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个人简介

李晓雯,女,山东德州人,讲师。2012年于中国海洋大学医药学院药物化学专业获医学博士学位。 主要从事生物无机化学和药物化学等方面的相关教学与科研工作。 围绕研究方向,在EuropeanJournalofMedicinalChemistry、JournalofPhotochemistryandPhotobiologyB:Biology等国际学术刊物上共发表SCI收录论文19篇,其中第一作者9篇,并列第一作者3篇。 电子信箱:lixiaowen5456@163.com

研究领域

研究内容主要包括:1.基于生物大分子相互作用的抗肿瘤药物的设计与合成研究;2.药物中间体的合成研究;3.海洋活性产物的结构修饰与优化。

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

主要论著(发表的主要论文): 1.Xiao-WenLi,Yong-JunZheng,Yan-TuanLi*,Zhi-YongWu,Cui-WeiYan.Synthesisandstructureofnewbicopper(II)complexesbridgedbyN-(2-aminopropyl)-N’-(2-oxidophenyl)oxamide:Theeffectsofterminalligandsonstructures,anticanceractivitiesandDNA-bindingproperties.Eur.J.Med.Chem.,46,3851–3857,2011 2.Xiao-WenLi,LinTao,Yan-TuanLi*,Zhi-YongWu,Cui-WeiYan.BimetalliccomplexesconstructedfromasymmetricalN,N’-bis(substituted)oxamide:Cytotoxicities,andreactivitiestowardsDNAandprotein.Eur.J.Med.Chem.,54,697–708,2012 3.Xiao-WenLi,Xue-JieLi,Yan-TuanLi*,Zhi-YongWu,Cui-WeiYan.SynthesesandstructuresofnewtrimetalliccomplexesbridgedbyN-(5-chloro-2-hydroxyphenyl)-N’-[3-(dimethylamino)propyl]oxamide:Cytotoxicactivities,andreactivitiestowardsDNAandprotein.J.Photoch.Photobio.B,118,22-32,2013 4.Xiao-WenLi,YuYu,Yan-TuanLi*,Zhi-YongWu,Cui-WeiYan.Synthesis,structure,cytotoxicactivitiesandDNA-bindingpropertiesoftetracopper(II)complexeswithdissymmetricalN,N’-bis(substituted)oxamidesasligands.Inorg.Chim.Acta,367,64–72,2011 5.Xiao-WenLi,XinLi,Yan-TuanLi*,Zhi-YongWu,Cui-WeiYan.Synthesisandstructuresofbinuclearcopper(II)complexesbridgedbyN-(5-chloro-2-hydroxyphenyl)-N’-[3-(dimethylamino)propyl]oxalamideligand:DNA-bindingpropertiesandcytotoxicactivities.J.Organ.Chem.,700,48–57,2012 6.Xiao-WenLi,Yan-TuanLi*,Zhi-YongWu,Cui-WeiYan.Synthesesandstructuresofbicopper(II)complexesbridgedbyN-(5-chloro-2-hydroxyphenyl)-N’-[3-(dimethylamino)propyl]oxamide:cytotoxicactivities,andreactivitiestowardsDNAandprotein.Inorg.Chim.Acta,390,190-198,2012

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