熊亮 - 成都中医药大学

个人简介

博士毕业于清华大学北京协和医学院&中国医学科学院药物研究所。

研究领域

基于西南丰富的中药资源，关注活血类中药防治妇产科疾病和脑血管疾病领域，针对中医优势病种偏头痛、月经不调、痛经、产后复旧不良等，围绕益母草、川芎、姜黄、蓬莪术、红花等川产活血化瘀药材，开展系统的物质基础及创新药物发现研究。

近期论文

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Liang Xiong, Qin-Mei Zhou, Yike Zou, Ming-Hua Chen, Li Guo, Guan-Ying Hu, Zhao-Hua Liu, Cheng Peng*. Leonuketal, a spiroketal diterpenoid from Leonurus japonicus. Organic Letters, 2015, 17(24): 6238-6241. Qin-Mei Zhou#, Ming-Hua Chen#, Xiao-Hong Li, Cheng Peng*, Da-Sheng Lin, Xiao-Nian Li, Yang He, Liang Xiong*. Absolute Configurations and Bioactivities of Guaiane-Type Sesquiterpenoids Isolated from Pogostemon cablin. Journal of Natural Products, 2018, 81(9): 1919-1927. Fu Peng, Chun-Wang Meng, Qin-Mei Zhou, Jian-Ping Chen*, Liang Xiong*. Cytotoxic evaluation against breast cancer cells of isoliquiritigenin analogues from Spatholobus suberectus and their synthetic derivatives. Journal of Natural Products, 2016, 79(1): 248-251. Liang Xiong, Mei Zhu, Chenggeng Zhu, Sheng Lin, Yongchun Yang, Jiangong Shi*. Structure and bioassay of triterpenoids and steroids isolated from Sinocalamus affinis. Journal of Natural Products, 2012, 75(6): 1160-1166. Liang Xiong, Chenggeng Zhu*, Yanru Li, Ye Tian, Sheng Lin, Shaopeng Yuan, Jinfeng Hu, Qi Hou, Naihong Chen, Yongchun Yang, Jiangong Shi*. Lignans and neolignans from Sinocalamus affinis and their absolute configurations. Journal of Natural Products, 2011, 74(5): 1188-1200. Hai-Guo Su, Qin-Mei Zhou, Li Guo, Yuan-Jin Huang, Cheng Peng*, Liang Xiong*. Lanostane triterpenoids from Ganoderma luteomarginatum and their cytotoxicity against four human cancer cell lines. Phytochemistry, 2018, 156: 89-95. Juan Liu, Cheng Peng*, Qin-Mei Zhou, Li Guo, Zhao-Hua Liu, Liang Xiong*. Alkaloids and flavonoid glycosides from the aerial parts of Leonurus japonicus and their opposite effects on uterine smooth muscle. Phytochemistry, 2018, 145: 128-136. Ya-Cong He, Cheng Peng*, Xiao-Fang Xie, Ming-Hua Chen, Xiao-Nian Li, Meng-Ting Li, Qin-Mei Zhou, Li Guo, Liang Xiong*. Penchinones A–D, two pairs of cis-trans isomers with rearranged neolignane carbon skeletons from Penthorum chinense. RSC Advances, 2015, 5(94): 76788-76794. Yu-Lin He#, Jian-You Shi#, Cheng Peng*, Li-Jiao Hu, Juan Liu, Qin-Mei Zhou, Li Guo, Liang Xiong*. Angiogenic effect of motherwort (Leonurus japonicus) alkaloids and toxicity of motherwort essential oil on zebrafish embryos. Fitoterapia, 2018, 128: 36-42. Huan Zhu#, Qin-Mei Zhou#, Cheng Peng*, Ming-Hua Chen, Xiao-Nian Li, Da-Sheng Lin, Liang Xiong*. Pocahemiketals A and B, two new hemiketals with unprecedented sesquiterpenoid skeletons from Pogostemon cablin. Fitoterapia, 2017, 120: 67-71. Chun-Wang Meng, Yu-Lin He, Cheng Peng*, Xing-Jie Ding, Li Guo, Liang Xiong*. Picrotoxane sesquiterpenoids from the stems of Dendrobium nobile and their absolute configurations and angiogenesis effect. Fitoterapia, 2017, 121: 206-211. Liang Xiong, Qin-Mei Zhou, Cheng Peng*, Xiao-Fang Xie, Lu-Si Liu, Li Guo, Ya-Cong He, Lian Yang, Zhao-Hua Liu. Bis-spirolabdane diterpenoids from Leonurus japonicus and their anti-platelet aggregative activity. Fitoterapia, 2015, 100: 1-6. Ya-Cong He, Yike Zou, Cheng Peng*, Jian-Lin Liu, Cheng-Jun He, Li Guo, Xiao-Fang Xie, Liang Xiong*. Penthorin A and B, two unusual 2,4′-epoxy-8,5′-neolignans from Penthorum chinese. Fitoterapia, 2015, 100: 7-10. Juan Liu, Cheng Peng*, Cheng-Jun He, Jian-Lin Liu, Ya-Cong He, Li Guo, Qin-Mei Zhou, Huai Yang, Liang Xiong*. New amino butenolides from the bulbs of Fritillaria unibracteata. Fitoterapia, 2014, 98: 53-58. Fu Peng, Liang Xiong*, Xiao-Mei Zhao. A Bicyclic Diterpenoid with a New 15,16-Dinorlabdane Carbon Skeleton from Leonurus japonicus and Its Coagulant Bioactivity. Molecules, 2013, 18(11): 13904-13909. Liang Xiong, Cheng Peng*, Qin-Mei Zhou, Feng Wan, Xiao-Fang Xie, Li Guo, Xiao-Hong Li, Cheng-Jun He, Ou Dai. Chemical composition and antibacterial activity of essential oils from different parts of Leonurus japonicus Houtt. Molecules, 2013, 18(1): 963-973. Liang Xiong, Qin-Mei Zhou, Cheng Peng*, Xiao-Fang Xie, Li Guo, Xiao-Hong Li, Juan Liu, Zhao-Hua Liu, Ou Dai*. Sesquiterpenoids from the herb of Leonurus japonicus. Molecules, 2013, 18(5): 5051-5058. Liang Xiong, Zhi-Xing Cao, Cheng Peng*, Xiao-Hong Li, Xiao-Fang Xie, Ting-Mo Zhang, Qin-Mei Zhou, Lian Yang, Li Guo*. Phenolic glucosides from Dendrobium aurantiacum var. denneanum and their bioactivities. Molecules, 2013, 18(6): 6153-6160. Liang Xiong, Cheng Peng*, Xiao-Fang Xie, Li Guo, Cheng-Jun He, Zhao Geng, Feng Wan, Ou Dai, Qin-Mei Zhou. Alkaloids isolated from the lateral root of Aconitum carmichaelii. Molecules, 2012, 17(8): 9939-9946. Xiao Zhang, Li-Hua Zou, Yu-Lin He, Cheng Peng, Li Guo*, Liang Xiong*. Triterpenoid saponins from the buds of Lonicera similis. Natural Product Research, 2017, doi.org/10.1080/14786419.2017.1408092.