Abstract
Background
The main aim of periodontal therapy is to halt the progression of periodontitis. Curcumin, one of the main components of Curcumin longa, has been well known to possess antimicrobial, anti-inflammatory, and even anticarcinogenic properties. This systematic review assessed the impact of local application of curcumin in the pocket on the clinical and microbiologic parameters as an adjunct to scaling and root planing in periodontitis patients.
Methods
The electronic literature search retrieved 61 studies from PubMed, MEDLINE, and ScienceDirect. After screening titles, abstracts, and keywords and reading through these articles, we identified 9 articles meeting all inclusion criteria, which were included for systematic review.
Results
There was a significant difference in both clinical parameters in a short duration of a month after curcumin chips were placed as an adjunct to scaling and root planing as compared to the control. Local application of curcumin also results in slight to significant reduction in the red complex microorganisms.
Conclusion
This review suggested that local application of curcumin can be considered as a viable adjunct to mechanical debridement in periodontitis. However, further studies need to be conducted to establish its optimum dose, delivery method, and frequency in achieving the best clinical outcomes.
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Financial support was given by the Joint Committee of Ethics, International Medical University. BDS I-01–2022(09).
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TVC—idea for the article, literature search, data analysis, and critically revised the work. BSY—literature search, data analysis, and drafted the work. TYY—literature search, data analysis, and drafted the work. RB—idea for the article and critically revised the work. All authors have critically reviewed and approved the final draft and are responsible for the content and similarity index of the manuscript.
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We are deeply grateful to the Joint Committee of Ethics, International Medical University for their guidance and ethical approval. BDS I-01–2022(09).
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Chaubal, T.V., Ywen, B.S., Ying Ying, T. et al. Clinical and microbiologic effect of local application of curcumin as an adjunct to scaling and root planing in periodontitis: Systematic review. Ir J Med Sci (2024). https://doi.org/10.1007/s11845-024-03635-3
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DOI: https://doi.org/10.1007/s11845-024-03635-3