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中西医结合防治耳鼻咽喉疾病、肿瘤及其机制研究

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1. p53-inducible long non-coding RNA PICART1 mediates cancer cell proliferation and migration[J]. Int J Oncol,2017, 50(5):1671-1682. 2. A phosphomimetic mutant of RelA/p65 at Ser536 induces apoptosis and senescence: An implication for tumor-suppressive role of Ser536 phosphorylation. Int J Cancer,2016,138(5):1186-1198. 3. Overexpression of AKR1B10 in nasopharyngeal carcinoma as a potential biomarker[J]. Cancer Biomarkers, 2016, 16(1):127-135. 4. Cancer stem cell markers in nasopharyngeal carcinoma and its relevance for therapy [J]. Current Traditional Medicine,2016,2(2):115-123. 5. Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8 deficient mice[J]. Clin Cancer Res,2015,21(6):1466-1476. 6. AKR1B10 promotes breast cancer metastasis through integrin α5/δ-catenin mediated FAK/Src/Rac1 signaling pathway[J]. Oncotarget. 2016,7(28):43779-43791. 7. Apoptotic death of cancer stem cells for cancer therapy. Int J Mol Sci,2014,15(5):8335-8351. 8.Heat shock protein 90-alpha mediates AKR1B10 secretion through secretory lysosomes[J]. J. Biol. Chem,2013,288(51):36733-36740. 9. Enhancive effect of N,N'-dinitrosopiperazine on inducing precancerous lesion on nasal and nasopharyngeal epithelia of TgN(p53mt-LMP1)/HT mice [J]. J Zhejiang Univ Sci B,2009,10(3):172-179. 10. Downregulated NM23-H1 expression is associated with intracranial invasion of nasopharyngeal carcinoma[J]. British Journal of Cancer,2008,98:363 – 369.

学术兼职

国家自然科学基金、湖南省、浙江省自然科学基金网评专家;科技部、教育部、中国中西医结合学会、湖南省、吉林省科技奖励网评专家;湖南省食品药品监督管理局保健食品咨询专家(第一批);中国中医药研究促进会耳鼻咽喉科专业委员会常务理事,湖南省中西医结合学会第五届耳鼻咽喉专业委员会委员,湖南省医学会医学科普与健康教育专业委员会委员,中国生物化学与分子生物学会中医药生物化学与分子生物学分会理事,湖南省生物化学与分子生物学会理事,湖南省中医药学会中医基础理论专业委员会委员,湖南省病理生理学会第二届中西医结合专业委员会委员;《湖南中医药大学学报》常务编委;《中国中西医结合耳鼻咽喉科杂志》编委

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