刘举 - 辽宁大学

个人简介

刘举，男，硕士学位，博士在读、副研究员(医药学)、硕士生导师。2003年毕业于鞍山师范学院，获应用化学学士学位，2006年毕业于辽宁大学，获有机化学硕士学位。2006年至今于辽宁大学从事药学研究及科研工作。目前沈阳药科大学药物化学专业博士在读。主要从事药物化学的相关教学及科研工作，研究方向主要为基于靶点的新药设计开发，天然产物结构修饰及药物制备工艺优化。承担国家“十一五、十二五”规划“重大新药创制”专项2项、辽宁大学青年科学基金项目1项、辽宁省及沈阳市科技项目9项等10余项科研课题，在国内外期刊发表论文40余篇，提交7项专利申请。获得辽宁省自然科学成果奖一等奖1项

研究领域

新型抗肿瘤和抗菌药物的设计，天然产物结构修饰，药物制备工艺优化

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.Ju Liu, Minhua Nie, Yanjing Wang, et al. Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing 1,2,4-triazolone moiety as c-Met kinase inhibitors [J].European Journal of Medicinal Chemistry,2016, 123: 431-446. (SCI) 2.Ju Liu, Xin-Wei Zhang, Duan-Zheng Song, et al. Synthesis of several new 1-arylpyrazolo[3,4-d]pyrimidines containing amide moiety[J].Journal of Chemical Research, 2016, 40: 92-94. (SCI) 3.Ju Liu, Duan-Zheng Song, Yan-Qiu Tian, et al. Synthesis, Crystal Structure, and Biological Activity of 5-(4-fluorophenyl)-N,N-dimethyl -7-(trifluoromethyl)pyrazolo [1,5-a]pyrimidine-3-carboxamide[J].Journal of Chemical Research, 2016, 40: 107-109. (SCI) 4.Ju Liu, Xin-wei Zhang, Yang Wang, et al. A new efficient synthesis of 4- alkoxy-1,6-diaryl-1H-pyrazolo[3,4-d] pyrimidine derivatives,Synthetic Communications, 2015, 45(8): 1009-1017. (SCI) 5.Liu Ju, Ge Hong-Guang，Lu Jiu-Fu. Synthesis, crystal structure, and biological activity of diethyl-2-[5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamido]pentanedioate[J].Journal of Chemical Research.2015, 39: 768-770. 6. Zhi-Qiang Cai,Ju Liu*, Ming-Xiang Shao, et al. A Cup-like Structure: Synthesis, Crystal Structure and Anti-Cancer Activity of 2-(2-(4,5-diphenyl-1H-imidazol-1-yl)acetamido)ethyl adamantane-1-carboxylate[J].J.Chem.Soc.Pak.2014, 36(4): 717-722. 7.Ju Liu, Xinwei Zhang, Dan Wang. Advances on small-molecule aurora kinase inhibitors [J].Chinese Journal of Medicinal Chemistry, 2016, 26(3): 225-235. 8. Meirong Zhang, Ju Liu*, , Xinwei Zhang, et al.Ｒesearch Progress of Synthesis and Pharmacological Activity of Pyrazolo［3,4-d］Pyrimidine Derivatives [J]. Chinese Journal of Medicinal Chemistry, 2015, 50(3): 194-200. 9. Meirong Zhang, Ju Liu*, Yang Wang. Research progress of mitogen-activated protein kinase and related drugs [J].Chinese Journal of Medicinal Chemistry, 2014, 24(3): 231-240. 10.Ju Liu, Jing Chunyan, Wang Yang, et al. Synthesis of 3, 6-Diarylpyrazolo［1, 5-a］pyrimidines [J].Chinese Journal of Applied Chemistry,2013, 30(12): 1494-1497.