Issue 8, 2024
From the journal:

Biomaterials Science

Liquid–liquid phase separation-inspired design of biomaterials

Yang Song ORCID logo a  

a State Key Laboratory of Metal Matrix Composites, School of Material Science & Engineering, Shanghai Jiao Tong University, China
E-mail: nanosurface@sjtu.edu.cn

Abstract

Liquid–liquid phase separation (LLPS) is a crucial biological process that governs biomolecular condensation, assembly, and functionality within phase-separated aqueous environments. This phenomenon serves as a source of inspiration for the creation of artificial designs in both structured and functional biomaterials, presenting novel strategies for manipulating the structures of functional protein aggregates in a wide range of biomedical applications. This mini review summarizes my past research endeavors, offering a panoramic overview of LLPS-inspired biomaterials utilized in the design of structured materials, the development of cell mimetics, and the advancement of intelligent biomaterials.

Graphical abstract: Liquid–liquid phase separation-inspired design of biomaterials

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Article information

DOI
https://doi.org/10.1039/D3BM02008H
Article type
Minireview
Submitted
08 Dec 2023
Accepted
23 Feb 2024
First published
26 Feb 2024

Biomater. Sci., 2024,12, 1943-1949

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Liquid–liquid phase separation-inspired design of biomaterials

Y. Song, Biomater. Sci., 2024, 12, 1943 DOI: 10.1039/D3BM02008H

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