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S. Zeng, C. Chen, L. Zhang, X. Liu, M. Qian, H. Cui, J. Wang*, Q. Chen*, X. Peng. Activation of pyroptosis by organelle-targeting photodynamic therapy to amplify immunogenic cell death for anti-tumor cancer immunotherapy. Bioactive Materials, 2022. (IF: 16.874)
Q. Chen, K. Osada*, T. Ishii, M. Oba, S. Uchida, T. A. Tockary, T. Endo, Z. Ge, H. Kinoh, M. R. Kano, K. Itaka, K. Kataoka*. Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors. Biomaterials, 33, 18, 4722, 2012. (IF: 15.304)
Q. Chen, K. Osada*, Z. Ge, S. Uchida, T. A. Tockary, A. Dirisala, A. Kim, K. Toh, K. M. Takeda, Y. Li, T. Ishii, M. Oba, Y. Matsumoto, K. Itaka, K. Kataoka*. Polyplex micelles installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting. Biomaterials, 113, 253, 2016. (IF: 15.304)
Z. Ge#, Q. Chen#, K. Osada*, X. Liu, T. A. Tockary, S. Uchida, A. Dirisala, T. Ishii, T. Nomoto, K. Toh, Y. Matsumoto, M. Oba, M. R. Kano, K. Itaka, K. Kataoka*. Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors. Biomaterials, 35, 10, 3416, 2014. (IF: 15.304)
Q. Chen#,*, R. Qi#, X. Chen, X. Yang, S. Wu, H. Xiao, W. Dong*. A targeted and stable polymeric nanoformulation enhances systemic delivery of mRNA to tumors. Molecular Therapy, 25(1), 92, 2017. (IF: 12.910)
H. Cui, Y. Wang, L. Chen, M. Qian, L. Zhang, X. Zheng, X. Yang, L. Chen, Y. Zhao*, Q. Chen*, J. Wang*. Chemotherapeutic potency drastically stimulated by SNAI1-knockdown based on multifaceted nanomedicine. Journal of Controlled Release, 337, 343-355, 2021. (IF: 11.407)
J. Xia, M. Qian, Q. Yao, Z. Meng, H. Cui, L. Zhang, Y. Li, S. Wu, J. Wang*, Q. Chen*, X. Peng. Synthetic infrared photosensitizer with multi-level targeting functions for precision photodynamic therapy. Journal of Controlled Release, 334, 263-274, 2021. (IF: 11.407)
J. Li#, Q. Chen#, Z. Zha, K. Toh, A. Dirisala, Y. Matsumoto, K. Osada, K. Kataoka*, Z. Ge*. Ternary polyplex micelle with PEG shells and intermediate barrier to complexed DNA cores for efficient gene delivery. Journal of Controlled Release, 209, 77, 2015. (IF: 11.407)
Y. Wang, X. Zheng, J. Liu, Q. Chen*, Y. Zhao*. Convergent arrangement of sgRNA and Cas9 into CRISPRsome for transcellular trafficking. ACS Materials Letters, 4, 505-510, 2022. (IF: 11.170)
T. Hao#, Q. Chen#, Y. Qi, P. Sun, D. Chen, W. Jiang, K. Liu, H. Sun, L. Li, J. Ding*, Z. Li*. Biomineralized Gd2O3@HSA nanoparticles as a versatile platform for dual-modal imaging and chemo-phototherapy-synergized tumor ablation. Advanced Healthcare Materials, 8, 1901005-1901015, 2019. (IF: 11.092)
S. Chen#, Q. Chen#, Q. Li, J. An, P. Sun, J. Ma, H. Gao*. Biodegradable synthetic antimicrobial with aggregation induced emissive luminogens for temporal antibacterial activity and facile bacteria detection. Chemistry of Materials, 30, 1782, 2018. (IF: 10.508)
L. Zhang, M. Qian, H. Cui, J. Xia, S. Zeng, J. Wang*, Qixian Chen*. Spatiotemporal concurrent liberation of cytotoxins from dual-prodrug nanomedicine to intracellular gradients for synergistic anti-tumor therapy. ACS Applied Materials & Interfaces, 13(5), 6053-6068, 2021. (IF: 10.383)
Q. Chen#,*, R. Qi#, X. Chen, H. Xiao, W. Dong*. Polymeric nanostructure compiled with multifunctional components to exert tumor-targeted delivery of anti-angiogenic gene for tumor growth suppression. ACS Applied Materials & Interfaces, 8, 24404, 2016. (IF: 10.383)
