Molecules containing a chiral S(VI) moiety have found extensive applications in drug design and organic synthesis, despite a lack of diverse asymmetric methods for their creation. Now, a ligand-mediated process has enabled the production of enantioenriched S(VI)–F motifs, providing a foundation for further stereospecific elaborations.
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Melvin, P.R. Asymmetric construction of sulfur(VI)–fluorine cores. Nat. Chem. 16, 304–305 (2024). https://doi.org/10.1038/s41557-024-01454-8
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DOI: https://doi.org/10.1038/s41557-024-01454-8
