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Advanced Interventional Treatments in Retinoblastoma Management: A Comprehensive Review

  • Review
  • Interventional Oncology
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CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Retinoblastoma is the most common eye malignancy in children that if left untreated can invade intraocular structures, metastasize, and rarely lead to death. Traditionally treated with systemic chemotherapy, Intra-arterial chemotherapy is gaining popularity as it allows for the direct administration of chemotherapy through the ophthalmic artery, thus reducing systemic side effects. Intra-arterial chemotherapy procedures have evolved, with refinements to reduce risks and radiation exposure. Intra-arterial chemotherapy boasts an impressive technical success rate and one year ocular survival even amongst advanced cases. This review offers a thorough examination of the technique, indications, contraindications, outcomes, and alternative options for Intra-arterial chemotherapy.

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Authors and Affiliations

  1. Department of Radiology, Georgetown University School of Medicine, Washington, USA

    Peter Kolyvas, Aazrin Mir, Thomas Stirrat, Brittany Brookner & Nathanael Pilar

  2. Department of Radiology, University of Wisconsin, Madison, USA

    Eric Monroe

  3. McGovern Medical School, Diagnostic and Interventional Radiology, The University of Texas Health Science Center Houston, Houston, USA

    Rakesh Ahuja

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  1. Peter Kolyvas
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Correspondence to Peter Kolyvas.

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Kolyvas, P., Mir, A., Stirrat, T. et al. Advanced Interventional Treatments in Retinoblastoma Management: A Comprehensive Review. Cardiovasc Intervent Radiol 47, 407–415 (2024). https://doi.org/10.1007/s00270-024-03692-2

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