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Assessing the utilization patterns of antiparasitic drug and farmer’s perception: implications for resistance in India's dairy farming sector

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Abstract

The present investigation was done to assess the utilization patterns of antiparasitic drugs among dairy owners and their perceptions regarding resistance development. A total of 160 dairy farmers, consisting of 80 Small Dairy Farmers (SDF) and 80 Large Dairy Farmers (LDF) were selected for the study from 8 different districts of 2 states of India (Rajasthan and Uttar Pradesh). A pre-tested structured interview schedule was used for collecting data. In the study area, the majority of the dairy farmers were middle-aged males, middle-level educated and had a moderate level of experience in dairy farming. All the farmers were observed utilizing chemical antiparasitic drugs for managing parasitic infestations in dairy animals. Regarding parasite control, SDF relied on para-veterinarians, while LDF preferred self-treatment for their dairy animals. A primary source for acquiring antiparasitic drugs was pharmacy stores with and without a prescription from qualified animal health care service providers. It was found that approximately one-third of the farmers did not refer to drug labels for dose calculation. However, dairy farmers primarily relied on visual observation of animal body weight to calculate antiparasitic drug doses. The majority of the farmers stored antiparasitic drugs in their dairy farms. Moreover, the farmers expressed an average perception towards the antiparasitic resistance development. Among the various socio-economic factors, education and training were found the strongest predictors that made the highest changes in perception. The overall findings indicate that farmers were neither well-versed in the scientific practices related to the usage of antiparasitic drugs nor familiar with resistance issues. Despite this, they were continuing to acquire and administer drugs without seeking advice from the qualified veterinarians. Consequently, indiscriminate use of antiparasitic drugs in livestock sector has the potential to contribute to the emergence of resistance. It is imperative to create awareness among farmers about the importance of rational use of drugs to mitigate the risk of resistance.

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Data availability

Primary data was collected in the present study through pre-tested interview schedule.

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For data analysis, Statistical Package for Social Sciences (SPSS) was used.

References

  • Abbas RZ, Zaman MA, Colwell DD, Gilleard J, Iqbal Z (2014) Acaricide resistance in cattle ticks and approaches to its management: the state of play. Vet Parasitol 203(1–2):6–20

    Article  CAS  PubMed  Google Scholar 

  • Ahanger RR, Godara R, Katoch R, Yadav A, Bhutyal AD, Katoch M, Singh NK, Bader MA (2015) Deltamethrin resistance in field populations of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) in Jammu and Kashmir, India. Exp Appl Acarol 67:467–475

    CAS  PubMed  Google Scholar 

  • Bandyopadhyay S, Mandal S, Datta KK, Devi P, De S, Bera AK, Bhattacharya D (2010) Economic analysis of risk of gastrointestinal parasitic infection in cattle in North Eastern States of India. Trop Anim Health Prod 2:1481–1486

    Google Scholar 

  • Basic Animal Husbandry Statistics (2020–21) Department of Animal Husbandry and Dairying (DAHD), Government of India

  • Bihaqi SJ, Allaie IM, Banday MA, Sankar M, Wani ZA, Prasad A (2020) Multiple anthelmintic resistance in gastrointestinal nematodes of Caprines on Mountain Research Centre for Sheep and Goat at Kashmir Valley, India. Parasite Epidemiol Control 29(11):163

    Google Scholar 

  • Bishnoi R, Singh P, Dubey SK, Sangeetha V (2014) Gender roles in crop and animal husbandry practices and household activities with respect to changing climate in arid ecosystem. Indian Soc Ext Educ 50(1and2):1–3

    Google Scholar 

  • Bloemhoff Y, Danaher M, Forbes A, Morgan E, Mulcahy G, Power C, Sayers R (2014) Parasite control practices on pasture-based dairy farms in the Republic of Ireland. Vet Parasitol 204(3–4):352–363

