Skip to main content
SpringerLink
Log in

Layer-by-Layer Deposition of Chitosan/Hyaluronic Acid Polyelectrolyte Complex Coatings onto Polyester Films

  • MEDICAL POLYMERS
  • Published:
Polymer Science, Series A Aims and scope Submit manuscript

Abstract

The surface modification of polycaprolactone and polycaprolactone/polylactide mixed films was carried out by preliminary surface activation in NaOH. Subsequent layer-by-layer deposition of coatings based on polyelectrolyte complexes of the oppositely charged polysaccharides: chitosan and hyaluronic acid, was carried out. The effect of surface activation was studied using contact angle measurements, surface analysis and gravimetric data. The characterization of the polyelectrolyte complex coatings using gravimetric analysis, goniometric and micrometer measurements, scanning electron, optical and fluorescence microscopy, and FTIR-ATR spectroscopy confirmed the formation of a uniform coating with a thickness of about 30 μm, which is not prone to peeling from the substrate.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.
Fig. 6.
Fig. 7.
Fig. 8.
Fig. 9.

REFERENCES

  1. S. Liu, S. Qin, M. He, D. Zhou, Q. Qin, and H. Wang, Composites, Part B 199, 108238 (2020).

    Article  CAS  Google Scholar 

  2. M. A. Woodruff and D. W. Hutmacher, Prog. Polym. Sci. 35, 1217 (2010).

    Article  CAS  Google Scholar 

  3. Y. Bu, J. Ma, J. Dei, and S. Wang, Front. Bioeng. Biotechnol. 7, 98 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  4. S. G. Kou, L. Peters, and M. Mucalo, Carbohydr. Polym. 282, 119132 (2022).

    Article  CAS  PubMed  Google Scholar 

  5. T. S. Demina, A. A. Frolova, A. V. Istomin, S. L. Kotova, M. S. Piskarev, K. N. Bardakova, M. Yu. Yablokov, V. A. Altynov, L. I. Kravets, A. B. Gilman, T. A. Akopova, and P. S. Timashev, J. Appl. Polym. Sci. 137, 48287 (2020).

    Article  CAS  Google Scholar 

  6. M. F. P. Graça, S. P. Miguel, C. S. D. Cabral, and I. J. Correia, Carbohydr. Polym. 241, 116364 (2020).

    Article  PubMed  Google Scholar 

  7. M. N. Collins and C. Birkinshaw, Carbohydr. Polym. 92, 1262 (2013).

    Article  CAS  PubMed  Google Scholar 

  8. C. E. Garcia Garcia, F. A. Soltero Martínez, F. Bossard, and M. Rinaudo, Polymers 12, 2004 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  9. M. G. Drozdova, T. S. Demina, O. A. Dregval, A. I. Gaidar, E. R. Andreeva, A. N. Zelenetskii, T. A. Akopova, and E. Markvicheva, Polysaccharides 3, 745 (2022).

    Article  CAS  Google Scholar 

  10. S. I. Goreninskii, R. O. Guliaev, K. S. Stankevich, N. V. Danilenko, E. N. Bolbasov, A. S. Golovkin, A. I. Mishanin, V. D. Filimonov, and S. I. Tverdokhlebov, Colloid. Surf., B 177, 137 (2019).

  11. W. Chen, L. Nichols, F. Brinkley, K. Bohna, W. Tian, M. W. Priddy, and L. B. Priddy, Mater. Sci. Eng., C 120, 111686 (2021).

    Article  CAS  Google Scholar 

  12. H. Hartmann, S. Hossfeld, B. Schlosshauer, U. Mittnacht, A. P. Pêgo, M. Dauner, M. Doser, D. Stoll, and R. Krastev, J. Control. Release 168, 297 (2013).

    Article  Google Scholar 

  13. S. Zhang, M. Xing, and B. Li, Int. J. Mol. Sci. 19, 1641 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  14. W. Yuan, G.-M. Weng, J. Lipton, C. M. Li, P. R. Van Tassel, and A. D. Taylor, Adv. Colloid Interface Sci. 282, 102200 (2020).

    Article  CAS  PubMed  Google Scholar 

  15. A. Zhu, M. Zhang, J. Wu, and J. Shen, Biomaterials 23, 4665 (2002).

    Google Scholar 

  16. J. Andrade-Del Olmo, L. Pérez-Álvarez, E. Hernáez, L. Ruiz-Rubio, and J. L. Vilas-Vilela, Food Hydrocolloids 88, 228 (2019).

    Article  CAS  Google Scholar 

  17. J. Schoeller, F. Itel, K. Wuertz-Kozak, S. Gaiser, N. Luisier, D. Hegemann, S. J. Ferguson, G. Fortunato, and R. M. Rossi, Nanomaterials 11, 1850 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. A. Hautmann, D. Kedilaya, S. Stojanović, M. Radenković, C. K. Marx, S. Najman, M. Pietzsch, J. F. Mano, and T. Groth, Biomater. Adv. 142, 213166 (2022).

    Article  CAS  PubMed  Google Scholar 

  19. Y. Wang, B. Ma, A. Yin, B. Zhang, R. Luo, J. Pan, and Y. Wang, J. Control. Release 320, 226 (2020).

    Article  CAS  PubMed  Google Scholar 

  20. K. Kalinov, M. Ignatova, V. Maximova, I. Rashkov, and N. Manolova, Eur. Polym. J. 50,18 (2014).

    Article  CAS  Google Scholar 

  21. S. Maiz-Fernández, N. Barroso, L. Pérez-Álvarez, U. Silván, J. L. Vilas-Vilela, and S. Lanceros-Mendez, Int. J. Biol. Macromol. 188, 820 (2021).

