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Green Synthesis of Silica Nanoparticles/Nanocomposites for Biomedical Applications: A Narraitive Review

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Abstract—

Nanomedicine showed the unique benefits in clinical outcomes in comparison with traditional and conventional drugs in the treatment of cancer. In the future, nanomedicine therapy seems to pave the way for new treatments in cancer. In this regard, silica nanoparticles are used in various fields of technology, biomedicine and biosensing techniques due to their unique properties such as stability, biocompatibility, high surface area, significant reactivity and functionalizability. Although there are various physical and chemical methods for synthesizing silica nanoparticles, its synthesis by green method has other significant features such as being environmentally friendly, cost-effective, saving time and eliminating toxic compounds and harmful by-products that increase their application in the field of biomedicine. In the method of green synthesis of silica nanoparticles, various sources such as plants, fungi, bacteria, yeast, actinomycetes, etc. are used. In this narraitive review, various biomedical applications of green synthesized silica nanoparticles are discussed along with their examples.

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ACKNOWLEDGMENTS

The authors would like to thank Mohaghegh Ardabili University for concerning this manuscript.

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This work was supported by ongoing institutional funding. No additional grants to carry out or direct this particular research were obtained.

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Authors and Affiliations

  1. Gastroenterology and Hepatology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran

    S. M. Khoshnazar

  2. Department of Biology, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran

    A. Asadi

  3. PhD Graduate in Plant Physiology, Urmia University, Urmia, Iran

    R. Holghoomi

  4. Department of Biophysics, Faculty of Advanced Technologies, University of Mohaghegh Ardabili, Namin, Iran

    A. Abdolmaleki

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A.A conception or design of the work; data collection; data analysis and interpretation; drafting the article. R.H and SM.K data collection; critical revision of the article. A.A data collection; data analysis and interpretation. All authors contributed to the article and approved the submitted version.

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Khoshnazar, S.M., Asadi, A., Holghoomi, R. et al. Green Synthesis of Silica Nanoparticles/Nanocomposites for Biomedical Applications: A Narraitive Review. Biochem. Moscow Suppl. Ser. B 17, 41–49 (2023). https://doi.org/10.1134/S1990750823600085

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