    PubMed  Google Scholar 

  • Bushra M, Shahardar RA, Allaie IM, Wani ZA (2019) Efficacy of closantel, fenbendazole and ivermectin against GI helminths of cattle in central Kashmir. J Parasit Dis 43(2):289–293

    CAS  PubMed  PubMed Central  Google Scholar 

  • Chandra S, Prasad A, Yadav N, Latchumikanthan A, Rakesh RL, Praveen K, Khobra V, Subramani KV, Misri J, Sankar M (2015) Status of benzimidazole resistance in Haemonchus contortus of goats from different geographic regions of Uttar Pradesh, India. Vet Parasitol 208(3–4):263–267

    CAS  PubMed  Google Scholar 

  • Charles TP, Furlong JA (1996) Survey of dairy cattle worm control practices in southeast Brazil. Vet Parasitol 65(1–2):65–73

    CAS  PubMed  Google Scholar 

  • Chigure GM, Sharma AK, Kumar S, Fular A, Sagar SV, Nagar G, Upadhaya D, Saravanan BC, Kumar R, Ghosh S (2018) Role of metabolic enzymes in conferring resistance to synthetic pyrethroids, organophosphates, and phenylpyrazole compounds in Rhipicephalus microplus. Int J Acarology 44(1):28–34

    Google Scholar 

  • Dutta S, Godara R, Katoch R, Yadav A, Katoch M, Singh NK (2017) Detection of amitraz and malathion resistance in field populations of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) in Jammu region of India. Exp Appl Acarol 71:291–301

    CAS  PubMed  Google Scholar 

  • Economic survey (2021–22) Department of Economic Affairs, Ministry of Finance. Government of India

  • Escribano M, San Andres MI, de Lucas JJ, González-Canga A (2012) Ivermectin residue depletion in food producing species and its presence in animal foodstuffs with a view to human safety. Curr Pharm Biotechnol 13(6):987–98

    CAS  PubMed  Google Scholar 

  • FAO (2004) Ticks: Acaricide resistance, diagnosis, management and prevention. In: Resistance Management and Integrated Parasite Control in Ruminants: Guidelines Module 1. Animal Production and Health Division, Food and Agriculture Organization of the United Nations, Rome 25–77

  • Garg R, Yadav CL (2009) Genotyping of benzimidazole susceptible and resistant alleles in different populations of Haemonchus contortus from Himalayan and sub-Himalayan regions of North-West India. Trop Anim Health Prod 41:1127–1131

    PubMed  Google Scholar 

  • Gaur RS, Sangwan AK, Sangwan N, Kumar S (2016) Acaricide resistance in Rhipicephalus (Boophilus) microplus and Hyalomma anatolicum collected from Haryana and Rajasthan states of India. Exp Appl Acarol 69:487–500

    CAS  PubMed  Google Scholar 

  • George JE (2000) Present and future technologies for tick control. Ann N Y Acad Sci 916(1):583–588

    CAS  PubMed  Google Scholar 

  • Ghalsasi PP, Saste SR, Ghalsasi PM, Nimbkar C (2012) Emergence of benzimidazole resistance in nematodes of small ruminants in an organized farm and some smallholder flocks in Phaltan Taluka, Maharashtra. J Vet Parasitol 26(2):95–98

    Google Scholar 

  • Ghosh S, Azhahianambi P, de la Fuente J (2006) Control of ticks of ruminants, with special emphasis on livestock farming systems in India: present and future possibilities for integrated control—a review. Exp Appl Acarol 40:49–66

    CAS  PubMed  Google Scholar 

  • Gopi R, Narmatha N, Sakthivel KM, Uma V, Jothilakshmi M (2017) Socio-economic characteristics and its relationship with information seeking pattern of dairy farmers in Tamilnadu, India. Asian J Dairy Food Res 36(1):16–20