X. Han#, Q. Chen#, H. Lu, J. Ma, H. Gao*. Probe intracellular trafficking of polymeric DNA delivery vehicle by functionalization with aggregation-induced emissive tetraphenylethene derivative. ACS Applied Materials & Interfaces, 7, 28494, 2015. (IF: 10.383)
X. Chen*, H. Gu, J. Yang, S. Wu, J. Liu, X. Yang, Q. Chen*. Controlled PEGylation crowdedness for polymeric micelles to pursue ligand-specified privileges as nucleic acid delivery vehicles. ACS Applied Materials & Interfaces, 9, 8455-8459, 2017. (IF: 10.383)
D. Liu, X. Han, H. Lu, D. Ma, Q. Chen*, H. Gao*. Aggregation-induced-emissive molecule incorporated into polymeric nanoparticulate as FRET donor for observing doxorubicin delivery. ACS Applied Materials & Interfaces, 7, 23760, 2015. (IF: 10.383)
X. Yang, Q. Chen*, J. Yang, S. Wu, J. Liu, Z. Li, D. Liu, X. Chen, Y. Qiu*.Tumor-targeted accumulation of ligand-installed polymeric micelles depends on PEGylation crowdedness. ACS Applied Materials & Interfaces, 9(50), 44045-44052, 2017. (IF: 10.383)
H. Cui, L, Zhang, S. Zeng, Y. Wang, Z. Li, J. Wang*, Q. Chen*. Charge reversible pro-ribonuclease enveloped in virus-like synthetic nanocapsules for systemic treatment of intractable glioma. ACS Applied Materials & Interfaces, 14(27), 30493-30506, 2022. (IF: 10.383)
W. Wang#, S. Wu#, J Wang, Z. Li, H. Cui, S. Lin, J. Zhu, Q. Chen*. Superoxide dismutase transcellular shuttle constructed from dendritic MOF and charge reversible protein derivatives. Chemical Science, 10, 4476, 2019. (IF: 9.969)
J. Xia, J. Li, Q. Yao, M. Qian, H. Cui, L. Zhang, L. Guo, Y. Li, Q. Chen*, J. Wang*, X. Peng. Mitochondria specific oxidative injury by near-infrared energy transfer nanoclusters for amplified photodynamic potency. Journal of Colloid and Interface Science, 557, 45-54, 2019. (IF: 9.965)
J. Wang, Y. Xia, H. Liu, J. Xia, M. Qian, L. Zhang, L. Chen, Q. Chen*. Poly(lactobionamidoethyl methacrylate)-based copolymer with ultrasound-labile motif in manufacture of drug delivery nanoparticulates for augmented efficacy to hepatocellular carcinoma. Journal of Colloid and Interface Science, 551, 1-9, 2019.(IF: 9.965)
Y. Wang, X. Zheng, J. Liu, Q. Chen*, Y. Zhao*. Virus-like siRNA construct dynamically responsive to sequential microenvironments for potent RNAi. Journal of Colloid and Interface Science, 622, 938-949, 2022. (IF: 9.965)
J. Wang, X. Shi, Q. Bo, H. Wang, F. Wei, J. Liu, L. Zhang, Q. Chen*, X. Sun*. Synthetic anti-angiogenic genomic therapeutics for treatment of neovascular age-related macular degeneration. Asian Journal of Pharmaceutical Science, 16, 623-632, 2021. (IF: 9.273)
J. Wang, H. Wang, P. Sun, H. Cui, X. Yang, Q. Chen*. Circumvent PEGylation dilemma by implementing matrix metalloproteinase-responsive chemistry for promoted tumor gene therapy. Chinese Chemical Letters, 2021. (IF: 8.455)
H. Fu, Y. Huang, H. Lu, J. An, D. Liu, Y. Zhang, Q. Chen*, H. Gao*. A theranostic saponin nano-assembly based on FRET of an aggregation induced emission photosensitizer and photon up-conversion nanoparticles. Journal of Materials Chemistry B, 7, 5286-5290, 2019. (IF: 7.571)
J. Li, Y. Han, Q. Chen*, H. Shi, S. Rehman, M. Siddiq, Y. Liu, Z. Ge*, S. Liu. Dual endogenous stimuli-responsive polyplex micelles as smart two-step delivery nanocarriers for deep tumor tissue penetration and combating drug resistance of cisplatin. Journal of Materials Chemistry B, 2, 13, 1813, 2014. (IF: 7.571)
