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Preparation of Substituted gem-Dichlorocyclopropanes and 1,3-Dioxacycloalkanes and Their Biological Activity: A Review

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Abstract―

This work generalizes methods for preparation of basic platform compounds, namely, hem-dichlorocyclopropanes and 1,3-dioxacycloalkanes with various substituents. On their basis, the synthesis of carbo- and heterocyclic compounds is carried out, which have herbicidal, cytotoxic, anticoagulant and antiaggregation properties and are of interest in terms of creating new pesticides for dicotyledonous and monocotyledonous plants, drugs that prevent blood clotting or inhibit the development of tumor cells.

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REFERENCES

  1. Kazakova, A.N., Timofeeva, S.A., Yumakaeva, Yu.M., Khairullina, A.F., and Zlotskii, S.S., Bashk. Khim. Zh., 2010, vol. 17, no. 4, p. 19.

    CAS  Google Scholar 

  2. Raskil’dina, G.Z., Valiev, V.F., and Zlotskii, S.S., Russ. J. Appl. Chem., 2016, vol. 89, no. 5, p. 753.

    Article  Google Scholar 

  3. Raskil’dina, G.Z., Kuzmina, U.Sh., Dzhumaev, Sh.Sh., Borisova, Yu.G., Ishmetova, D.V., Vakhitova, Yu.V., and Zlotskii, S.S., Russ. Chem. Bull., 2021, vol. 70, no. 3, p. 475.

    Article  Google Scholar 

  4. Raskil’dina, G.Z., Borisova, Yu.G., Valiev, V.F., Mikhailova, N.N., Zlotskii, S.S., Zaikov, G.E., and Emelina, O.Yu., Vestn. Kazan. Tekhnol. Univ., 2014, no. 17, p. 166.

  5. Valiev, V.F., Raskil’dina, G.Z., Mudrik, T.P., Bogomazova, A.A., and Zlotskii, S.S., Bashk. Khim. Zh., 2014, vol. 21, no. 3, p. 25.

    CAS  Google Scholar 

  6. Sakhabutdinova, G.N., Raskil’dina, G.Z., Chanyshev, R.R., and Zlotskii, S.S., Bashk. Khim. Zh., 2020, vol. 27, no. 1, p. 22.

    Google Scholar 

  7. Raskildina, G.Z., Borisova, Yu.G., Dzhumaev, Sh.Sh., and Zlotskii, S.S., Russ. J. Gen. Chem., 2019, vol. 89, no. 12, p. 2341.

    Article  CAS  Google Scholar 

  8. Raskil’dina, G.Z., Sultanova, R.M., and Zlotskii, S.S., Izv. Ufimsk. Nauchn. Tsentra Ross. Akad. Nauk, 2019, no. 3, p. 5.

  9. Raskil’dina, G.Z., Yakovenko, E.A., Mryasova, L.M., and Zlotskii, S.S., Izv. Vyssh. Uchebn. Zaved., Khim. Khim. Tekhnol., 2019, vol. 62, no. 1, p. 91.

    Article  Google Scholar 

  10. Dzhumaev, Sh.Sh., Borisova, Yu.G., Shavshukova, S.Yu., and Raskil’dina, G.Z., Bashk. Khim. Zh., 2019, vol. 26, no. 2, p. 25.

    CAS  Google Scholar 

  11. Raskil’dina, G.Z., Sultanova, R.M., and Zlotskii, S.S., Rev. Adv. Chem., 2023, vol. 13, p. 15.

    Article  Google Scholar 

  12. Mohammed, H.K., Al-Bakrib, A., Saadeha, H., and Al-Hiari, Y.M., Jordan J. Chem., 2012, vol. 7, no. 3, p. 239.

    Google Scholar 

  13. Dzhumaev, Sh.Sh., Borisova, Yu.G., Raskil’dina, G.Z., and Zlotskii, S.S., Chem. Technol. Org. Subst., 2020, vol. 3, no. 15, p. 4.

    Article  Google Scholar 

  14. Raskil’dina, G.Z., Valiev, V.F., Sultanova, R.M., and Zlotsky, S.S., Russ. J. Appl. Chem., 2015, vol. 88, no. 10, p. 1414.

    Article  Google Scholar 

  15. Sakhabutdinova G.N., Yakovenko, E.A., Raskil’dina, G.Z., and Zlotskii, S.S., Russ. J. Appl. Chem., 2020, vol. 93., no. 7, p. 967.

    Article  CAS  Google Scholar 

  16. Raskil’dina, G.Z., Dzhumaev, Sh.Sh., Borisova, Yu.G., Spirikhin, L.V., and Zlotskii, S.S., Russ. J. Gen. Chem., 2020, vol. 90, no. 1, p. 1.

    Article  Google Scholar 

  17. Stepanova, L.B., Nafikova, R.F., and Deberdeev, T.R., Vestn. Kazan. Tekhnol. Univ., 2013, vol. 16, no. 9, p. 101.

    CAS  Google Scholar 

  18. Musin, A.I., Borisova, Yu.G., Raskil’dina, G.Z., Spirikhin, L.V., Sultanova, R.M., and Zlotskii, S.S., Izv. Vyssh. Uchebn. Zaved., Khim. Khim. Tekhnol., 2023, vol. 66, no. 9, p. 20.