    Article  PubMed  Google Scholar 

  22. C. Vasile, D. Pieptu, R. P. Dumitriu, A. Pânzariu, and L. Profire, Rev. Med. Chir. Soc. Med. Nat. Iasi. 117, 565 (2013).

    PubMed  Google Scholar 

  23. M. Drozdova, M. Vodyakova, T. Tolstova, M. Chernogortseva, N. Sazhnev, T. Demina, N. Aksenova, P. Timashev, N. Kildeeva, and E. Markvicheva, Polymers 15, 2371 (2023).

  24. S. V. Kononova, E. V. Kruchinina, V. A. Petrova, Y. G. Baklagina, V. V. Klechkovskaya, A. S. Orekhov, E. N. Vlasova, E. N. Popova, G. N. Gubanova, and Y. A. Skorik, Carbohydr. Polym. 209, 10 (2019).

    Article  CAS  PubMed  Google Scholar 

  25. H. Sun, D. Choi, J. Heo, S. Y. Jung, and J. Hong, Cancers 12, 593 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. F. I. Boni, B. S. F. Cury, N. N. Ferreira, D. A. Teixeira, and M. P. D. Gremião, Carbohydr. Polym. 254, 117444 (2021).

    Article  CAS  PubMed  Google Scholar 

  27. G. Ma, Y. Liu, D. Fang, J. Chen, C. Peng, X. Fei, and J. Nie, Mater. Lett. 74, 78 (2012).

    Article  CAS  Google Scholar 

  28. S. Del Hoyo-Gallego, L. Pérez-Álvarez, F. Gómez-Galván, E. Lizundia, I. Kuritka, V. Sedlarik, J. M. Laza, and J. L. Vila-Vilela, Carbohydr. Polym. 143, 35 (2016).

    Article  CAS  PubMed  Google Scholar 

  29. L. Pérez-Álvarez, E. Lizundia, S. del Hoyo, A. Sagasti, L. R. Rubio, and J. L. Vilas, Polym. Int. 65, 915 (2016).

    Article  Google Scholar 

  30. N. Barroso, O. Guaresti, L. Pérez-Álvarez, L. Ruiz-Rubio, N. Gabilondo, and J. L. Vilas-Vilela, Eur. Polym. J. 120, 109268 (2019).

    Article  CAS  Google Scholar 

  31. I. S. Chaschin, M. A. Sinolits, G. A. Badun, M. G. Chernysheva, N. M. Anuchina, S. V. Krasheninnikov, G. A. Khugaev, A. A. Petlenko, D. V. Britikov, A. V. Zubko, A. D. Kurilov, E. I. Dreger, and N. P. Bakuleva, Int. J. Biol. Macromol. B 222, 2761 (2022).

    Article  CAS  Google Scholar 

  32. S. Wu, Polymer Interface and Adhesion (M. Dekker, New York, 1982).

  33. M. Schönhoff, J. Phys. Condens. Matter. 15, R1781 (2003).

    Article  Google Scholar 

Download references

Funding

This work was supported by Ministry of Science and Higher Education of the Russian Federation (FFSM-2022-0001).

Author information

Authors and Affiliations

  1. Enikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences, 117393, Moscow, Russia

    A. V. Birdibekova, T. A. Akopova & T. S. Demina

  2. Moscow Aviation Institute (National Research University), 125993, Moscow, Russia

    E. A. Starostina & T. S. Demina

  3. Institute for Regenerative Medicine, Sechenov First Moscow State Medical University, 119991, Moscow, Russia

    A. S. Kuryanova, N. A. Aksenova & P. S. Timashev

  4. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, 119991, Moscow, Russia

    A. S. Kuryanova & N. A. Aksenova

  5. World-Class Research Center “Digital Biodesign and Personalized Healthcare”, Sechenov First Moscow State Medical University, 119991, Moscow, Russia

    T. S. Demina

Authors
  1. A. V. Birdibekova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. A. Starostina
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. S. Kuryanova
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. A. Aksenova
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. P. S. Timashev
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. T. A. Akopova
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. T. S. Demina
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Conceptualization, A.V.B. and T.S.D.; methodology, A.V.B. and E.A.S.; investigation, A.V.B., E.A.S., T.S.D., A.S.K. and N.A.A.; visualization, A.V.B.; writing—original draft preparation, A.V.B.; writing—review and editing, P.S.T., T.A.A. and T.S.D. All authors have read and agreed to the published version of the manuscript.

Corresponding author

Correspondence to T. S. Demina.

Ethics declarations

The authors declare that they have no conflict of interest.

Additional information

Publisher’s Note.

Pleiades Publishing remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Birdibekova, A.V., Starostina, E.A., Kuryanova, A.S. et al. Layer-by-Layer Deposition of Chitosan/Hyaluronic Acid Polyelectrolyte Complex Coatings onto Polyester Films. Polym. Sci. Ser. A 65, 672–681 (2023). https://doi.org/10.1134/S0965545X2460008X

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0965545X2460008X

Search

Navigation