Abstract
Hemoglobinopathies including thalassemias are among the most frequent genetic disorders worldwide. Primarily, these entities result from germline variants in the globin gene clusters and their cis-acting regulatory elements, and thus the WHO classifies thalassemias as inherited diseases. Non-inherited disorders of globin chain synthesis mimicking the phenotype of thalassemias have also been described and are referred to as acquired thalassemias. These forms mainly affect the alpha-globin genes and are observed at much lower frequencies...
Figures & Tables
Article Information
Pubmed
Published
2024-03-14
Published By
Ferrata Storti Foundation, Pavia, Italy
Print ISSN
0390-6078
Online ISSN
1592-8721
Copyright & Usage
Copyright (c) 2024 Ferrata Storti Foundation
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Article Usage
Online Views
215
PDF Downloads
124
Statistics from Altmetric.com
No Data