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Current Pharmaceutical Biotechnology

Editor-in-Chief

ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

Review Article

The Hepatoprotective Effects of Ginsenoside from Ginseng: A Review of Molecular Mechanisms and Therapeutic Potentials

In Press, (this is not the final "Version of Record"). Available online 28 February, 2024
Author(s): Seyed Reza Taha*, Andarz Fazlollahpour-Naghibi, Mahdieh Shariat Zadeh, Kimia Bagheri, Hamed Rahmani Youshanlouei, Reza Mosaddeghi-Heris, Seyyed Sina Hejazian, Amirreza Khalaji, Seyedeh Shaghayegh Alavi, Payam Fattahi and Saba Mehrtabar
Published on: 28 February, 2024

DOI: 10.2174/0113892010291326240214095327

Price: $95

Abstract

Treatment of hepatic diseases presents a significant challenge due to their diverse nature. Ginsenosides, bioactive compounds derived from the root of Panax ginseng and widely used in traditional Chinese medicine, offer multifaceted protection to various organs in the body. Their versatile effects, including antioxidant, anti-inflammatory, anti-apoptotic and more, make them a promising approach for addressing hepatic disorders. This review explores the intricate molecular mechanisms and properties of ginsenosides in the prevention and treatment of liver ailments, from mild conditions to severe damage and liver fibrosis. Given the increasing prevalence of hepatic disorders, this article sheds light on the significant pharmaceutical potential of ginsenosides in the realm of hepatic disease management.

Keywords: Ginsenoside, drug-induced liver injury, alcoholic liver disease, non-alcoholic fatty liver disease, viral hepatitis, hepatic ischemia-reperfusion injury, liver fibrosis.


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