H. Zhu, J. An, C. Pang, S. Chen, W. Li, J. Liu, Q. Chen*, H. Gao*. A multifunctional polymeric gene delivery system for circumvent biological barriers. Journal of Materials Chemistry B, 7, 384-392, 2019. (IF: 7.571)
Y. Huang#, Q. Chen#, H. Lu, J. An, H. Zhu, X. Yan, W. Li, H. Gao*. Near-infrared AIEgen-functionalized and diselenide-linked oligo-ethylenimine with self-sufficing ROS to exert spatiotemporal responsibility for promoted gene delivery. Journal of Materials Chemistry B, 6, 6660-6666, 2018. (IF: 7.571)
Y. Li, J. Li, B. Chen, Q. Chen*, G. Zhang, Z. Ge*, S. Liu. Polyplex micelles with thermo-responsive heterogeneous coronas for prolonged blood retention and promoted gene transfection. Biomacromolecules, 15, 8, 2914, 2014. (IF: 6.978)
X. Han#, Q. Chen#, W. Lu, G. Wu, J. Ma, H. Gao*. Incorporation of aggregation-induced-emissive tetraphenylethene derivative into cationic gene delivery vehicles manifested nucleus translocation of DNA as uncomplexed form. Chemical Communications, 52, 3907, 2016. (IF: 6.065)
P. Sun, Z. Li, J. Wang, H. Gao, X. Yang, S. Wu, D. Liu, Q. Chen*. Transcellular delivery of messenger RNA payloads by cationic supramolecular MOF platform. Chemical Communications, 54, 11304-11307, 2018. (IF: 6.065)
D. Liu#, Q. Chen#, Y. Long, J. Ma, H. Gao*. A thermo-responsive polyurethane organogel for norfloxacin delivery. Polymer Chemistry, 9, 228, 2018. (IF: 5.364)
S. Chen#, Q. Chen#, S. Dong, J. Ma, Y. Yang, L. Chen*, H. Gao*. Polymerbrush decorated MOF nanoparticles loaded with AIEgens, anticancer drug, and supramolecular glue for regulating and in situ observing DOX release. Macromolecular Bioscience, 18(12), 1800317, 2018. (IF: 5.859)
T. Wang#, Q. Chen#, W. Li, G. Wu, J. Ma, H. Gao*. Shedding PEG palisade by temporal photo-stimulation and intracellular reducing milieu for facilitated intracellular trafficking and DNA releasing. Bioconjugate Chemistry, 27, 1949, 2016. (IF: 6.069)
J. Xia, J. Wang, X. Wang, M. Qian, L. Zhang, Q. Chen*.Ultrasound-responsive nanoparticulate for selective amplification of chemotherapeutic potency for ablation of solid tumors. Bioconjugate Chemistry, 29(10), 3467-3475, 2018. (IF: 6.069)
Q. Bai, J. Liu, J. Tang, Z. Li, X. Zheng, Q. Chen*. Redox-responsive polymeric RNAi based on multivalent conjugation of siRNA for improved intracellular delivery. Bioconjugate Chemistry, 30, 11, 2777-2781, 2019. (IF: 6.069)
X. Xie, J. Wang, L. Zhang, S. Zeng, X. Su, Q. Chen*. Bioresorbable depot for sustained release of immunostimulotory resiquimod in suppressing both primary triple-negative breast tumors and metastatic occurrence. Bioconjugate Chemistry, 32(5), 1008-10016, 2021. (IF: 6.069)
Z. Jiang, Q. Chen*, X. Yang, X. Chen, Z. Li, D. Liu, W. Li, Y. Lei, H. Gao*. Polyplex micelle with pH-responsive PEG detachment and functional tetraphenylene incorporation to promote systemic gene expression. Bioconjugate Chemistry, 28 (11), 2849-2858, 2017. (IF: 6.069)
C. Zhang, M. Qian, L. Zhang, H. Zheng, M Zhang, Y. Jiao, Y. Kafuti, Q. Chen*, J. Wang*. A near-infrared fluorescent probe with ultra-large Stokes shift for the detection of HNO in cells and mice. Journal of Luminescence, 241, 2021. (IF: 4.171)
J. Yang*, X. Wang, R. Liang, R. Kong, Y. Sun, J. Tang, L. Li, L. Xue, Q. Chen*. Polymorphism, thermal stability and biodegradation of poly(1,4-butylene adipate) manipulated by a benzene-1,3,5-tricarboxamide-based nucleating agent. Journal of Materials Science, 53, 10569-10581, 2018. (IF: 4.682)