    Google Scholar 

  • Graf JF, Gogolewski R, Leach-Bing N, Sabatini GA, Molento MB, Bordin EL, Arantes GJ (2004) Tick control: an industry point of view. Parasitology 129(S1):S427–S442

    PubMed  Google Scholar 

  • Hoglund J, Dahlström F, Sollenberg S, Hessle A (2013) Weight gain-based targeted selective treatments (TST) of gastrointestinal nematodes in first-season grazing cattle. Vet Parasitol 196(3–4):358–365

    PubMed  Google Scholar 

  • Hou B, Yong R, Wuen J, Zhang Y, Buyin B, Subu D, Zha H, Li H, Hasi S (2022) Positivity rate investigation and anthelmintic resistance analysis of gastrointestinal nematodes in sheep and cattle in Ordos. China Animals 12(7):891

    PubMed  Google Scholar 

  • Jyothimol G, Ravindran R, Juliet S, Ajithkumar KG, Suresh NN, Vimalkumar MB, Lenka DR, Varghese S, Ghosh S (2014) Low level deltamethrin resistance in ticks from cattle of Kerala, a south Indian state. Vet Parasitol 204(3–4):433–438

    CAS  PubMed  Google Scholar 

  • Karthik D, Devi MC, Subash S, Dixit PK, Ramesha KP, Jayaraj Rao K, Sivaram M (2021) Profile characteristics of youth in dairying in Telangana state, India. Small (upto 5 members) 138:62–73

    Google Scholar 

  • Kerlinger FN (1973) Foundations of behavioural research. Surjeet Publication

    Google Scholar 

  • Keyyu JD, Kassuku AA, Msalilwa LP, Monrad J, Kyvsgaard NC (2006) Cross-sectional prevalence of helminth infections in cattle on traditional, small-scale and large-scale dairy farms in Iringa district, Tanzania. Vet Res Commun 30:45–55

    CAS  PubMed  Google Scholar 

  • Klafke G, Webster A, Agnol BD, Pradel E, Silva J, de La Canal LH et al (2017) Multiple resistance to acaricides in field populations of Rhipicephalus microplus from Rio Grande do Sul state, Southern Brazil. Ticks Tick-Borne Dis 8(1):73–80

    PubMed  Google Scholar 

  • Kumar S, Sharma AK, Nagar G, Rawat SS, Tiwari SS et al (2016) Characterization of acaricide resistance in tick isolates collected from Rajasthan, India. Indian J Anim Sci 86(1):14–23

    Google Scholar 

  • Lenka DR, Ravindran R, Jyothimol G, Udaykumar M et al (2016) Deltamethrin resistance in south Indian isolates of Rhipicephalus (Boophilus) microplus. Vet Parasitol: Reg Stud Rep 5:37–41

    CAS  Google Scholar 

  • Lopes LB, Nicolino R, Capanema RO, Oliveira CS, Haddad JP, Eckstein C (2015) Economic impacts of parasitic diseases in cattle. CABI Rev 1–0. In CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition, 10(51)

  • Malsawmdawngliana R, Rahman S (2016) Management practices followed by the dairy farmers of Mizoram, India. J Livest Sci 7:220–225

    Google Scholar 

  • Maqbool I, Wani ZA, Shahardar RA, Allaie IM, Shah MM (2017) Integrated parasite management with special reference to gastro-intestinal nematodes. J Parasit Dis 41(1):1–8

    CAS  PubMed  Google Scholar 

  • Mavrogianni VS, Papadopoulos E, Fragkou IA et al (2011) Administration of a long-acting antiparasitic to pre-pubertal ewe-lambs in Greece results in earlier reproductive activity and improved reproductive performance. Vet Parasitol 177(1–2):139–144

    CAS  PubMed  Google Scholar 

  • Meena RK, Swarnkar CP, Rathore B, Saini P, Meena AK (2022) Prevalence of anthelmintic resistance in gastrointestinal nematodes of goats of semi-arid Rajasthan. Pharma Innov J 11(5):1080–1086

