1887

Journal of Medical Microbiology logo

Volume 73, Issue 2

Genomic and metabolic versatility of contributes to its inter-kingdom transmission and survival Open Access

Abstract

is one of the most versatile bacteria with renowned pathogenicity and extensive drug resistance. The diverse habitats of this bacterium include fresh, saline and drainage waters, soil, moist surfaces, taps, showerheads, pipelines, medical implants, nematodes, insects, plants, animals, birds and humans. The arsenal of virulence factors produced by includes pyocyanin, rhamnolipids, siderophores, lytic enzymes, toxins and polysaccharides. All these virulent elements coupled with intrinsic, adaptive and acquired antibiotic resistance facilitate persistent colonization and lethal infections in different hosts. To date, treating pulmonary diseases remains complicated due to the chronic secondary infections triggered by hospital-acquired . On the contrary, this bacterium can improve plant growth by suppressing phytopathogens and insects. Notably, is one of the very few bacteria capable of trans-kingdom transmission and infection. Transfer of strains from plant materials to hospital wards, animals to humans, and humans to their pets occurs relatively often. Recently, we have identified that plant-associated strains could be pathologically similar to clinical isolates. In this review, we have highlighted the genomic and metabolic factors that facilitate the dominance of across different biological kingdoms and the varying roles of this bacterium in plant and human health.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): abiotic stress , biotic stress , COPD , cystic fibrosis , genomic plasticity , growth promotion , husbandry , plant health , plant pathogenicity , pulmonary diseases and virulence
© 2024 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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2024-02-16
2024-04-27
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.001791
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Genomic and metabolic versatility of Pseudomonas aeruginosa contributes to its inter-kingdom transmission and survival
J. Med. Microbiol. 73, 001791 (2024); https://doi.org/10.1099/jmm.0.001791
/content/journal/jmm/10.1099/jmm.0.001791
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