    CAS  Google Scholar 

  19. Orth, H., Angew. Chem., 1952, vol. 64, nos. 19–20, p. 544.

    Article  CAS  Google Scholar 

  20. Sokov, A.A., Borisova, Yu.G., Raskil’dina, G.Z., Zlotskii, S.S., and Golovanov, A.A., Russ. J. Gen. Chem., 2023, vol. 93, no. 10, p. 2493.

    Article  CAS  Google Scholar 

  21. Brandsma, L., Synthesis of Acetylenes, Allenes and Cumulenes, Amsterdam: Elsevier, 2004.

    Google Scholar 

  22. Mirakyan, S.M., Raskil’dina, G.Z., Valiev, V.F., Chanyshev, R.R., and Zlotskii, S.S., Izv. Vyssh. Uchebn. Zaved., Khim. Khim. Tekhnol., 2017, vol. 60, no. 10, p. 16.

    Google Scholar 

  23. Musin, A.I., Sultanova, D.S., Borisova, Yu.G., Mudrik, T.P., and Daminev, R.R., Tonk. Khim. Tekhnol., 2023, vol. 18, no. 1, p. 21.

    CAS  Google Scholar 

  24. Chaffey, D.R., Davies, T.E., Taylor, S.H., and Graham, A.E., ACS Sustainable Chem. Eng., 2018, vol. 6, no. 4, p. 4996.

    Article  CAS  Google Scholar 

  25. Borisova, Yu.G., Dzhumaev, Sh.Sh., Islamutdinova, A.A., Valitova, E.G., and Mudrik, T.P., Bashk. Khim. Zh., 2022, vol. 29, no. 1, p. 11.

    CAS  Google Scholar 

  26. Oparina, L.A., Vysotskaya, O.V., Stepanov, A.V., Gusarova, N.K., and Trofimov, B.A., Russ. J. Org. Chem., 2012, vol. 48, no. 9, pp. 1162.

    Article  CAS  Google Scholar 

  27. Musin, A.I. and Borisova, Yu.G., Raskil’dina, G.Z., Daminev, R.R., Rabaev, R.U., and Zlotskii, S.S., Fine Chem. Technol., 2020, vol. 15, no. 6, p. 9.

    Article  CAS  Google Scholar 

  28. Borisova, Y.G., Yakupov, N.V., Raskildina, G.Z., Zlotskii, S.S., Musin, A.I., and Daminev, R.R., Russ. J. Gen. Chem., 2021, vol. 91, no. 9, p. 1619.

    Article  Google Scholar 

  29. Musin, A.I., Borisova, Yu.G., Raskil’dina, G.Z., Daminev, R.R., Davletshin, A.R., and Zlotskii, S.S., Fine Chem. Technol., 2022, vol. 17, no. 3, p. 201.

    Article  Google Scholar 

  30. Yakovenko, E.A., Baimurzina, Yu.L., Raskil’dina, G.Z., and Zlotskii, S.S., Russ. J. Appl. Chem., 2020, vol. 93, no. 5, p. 712.

    Article  CAS  Google Scholar 

  31. Kuz’mina, U.S., Raskil’dina, G.Z., and Ishmetova, D.V., Pharm. Chem. J., 2022, no. 55, p. 1293.

  32. Melnikov, A.S., Meshcheryakova, S.A., Abzalilov, T.A., and Nurlanova, S.N., Med.-Farm. Zh. Pulse, 2021, vol. 23, p. 6.

    Google Scholar 

  33. Raskil’dina, G.Z., Borisova, Yu.G., Nurlanova, S.N., Bashirov, I.I., Fahretdinova, A.K., Purygin, P.P., Zlotsky, S.S., and Zarubin, Yu.P., Butlerov Commun., 2022, vol. 70, no. 5, p. 86.

    Google Scholar 

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Funding

This work was supported by the Budget of the Republic of Bashkortostan for State support of young scientists (order no. 2987 dated November 29, 2022) on the topic “Catalytic reduction of heterocyclic ketones as a new method for the preparation of petrochemical polyols and small-scale products.”

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Authors and Affiliations

  1. Ufa State Petroleum Technological University, 450062, Ufa, Russia

    G. Z. Raskil’dina, A. I. Musin, Yu. G. Borisova, R. M. Sultanova, R. R. Daminev & S. S. Zlotskii

Authors
  1. G. Z. Raskil’dina
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  2. A. I. Musin
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  3. Yu. G. Borisova
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  4. R. M. Sultanova
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  5. R. R. Daminev
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  6. S. S. Zlotskii
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Correspondence to Yu. G. Borisova or S. S. Zlotskii.

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Raskil’dina, G.Z., Musin, A.I., Borisova, Y.G. et al. Preparation of Substituted gem-Dichlorocyclopropanes and 1,3-Dioxacycloalkanes and Their Biological Activity: A Review. rev. and adv. in chem. 13, 443–453 (2023). https://doi.org/10.1134/S263482762460004X

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  • DOI: https://doi.org/10.1134/S263482762460004X

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