    Google Scholar 

  • Melgar MJ, Santaeufemia M, Garcia MA (2010) Organophosphorus pesticide residues in raw milk and infant formulas from Spanish northwest. J Environ Sci Health B 45(7):595–600

    CAS  PubMed  Google Scholar 

  • Murcia P, Donachie W, Palmarini M (2009) Viral pathogens of domestic animals and their impact on biology, medicine and agriculture. Encycl Microbiol 805

  • Mutavi F, Heitkönig I, Wieland B, Aarts N, Van Paassen A (2021) Tick treatment practices in the field: access to, knowledge about, and on-farm use of acaricides in Laikipia, Kenya. Ticks Tick-Borne Dis 12(5):101757

    PubMed  Google Scholar 

  • Nandi A, Singh H, Singh NK, Rath SS (2018) Fenvalerate resistance status in Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) from Punjab, India. J Parasit Dis 40:694–698

    Google Scholar 

  • Narladkar BW (2018) Projected economic losses due to vector and vector-borne parasitic diseases in livestock of India and its significance in implementing the concept of integrated practices for vector management. Veterinary World 11(2):151–160

    CAS  PubMed  PubMed Central  Google Scholar 

  • National Action Plan for dairy development (NAPDD)-VISION (2022) National Dairy Development Board (NDDB), Government of India

  • Nielsen MK, Reist M, Kaplan RM, Pfister K, Van Doorn DC, Becher A (2014) Equine parasite control under prescription-only conditions in Denmark-Awareness, knowledge, perception, and strategies applied. Vet Parasitol 204(1–2):64–72

    CAS  PubMed  Google Scholar 

  • Nixon SA, Welz C, Woods DJ, Costa-Junior L, Zamanian M, Martin RJ (2020) Where are all the anthelmintics? Challenges and opportunities on the path to new anthelmintics. Int J Parasitol Drugs Drug Resist 14:8–16

    PubMed  PubMed Central  Google Scholar 

  • Obaid MK, Islam N, Alouffi A, Khan AZ, da Silva Vaz I Jr, Tanaka T, Ali A (2022) Acaricides resistance in ticks: selection, diagnosis, mechanisms, and mitigation. Front Cell Infect Microbiol 12:83–94

    Google Scholar 

  • Olatoye IO, Daniel OF, Ishola SA (2016) Screening of antibiotics and chemical analysis of penicillin residue in fresh milk and traditional dairy products in Oyo state, Nigeria. Vet World 9:948–954

    CAS  PubMed  PubMed Central  Google Scholar 

  • Ozturk Y, Celik S, Sahin E, Acik MN, Cetinkaya B (2019) Assessment of farmers’ knowledge, attitudes and practices on antibiotics and antimicrobial resistance. Animals 9(9):653

    PubMed  PubMed Central  Google Scholar 

  • Panda P (2021) Improvement of Biosecurity and Biosafety Measures in Livestock and Poultry farms using Android Mobile App: An Experimental Study. Thesis, Doctoral of Philosophy IVRI, Izatnagar, Bareilly, India

  • Patel P, Chauhan H, Srivastava A, Ankuya K, Prajapati R, Paregi A, Gupta JP (2018) Healthcare management practices followed by dairy farmers of Aravalli District of North Gujarat. Int J Curr Microbiol App Sc 7(11):1129–1135

    Google Scholar 

  • Patel PK, Shukla SN, Singh G (2020) Incidence of delayed puberty in Cattle Heifers in and around Jabalpur. Int J Curr Microbiol App Sci 9(06):1289–1292

    Google Scholar 

  • Rajdurai A, Rajganapathy V, Ganesan R et al (2018) Socio-economic profile of dairy farmers in Puducherry. Int J Adv Res Bio Sci 5(2):91–95

