Issue 32, 2024

Synthesis of two nitrogen-containing polyaromatic compounds through gold catalysis/DBU-promoted cyclizations

Abstract

This work reports an efficient synthesis of novel benzo[7,8]indolizino[2,3,4,5-ija]quinazoline derivatives between 2-(2-ethynylaryl)acetonitriles 1 and anthranils 2. The synthetic approach involves the initial formation of 7-formylindole intermediates that can be implemented by DBU to activate a novel indole–nitrile–aldehyde cyclization.

Graphical abstract: Synthesis of two nitrogen-containing polyaromatic compounds through gold catalysis/DBU-promoted cyclizations

Supplementary files

Article information

Article type
Communication
Submitted
09 Jan 2024
Accepted
19 Mar 2024
First published
25 Mar 2024
This article is Open Access
Creative Commons BY license

Chem. Commun., 2024,60, 4294-4297

Synthesis of two nitrogen-containing polyaromatic compounds through gold catalysis/DBU-promoted cyclizations

V. A. Sadaphal, T. Wu and R. Liu, Chem. Commun., 2024, 60, 4294 DOI: 10.1039/D4CC00113C

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