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Gender Differences in Cannabis Outcomes After Recreational Cannabis Legalization: A United States Repeated Cross-sectional Study, 2008–2017

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Abstract

Cannabis use has been more prevalent among men than women and prior work has found differing impact of recreational cannabis laws (RCL) by age. We examined changes in the prevalence of past-year and past-month cannabis use, past-month daily cannabis use, and DSM-5-proxy cannabis use disorder (CUD) in the past-year before and after RCL enactment by gender alone and stratified by age using 2008–2017 repeated cross-sectional samples of the US National Survey on Drug Use and Health. Changes in cannabis outcomes were estimated using adjusted multi-level logistic regression with state random intercepts and two-way and three-way interactions between RCL, gender, and age group. Enactment of RCL was associated with higher increases in the past-year (+ 3.2%; aOR = 1.30 [95%CI = 1.19 to 1.41]) and past-month (+ 2.3; 1.37 [1.24 to 1.51]) cannabis use in women than men (+ 2.1%; 1.15 [1.06 to 1.25] and + 1.7%; 1.19 [1.08 to 1.30]). No increases in past-month daily cannabis use and past-year DSM-5 CUD among those using cannabis were observed after RCL enactment. There were no increases in any cannabis outcomes after RCL enactment among those 12–20 years old. RCL enactment may contribute to the narrowing of the cannabis gender gap. Ongoing surveillance is essential to ensure that the social justice aims of legalization are achieved without negative public health consequences.

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Funding

This study was funded by grants from the US National Institutes of Health, National Institute on Drug Abuse R01DA037866 (Martins), R01DA048860 (Hasin), K01DA045224 (P. Mauro), K01DA039804 (Philbin), T32DA031099 (Hasin & Martins).

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All authors have contributed significantly to the work and agree with the submission. Dr. Segura and Dr. Martins designed and conceptualized the study. Dr. C. M. Mauro directed Dr. Segura on the data analysis. Dr. Levy and Dr. Bruzelius contributed on running data analyses. Dr. Segura wrote the first full draft of the manuscript. Dr. Levy, Ms. Gutkind, and Dr. Segura conducted the literature review, and Dr. Segura prepared the “Methods” and “Results” sections of the text. Dr. Philbin, Dr. P. M. Mauro, Dr. Levy, Dr. Bruzelius, Ms. Gutkind, Dr. Hasin, Dr. P. M. Mauro, and Dr. Martins critically reviewed all sections of the manuscript. Dr. Segura is responsible for the overall content as guarantor and accepts full responsibility for the work and/or the conduct of the study, had access to the data, and controlled the decision to publish.

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Correspondence to Silvia S. Martins.

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All authors declare no conflict of interest.

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The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data, and preparation, review, or approval of this manuscript.

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Segura, L.E., Levy, N.S., Mauro, C.M. et al. Gender Differences in Cannabis Outcomes After Recreational Cannabis Legalization: A United States Repeated Cross-sectional Study, 2008–2017. Int J Ment Health Addiction (2024). https://doi.org/10.1007/s11469-024-01271-7

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  • DOI: https://doi.org/10.1007/s11469-024-01271-7

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