    Google Scholar 

  • Rathore RS, Singh R, Kachwaha RN, Kumar R (2010) Existing management practices followed by the cattle keepers in Churu district of Rajasthan. Indian J Anim Sci 80(8):798–805

    Google Scholar 

  • Reck J, Klafke GM, Webster A, Dall’Agnol B et al (2014) First report of fluazuron resistance in Rhipicephalus microplus: a field tick population resistant to six classes of acaricides. Vet Parasitol 201(1–2):128–36

    CAS  PubMed  Google Scholar 

  • Sadeghi H, Borji H (2015) A survey of intestinal parasites in a population in Qazvin, north of Iran. Asian Pac J Trop Dis 5(3):231–233

    Google Scholar 

  • Sagar SV, Saini K, Sharma AK, Kumar S, Kumar R, Fular A et al (2020) Acaricide resistance in Rhipicephalus microplus collected from selected districts of Madhya Pradesh, Uttar Pradesh and Punjab states of India. Trop Anim Health Prod 52:611–618

    PubMed  Google Scholar 

  • Samal L, Pattanaik AK (2013) Dairy production in India-existing scenario and future prospects. Int J Livest Res 4(2):105–113

    Google Scholar 

  • Sazmand A, Alipoor G, Zafari S, Zolhavarieh SM, Alanazi AD, Sargison ND (2020) Assessment of knowledge, attitudes and practices relating to parasitic diseases and anthelmintic resistance among livestock farmers in Hamedan, Iran. Front Vet Sci 7:584323

    PubMed  PubMed Central  Google Scholar 

  • Scott H, Jelinski M, Luby C, Uehlinger F (2019) Endoparasite control practices on Saskatchewan dairy farms. Can Vet J 60(6):613–618

    PubMed  PubMed Central  Google Scholar 

  • Selemetas N, Phelan P, O’Kiely P, de Waal T (2015) The effects of farm management practices on liver fluke prevalence and the current internal parasite control measures employed on Irish dairy farms. Vet Parasitol 207(3–4):228–240

    PubMed  Google Scholar 

  • Shalaby A (2013) Anthelmintic resistance; how to overcome it? Iran J Parasitoly 8(1):18–32

    Google Scholar 

  • Sharma KML (1984) Studies on certain aspects of the tick fauna of some of the mammalian hosts of economic importance and their carrier status of microbes. Ph.D. Thesis C.S.Azad, University of Agriculture and Technology, Kanpur 1–338

  • Sharma AK, Kumar R, Kumar S, Nagar G et al (2012) Deltamethrin and cypermethrin resistance status of Rhipicephalus (Boophilus) microplus collected from six agro-climatic regions of India. Vet Parasitol 188(3–4):337–345

    CAS  PubMed  Google Scholar 

  • Sharma M, Sangwan SS, Ahuja R, Ramkaran (2020) Impact of scientific dairy farming trainings on farmer’s knowledge about management practices. Int J Curr Microbiol App Sci 9(5):1746–1752

    Google Scholar 

  • Siddiki AZ, Uddin MB, Hasan MB, Hossain MF et al (2010) Coproscopic and Haematological Approaches to Determine the Prevalence of Helminthiasis and Protozoan Diseases of Red Chittagong Cattle (RCC) Breed in Bangladesh. Pak Vet J 30(1):1–6

    Google Scholar 

  • Singh N, Malhotra P, Singh J (2016) Information needs and seeking behaviour of dairy farmers of Punjab. Indian J Dairy Sci 69(1):98–104

    Google Scholar 

  • Singh A, Tiwari R, Panda P, Dutt T (2020) Organic waste production and utilization by dairy farmers in district Ludhiana of Punjab, India. Indian J Ext Educ 56(1):20–27

    Google Scholar 

  • Singh A, Tiwari R, Panda P, Gaur G, Dutt T (2022) Information source utilization for organic waste management with special reference to digital technologies: a qualitative study on dairy farmers of district Ludhiana, Punjab. Cogent Educ 9(1):2062093

