个人简介
2018.10至今，暨南大学基础医学院生理学系，教授
2013.9-2018.9，暨南大学基础医学院生理学系，副教授
2011-2013，美国德克萨斯大学西南医学中心(UT Southwestern) ，分子遗传学系，博士后
博士后导师: Michael S. Brown 教授和Joseph L. Goldstein教授（1985年诺贝尔生理学或医学奖得主）
2006-2011，北京大学医学部，理学博士，（硕博连读）
2000-2005，安徽理工大学，医学学士
近期论文
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1.Hening Zhai#, Zhi Li#, Miao Peng#, Zhaoqi Huang, Tingfeng Qin, Linxi Chen, Hanbing Li, Heng Zhang, Weizhen Zhang*, Geyang Xu,* Takeda G Protein-Coupled Receptor 5-Mechanistic Target of Rapamycin Complex 1 Signaling Contributes to the Increment of Glucagon-Like Peptide-1 Production after Roux-en-Y Gastric Bypass. Ebiomedicine 2018 Jun;32:201-214.
2.Qinling Pan#,Tingfeng Qi#,Yuan Gao, Shaojian Li, Danjie Li, Miao Peng, Hening Zhai, Geyang Xu,* Hepatic mTOR-AKT2-Insig2 signaling pathway contributes to the improvement ofhepatic steatosis after Roux-en-Y Gastric Bypass in mice. BBA - Molecular Basis of Disease 2018 Dec 15;1865(3):525-534.
3.Danjie Li#, Shaojian Li#, Qinling Pan, Hening Zhai, Miao Peng, Xuanxuan Wang, Geyang Xu*, Gastric mammalian target of rapamycin signaling contributes to inhibition of ghrelin expression induced by Roux-en-Y Gastric Bypass. Cell Physiol Biochem 2018;51:664-680.
4.Qingjie Li#, Quan Yu#, Li Lin#, Heng Zhang, Miao Peng, Chunxia Jing, Geyang Xu*. Hypothalamic peroxisome proliferator-activated receptor gamma regulates ghrelin production and food intake. Neuropeptides. 2018;69:39-45.
5.Sushi Jiang, Hening zhai, Danjie Li, Jiana Huang, Heng Zhang, Ziru Li, Weizhen Zhang*, Geyang Xu*. AMPK-dependent Regulation of GLP-1 Expression in L Like Cells. J Mol Endocrinol 2016;57(3):151-160.
6.Xiaosi Hong, Heng Zhang, Hongbin Liang, Danjie Li, Jiana Huang, Sibo Jiang, Weizhen Zhang*, Geyang Xu*. Exendin-4 decreases ghrelin levels through mTOR signaling, Mol cell Endocrinol 2016; 437: 201-212.
7.Geyang Xu, Ziru Li, Li Ding, Hong Tang, Song Guo, Hongbin Liang, Huadong Wang, Weizhen Zhang*. Intestinal mTOR regulates GLP-1 production in L cells Diabetologia 2015;58(8):1887-97.
8.Geyang Xu*, Xiaosi Hong, Hong Tang, Sushi Jiang, Fenting Liu, Zhemin Shen, Ziru Li, Weizhen Zhang*. Ghrelin regulates GLP-1 production through mTOR signaling in L cells. Mol cell Endocrinol 2015, 416: 9-18.
9.Ziru li, Geyang Xu, Yan Qin, Chao Zhang, Hong Tang, Yue Yin, Xingxing Xiang, Yin Li, Jing Zhao, Michael Mulholland*, Weizhen Zhang*. Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway. Proc Natl Acad Sci U S A 2014;111(36):13163-8.
10.Geyang Xu, Zhigang Wang, Yin Li, Ziru Li, Hong Tang, Jing Zhao, Xinxin Xiang, Li Ding, Liangxiao Ma, Fang Yuan, Jian Fei, Wei Wang, Nanping Wang, Youfei Guan, Chaoshu Tang, Michael Mulholland, Weizhen Zhang. Ghrelin contributes to derangements of glucose metabolism induced by rapamycin in mice. Diabetologia 2012 Jun;55(6):1813-23.
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