L. Zhang, M. Qian, J. Wang*, J. Xia, H. Cui, Q. Chen*. Nitrophenyl-engaged photocleavage of an amphiphilic copolymer for spatiotemporally controlled drug release. Journal of Materials Science, 54(20), 13298-13313, 2019. (IF: 4.682)
J. Yang, R. Liang, Y. Chen*, C. Zhang, R. Zhang, X. Wang, R. Kang, Q. Chen*. Using a self-assemblable nucleating agent to tailor crystallization behavior, crystal morphology, polymorphic crystalline structure, and biodegradability of poly(1,4-butylene adipate). Industrial & Engineering Chemistry Research, 56(28), 7910-7919, 2017. (IF: 4.326)
Q. Chen, K. Osada*, P. Matthew, S. Uchida, T. A. Tockary, A. Dirisala, K. M. Takeda, S. Oniyanagi, K. Itaka, K. Kataoka*. A tadpole-shaped gene carrier with distinct phase segregation in ternary polymeric micelle. Soft Matter, 11, 14, 2718, 2015. (IF: 4.046)
H. Cui, J. Xia, L. Zhang, M. Qian, H. Wang, J. Wang*, Q. Chen*. Integument of cytoplasmic membrane onto cationic DNA condensates for selective gene expression at homologous cells. ACS Applied Bio Materials, 2, 4537-4544, 2019.
L. Zhang, Q. Chen*, J. Wang*. Advances in reactive oxygen species responsive antineoplastic prodrugs. Acta Chimica Sinica, 78(7), 642-656, 2020. (IF: 2.789)
Y. Wang#, X. Zheng#, J. Liu, Q. Chen*, Y. Zhao*. Tumor-targeted anti-VEGF RNAi capable of sequentially responding to intracellular microenvironments for potent systemic tumor suppression. ACS Applied Bio Materials, 3(12), 9145-9155, 2020.
Q. Chen, X. Sui, L. Zhang, Q. Zhang, X. Han, X. Su, H. Cui, M. Qian, S. Zeng, J. Wang*. Camptothecin nanoprodrug possessing dual-responsiveness to endolysosomal pH and cytosolic redox for amplified cytotoxic potency. ACS Applied Bio Materials, 4(6), 4990-4998, 2021.
Y. Wang, S. Zeng, C. Cui, H. Li, J. Wang, Q. Chen. Reversible chemical protein modification to endogenous glutathione and its utilities in the manufacture of transcellular pro-enzymes. Biomacromolecules, 23(5), 2138-2149, 2022. (IF: 6.978)
M. Zhang, J. Liu, Y. Jiao, L. Zhang, H. Cui, S. Zeng, H. Li, C. Zhang, J. Lin, X. Wang*, J. Wang*, Q. Chen*. Revascularization by virus-like self-spooling toroidal plasmid condensates for angiogenesis of hindlimb ischemia. ACS Applied Materials & Interfaces, 2022. (IF: 10.383)
Y. S. Kafuti, S. Zeng, M. Qian, C. Zhang, X. Liu, J. Wang*, Q. Chen*. A novel NIR fluorescent probe with fast response and large stokes shift for the detection and imaging of hypochlorous acid in living cells. Dyes and Pigments, 199, 110067, 2022. (IF: 5.122)
Q. Lu, H. Cui, W. Li, T. Liu*, Q. Chen*, Q. Yang*. Synthetic nanoscale RNAi constructs as pesticides for the control of Locust Migratoria. Journal of Agricultural and Food Chemistry, 2022. (IF: 5.895)
H. Cui, M. Zhang, L. Zhang, H. Li, Y. Zhao, J. Wang*, Qixian Chen*. pH-responsive organic/inorganic hybrid nanocolloids for transcellular delivery of ribonucleolytic payloads toward targeted anti-glioma therapy. Journal of Colloid and Interface Science, 2022. (IF: 9.965)
L. Zhang, H. Cui, H. Zheng, X. Yin, J. Lin, Y. Wang, Y. Zhao, H. Li, J. Wang, Q. Chen*. Simultaneous knockdown of immune suppressive CD47 and PD-L1 by tumor microenvironment-responsive multifaceted prodrug nanomedicine for amplified anti-tumor potencies. Journal of Controlled Release, 2022. (IF: 11.407)
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