    Google Scholar 

  • Singodia M, Rewani SK, Baindha A, Chand S, Rajoria S, Singh V (2019) Constraints faced by livestock farmers in utilization of livestock services in Jaipur district of Rajasthan, India. Indian Res J Ext Educ 19:104–107

    Google Scholar 

  • Soulsby EJL (2006) Helminths, arthropods and protozoa of domesticated animals, 7th edn. Bailliere Tindall and Cassel Ltd., London, pp 444–475

    Google Scholar 

  • Sutherland IA, Leathwick DM (2011) Anthelmintic resistance in nematode parasites of cattle: a global issue? Trends Parasitol 27(4):176–181

    PubMed  Google Scholar 

  • Tiwari J, Kumar S, Kolte AP, Swarnkar CP, Singh D, Pathak KM (2006) Detection of benzimidazole resistance in Haemonchus contortus using RFLP-PCR technique. Vet Parasitol 138(3–4):301–307

    CAS  PubMed  Google Scholar 

  • Tufa TB, Gurmu F, Beyi AF, Hogeveen H, Beyene TJ et al (2018) Veterinary medicinal product usage among food animal producers and its health implications in Central Ethiopia. BMC Vet Res 14:1–7

    Google Scholar 

  • Van Wyk JA (2001) Refugia-Overlooked as perhaps the most potent factor concerning the development of anthelmintic resistance. Underreport J Vet Res 68:55–67

    Google Scholar 

  • WHO (2000) Guidelines for the regulatory assessment of medicinal products for use in self-medication. World Health Organization. https://iris.who.int/handle/10665/66154

  • Wood S, Reyher KK, Barrett DC (2015) Comparison of visual assessment and heart girth tape measurement for estimating the weight of cattle in clinical practice. Vet J 203(3):337–338

    PubMed  Google Scholar 

  • Yadav CL, Uppal RP, Kalra S (1993) An outbreak of haemonchosis associated with anthelmintic resistance in sheep. Int J Parasitol 23(3):411–413

    CAS  PubMed  Google Scholar 

  • Zacarias Do Amaral MA, Christiane M, Rocha MB et al (2011) Perceptions and attitudes among milk producers in Minas Gerais regarding cattle tick biology and control. Rev Bras Parasitol Vet 20(3):194–201

    Google Scholar 

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Authors and Affiliations

  1. Division of Extension Education, ICAR-Indian Veterinary Research Institute, Izzatnagar, 243122, Uttar Pradesh, India

    Maina Kumari & Amol Patil

  2. ICAR-Indian Veterinary Research Institute, Izzatnagar, 243122, Uttar Pradesh, India

    Rupasi Tiwari

  3. Division of Parasitology, ICAR-Indian Veterinary Research Institute, Mukteswar, 263138, Uttarakhand, India

    Ashutosh Fular

  4. Rampuraphul, India

    Pratikshya Panda

  5. ICAR- Indian Veterinary Research Institute, Izzatnagar, 243122, Uttar Pradesh, India

    Triveni Dutt

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  1. Maina Kumari
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Contributions

1. Dr. Maina Kumari was the Principal Investigator of the research work and dealt with all the budgetary and human resource allocations and sanctions. 2. Dr. Rupasi Tiwari was the Chairperson, student advisory committee and research guide. 3. Dr. Ashutosh Fular, Dr. Amol Patil, and Dr. Pratikshya Panda dealt with data analysis and scripting. 4. Dr. Triveni Dutt was member of the student advisory committee.

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Kumari, M., Tiwari, R., Fular, A. et al. Assessing the utilization patterns of antiparasitic drug and farmer’s perception: implications for resistance in India's dairy farming sector. Int J Trop Insect Sci 44, 913–930 (2024). https://doi.org/10.1007/s42690-024-01195-8

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