vaginal creation for müllerian agenesis. Am J Obstet Gynecol 185:1349–1352. https://doi.org/10.1067/mob.2001.119075

    Article  CAS  PubMed  Google Scholar 

  19. Rink RC, Cain MP (2008) Urogenital mobilization for urogenital sinus repair. BJU Int 102:1182–1197. https://doi.org/10.1111/j.1464-410X.2008.08091.x

    Article  PubMed  Google Scholar 

  20. Breech LL, Laufer MR (1999) Obstructive anomalies of the female reproductive tract. J Reprod Med 44:233–240

    CAS  PubMed  Google Scholar 

  21. Chan JL, Levin PJ, Ford BP et al (2017) Vaginoplasty with autologous buccal mucosa fenestrated graft in two patients with vaginal agenesis: A Multidisciplinary approach and literature review. J Minim Invasive Gynecol 24:670–676. https://doi.org/10.1016/j.jmig.2016.12.030

    Article  PubMed  PubMed Central  Google Scholar 

  22. Miller RJ, Breech LL (2008) Surgical correction of vaginal anomalies. Clin Obstet Gynecol 51:223–236. https://doi.org/10.1097/GRF.0b013e31816d2181

    Article  PubMed  Google Scholar 

  23. Trotsenburg M van, Luikenaar RAC, Meriggiola MC (2023) Context, Principles and Practice of TransGynecology: Managing Transgender Patients in ObGyn Practice, New edition. Cambridge University Press, Cambridge, United Kingdom; New York, NY

  24. Pradhan S, Vilanova-Sanchez A, McCracken KA et al (2018) The Mullerian Black Box: Predicting and defining Mullerian anatomy in patients with cloacal abnormalities and the need for longitudinal assessment. J Pediatr Surg 53:2164–2169. https://doi.org/10.1016/j.jpedsurg.2018.05.009

    Article  PubMed  Google Scholar 

  25. Ferrando CA (2018) Vaginoplasty Complications. Clin Plast Surg 45:361–368

    Article  PubMed  Google Scholar 

  26. Stowell JT, Grimstad FW, Kirkpatrick DL et al (2019) Imaging Findings in Transgender Patients after Gender-affirming Surgery. Radiographics 39:1368–1392. https://doi.org/10.1148/rg.2019190010

    Article  PubMed  Google Scholar 

  27. van der Sluis WB, de Haseth KB, Elfering L et al (2020) Neovaginal discharge in transgender women after vaginoplasty: A diagnostic and treatment algorithm. International Journal of Transgender Health 21:367. https://doi.org/10.1080/26895269.2020.1725710

    Article  PubMed  PubMed Central  Google Scholar 

  28. Saltzman AF, Carrasco A, Colvin A et al (2018) Patients with disorders of sex development and proximal hypospadias are at high risk for reoperation. World J Urol 36:2051–2058. https://doi.org/10.1007/s00345-018-2350-3

    Article  PubMed  Google Scholar 

  29. Massie JP, Morrison SD, Wilson SC et al (2017) Phalloplasty with Urethral Lengthening: Addition of a Vascularized Bulbospongiosus Flap from Vaginectomy Reduces Postoperative Urethral Complications. Plast Reconstr Surg 140:551e–558e. https://doi.org/10.1097/PRS.0000000000003697

    Article  CAS  PubMed  Google Scholar 

  30. Jolly D, Wu CA, Boskey ER et al (2021) Is Clitoral Release Another Term for Metoidioplasty? A Systematic Review and Meta-Analysis of Metoidioplasty Surgical Technique and Outcomes. Sex Med 9:100294. https://doi.org/10.1016/j.esxm.2020.100294

    Article  PubMed  PubMed Central  Google Scholar 

  31. Purohit RS, Kent M, Djordjevic ML (2022) Penile Prosthesis in Transgender Men after Phalloplasty. Indian J Plast Surg 55:168–173. https://doi.org/10.1055/s-0041-1740523

    Article  PubMed  PubMed Central  Google Scholar 

  32. Frey JD, Poudrier G, Chiodo MV, Hazen A (2016) A Systematic Review of Metoidioplasty and Radial Forearm Flap Phalloplasty in Female-to-male Transgender Genital Reconstruction: Is the “Ideal” Neophallus an Achievable Goal? Plast Reconstr Surg Glob Open 4(12):e1131. https://doi.org/10.1097/GOX.0000000000001131

  33. Miller TJ, Lin WC, Safa B et al (2021) Transgender Scrotoplasty and Perineal Reconstruction With Labia Majora Flaps: Technique and Outcomes From 147 Consecutive Cases. Ann Plast Surg 87:324–330. https://doi.org/10.1097/SAP.0000000000002602

    Article  CAS  PubMed  Google Scholar 

  34. Pyle LC, Nathanson KL (2017) A practical guide for evaluating gonadal germ cell tumor predisposition in differences of sex development. Am J Med Genet C Semin Med Genet 175:304–314. https://doi.org/10.1002/ajmg.c.31562

    Article  PubMed  PubMed Central  Google Scholar 

  35. ACOG Committee on Gynecologic Practice (2019) ACOG Committee Opinion No. 774: Opportunistic Salpingectomy as a Strategy for Epithelial Ovarian Cancer Prevention. Obstet Gynecol 133:e279–e284. https://doi.org/10.1097/AOG.0000000000003164

    Article  Google Scholar 

  36. Grimstad F, Boskey E (2020) Empowering transmasculine youth by enhancing reproductive health counseling in the primary care setting. J Adolesc Health 66:653–655

    Article  PubMed  Google Scholar 

  37. Grimstad FW, Fraiman E, Garborcauskas G, Ferrando CA (2023) Retrospective review of changes in testosterone dosing and physiologic parameters in transgender and gender-diverse individuals following hysterectomy with and without oophorectomy. J Sex Med 20:690–698. https://doi.org/10.1093/jsxmed/qdad031

    Article  PubMed  Google Scholar 

  38. Asokan A, Sudheendran MK (2022) Gender Affirming Body Contouring and Physical Transformation in Transgender Individuals. Indian J Plast Surg 55:179–187. https://doi.org/10.1055/s-0042-1749099

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgements

None.

Author information

Authors and Affiliations

Authors

Contributions

Frances Grimstad: Conceptualization, Writing- Original draft preparation. Jessica Lee: Conceptualization, Writing- Reviewing and Editing. All authors reviewed and approved final manuscript.

Corresponding author

Correspondence to Frances W. Grimstad.

Ethics declarations

Disclosures

The authors report no conflicts of interest or disclosures.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Grimstad, F.W., Lee, J. Overview of gender-affirming surgery. Pediatr Radiol (2024). https://doi.org/10.1007/s00247-024-05874-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00247-024-05874-z

Keywords

Navigation