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Current Pharmaceutical Biotechnology

Editor-in-Chief

ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

Mini-Review Article

Unconventional Remedies for Squamous Cell Carcinoma: A Journey into Alternative Treatments

In Press, (this is not the final "Version of Record"). Available online 12 February, 2024
Author(s): Elen Deng and Amor Khachemoune*
Published on: 12 February, 2024

DOI: 10.2174/0113892010286715240119061108

Price: $95

Abstract

Squamous cell carcinoma (SCC) is the second most common form of skin cancer and is typically found on sun-exposed skin. Risk factors include ultraviolet radiation exposure, older age, fairer complexion, smoking, and immunosuppression. SCC is a slow-growing tumor with the possibility of metastasis if not treated. The clinical presentation can range from a dry, scaly erythematous patch or plaque to a firm hyperkeratotic papule, plaque, or nodule, depending on the histological type via biopsy. The first-line therapies for SCC removal are standard excision and Mohs microscopic surgery; however, there are novel and alternative non-surgical options being considered for the treatment of SCC. This review summarizes the current guidelines for treating low-risk and high-risk SCC and discusses rare, experimental, and anecdotal non-surgical treatments for SCC in the literature.

Keywords: Squamous Cell Carcinoma, Skin Cancer, Non-melanoma Skin Cancer, alternative treatment, herbal, natural remedies


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