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Task-specific approach in customized design of EEG system for small laboratory animals

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Abstract

Electroencephalography (EEG) of small animal models of brain disorders is the powerful method of neurophysiology that requires efficient, low cost and flexible instrumentation. Most of the commercially available EEG systems for small animals are not flexible enough and do not allow for task-specific modifications, while custom systems developed for a specific task are typically hard to be reproduced because of its specific design.We propose a modular EEG platform with Bluetooth low energy wireless interface that features both implantable and tethered use and allows for easy task-specific adaptation. To illustrate the proposed designapproach, we present a low-cost autonomous instrument for photobiomodulation of mouse brain during deep sleep.

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Funding

E.I., D.M., D.T., S.P., I.B., A.T., V.A., D.Z. were supported by RSF № 23–75-30001.

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Authors and Affiliations

  1. Institute of Physics, Saratov State University, Astrakhanskaya Str. 83, 410012, Saratov, Russia

    Egor Ilyukov, Dmitry Myagkov, Dmitry Tuktarov, Sergey Popov & Timofey Inozemtsev

  2. Department of Biology, Saratov State University, Astrakhanskaya 82, 410012, Saratov, Russia

    Inna Blokhina, Andrey Terskov, Viktoria Adushkina & Daria Zlatogorskaya

Authors
  1. Egor Ilyukov
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  2. Dmitry Myagkov
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  3. Dmitry Tuktarov
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  4. Sergey Popov
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  5. Timofey Inozemtsev
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  6. Inna Blokhina
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  7. Andrey Terskov
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  8. Viktoria Adushkina
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  9. Daria Zlatogorskaya
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Contributions

EI initiated and supervised this article. IT and VT wrote Abstract and Conclusions; Introduction, Results and Conclusions; MZ made the statistical analysis; IB, AE, DZ, VA, AT performed most experiments. All authors were also involved in the editing of the manuscript; SP prepared the figures. All authors were also involved in the editing of the manuscript; IB prepared the figures. All authors have read and agreed to the published version of the manuscript.

Corresponding author

Correspondence to Egor Ilyukov.

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The authors declare that they have no competing interests.

Ethics approval

All experimental procedures were performed in accordance with the “Guide for the Care and Use of Laboratory Animals”, Directive 2010/63/EU on the Protection of Animals Used for Scientific Purposes, and the guidelines from the Ministry of Science and High Education of the Russian Federation (No. 742 from 13.11.1984), which have been approved by the Bioethics Commission of the Saratov State University (Protocol No. 7).

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Ilyukov, E., Myagkov, D., Tuktarov, D. et al. Task-specific approach in customized design of EEG system for small laboratory animals. Eur. Phys. J. Spec. Top. (2024). https://doi.org/10.1140/epjs/s11734-023-01082-2

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  • DOI: https://doi.org/10.1140/epjs/s11734-023-01082-2

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