个人简介
毕业于华中科技大学生命科院，获生物物理专业博士学位，后在加拿大多伦多大学生理系进行博士后研究。主要领域为细胞分泌，蛋白质相互作用以及离子通道功能与疾病关联方面的研究。近年来发表多篇高质量论文，阐述了心脏病、糖尿病等相关的一些发病机理和分子机制，为将来彻底攻克这些疾病提供生物学基础。
近期论文
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1.LipingLiao,XianguangLin,JielinHu,XinWu,XiaofeiYang,WeiWangandChenhongLi.SIMULATIONANDCALCULATIONOFTHECONTRIBUTIONOFHYPERPOLARIZATION-ACTIVATEDCYCLICNUCLEOTIDE-GATEDCHANNELSTOACTIONPOTENTIALS.Arch.Biol.Sci.,Belgrade,68(1),217-224,2016.DOI:10.2298/ABS150416144L
2.XieL,LiangT,KangY,LinX,SobbiR,XieH,ChaoC,BackxP,FengZP,ShyngSL,GaisanoHY.Phosphatidylinositol4,5-biphosphate(PIP2)modulatessyntaxin-1Abindingtosulfonylureareceptor2AtoregulatecardiacATP-sensitivepotassium(KATP)channels.JMolCellCardiol.2014Oct;75:100-10.doi:10.1016/j.yjmcc
3.ChaoC,LiangT,KangY,LinX,XieH,FengZP,GaisanoHY.Syntaxin-1AinhibitsK(ATP)channelsbyinteractingwithspecificconservedmotifswithinsulfonylureareceptor2A.JMolCellCardiol.2011Nov;51(5):790-802.
4.ChangN,LiangT,LinX,KangY,XieH,FengZP,GaisanoHY.Syntaxin-1Ainteractswithdistinctdomainswithinnucleotide-Bindingfoldsofsulfonylureareceptor1toinhibitbeta-cellKATPchannels.JBiolChem.2011;May3;286(26):23308-18.
5.Xian-GuangLIN,Minming,YangXiao,YamingJiu,MaorongChen,Zheng-XingWuandTaoXu.UNC-31/CAPSdocksandprimesdensecorevesiclesinC.elegansneurons.BiochemBiophysResCommun.2010;Jul2;397(3):526-31.
6.Xian-GuangLIN,RecentAdvanceonFunctionofCAPSinVesicularExocytosis.ProgressinModernBiomedicine,2010;Vol.16.
7.DongYong-Ming,ZHANGMing,LINXian-Guang,ZHOUWei,XIELi,TheMechanismofCalciumSignalingRegulatingInsulinSecretion.ProgressinModernBiomedicine,2008;Vol.8,No.5,937-939.
8.ZHANGMing,LINXian-Guang,JIUYaming.TheMechanismofExtracellularSSTRegulatingSecretionofInsulin.JOURNALOFHUAZHONGNORMALUNIVERSITY(Nat.Sci.),2008;June,Vol.42,No.2,256-261.
9.HaoZhang,JieLuo,JunXiong,Xian-GuangLin,Zheng-XingWu,AnlianQu.Zf-and-Hsys-basedCmmeasurementunderthewhole-cellpatch-clamprecording.EurJPhysiol2009;457:1423–1434.
10.Ke-MingZhou,Yong-MingDong,QianGe,DanZhu,WeiZhou,Xian-GuangLin,TaoLiang,Zheng-XingWu,andTaoXu.PKAActivationBypassestheRequirementforUNC-31intheDockingofDenseCoreVesiclesfromC.elegansNeurons.Neuron.2007;November21,56,657–669.
11.JieLiu,QunfangWan,Xian-GuangLin,HongliangZhu,KirillVolynski,YuriUshkaryovandTaoXu.α-LatrotoxinModulatestheSecretoryMachineryviaReceptor-MediatedActivationofProteinKinaseC.Traffic2005;6:756–765.
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