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Electrochemically selective detection of dopamine over serotonin by CuO/Cu2O bulk heterostructure electrode

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Abstract

A facile single-pot electrochemical technique was adopted to deposit CuO/Cu2O bulk heterostructure in the form of thin film on indium-doped tin oxide (ITO)-coated glass substrates aiming to explore its non-enzymatic electrochemical sensing performance of the two neurotransmitters, viz. dopamine (DA) and serotonin (ST). Thorough structural characterization of the deposited materials was carried out, followed by detailed electrochemical analyses towards the sensing of dopamine and serotonin in phosphate buffer solution. The sensitivity of the electrode was found to be 9.22 µA µM−1 cm−2 with a limit of detection (LoD) of 0.388 µM for dopamine. Whereas for serotonin, the sensitivity and LoD values were 1.18 µA µM−1 cm−2 and 8.11 µM, respectively. The results clearly indicates that the CuO/Cu2O bulk heterostructure electrode is a better candidate for the electrochemical detection of dopamine, whereas its serotonin sensitivity was average. This makes the electrode more selective to dopamine.

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Acknowledgements

NM and BS acknowledge the Department of Higher Education, Science and Technology and Biotechnology, Government of West Bengal, India, for financial support through research grant #ST/P/S&T/16G-49/2017.

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Authors and Affiliations

  1. Nanoscience Laboratory, Department of Physics, Aliah University, IIA/27 Newtown, Kolkata, 700160, India

    Rimpa Mondal & Sk. Faruque Ahmed

  2. Department of Chemistry, Jadavpur University, Kolkata, 700032, India

    Bibhutibhushan Show

  3. School of Advanced Materials, Green Energy and Sensor Systems, Indian Institute of Engineering Science and Technology, Shibpur, Howrah, 711103, India

    Rimpa Mondal & Nillohit Mukherjee

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  1. Rimpa Mondal
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  2. Bibhutibhushan Show
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Correspondence to Nillohit Mukherjee.

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Mondal, R., Show, B., Ahmed, S. et al. Electrochemically selective detection of dopamine over serotonin by CuO/Cu2O bulk heterostructure electrode. Bull Mater Sci 47, 62 (2024). https://doi.org/10.1007/s12034-023-03131-x

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