吴练秋 - 中国医学科学院药物研究所 -

个人简介

教育背景 1. 天津医科大学临床医学系本科毕业，获医学学士学位。 2. 中国协和医科大学病理学和病理生理学系硕士研究生毕业，获硕士学位。 3. 北京协和医学院免疫学系博士研究生毕业，获博士学位。工作经历 1. 1997年至2007年，任职于武警部队后勤学院临床医学系病理学与病理生理学教研室。 2. 2010年至今，任职于中国医学科学院药物研究所药理室。

研究领域

专业研究领域为抗炎免疫药物药理学，包括免疫和炎症相关疾病的新药研发和作用机制研究。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. HaiJing Zhang, AnJun Deng, ZhiHui Zhang, ZiHan Yu, Yang Liu, ShanYing Peng, LianQiu Wu*, HaiLin Qin, WenJie Wang*. The Protective Effect of Epicatechin on Experimental Ulcerative Colitis in Mice Is Mediated by Increasing Antioxidation and by the Inhibition of NF-κB pathway. Pharmacological Reports, 2016. (online) 2. Haijing Zhang, Lianqiu Wu, Yang Liu, Shanying Peng, Wenjie Wang*. The antinociceptive effect and mechanism of action of SY0916. International Immunopharmacology, 2016. (online) 3. Zhang ZH, Zhang HJ, Deng A, Wang B, Li ZH, Liu Y, Wu LQ*, Wang WJ, Qin HL*.Synthesis and Structure-activity Relationships of Quaternary Coptisine Derivatives as Potential Anti-ulcerative Colitis Agents. J Med Chem. 2015; 58(18):7557-71 4. Hai-Jing Zhang, Wen-Yang Han, Shan-Ying Peng, Yang Liu, Lian-Qiu Wu*, & Wen-Jie Wang*. The inhibition effect and mechanism study of SY0916 on pulmonary fibrosis. Journal of Asian Natural Products Research. 2014; 16(6): 658–666 5. Wu LQ *, Zhang XM, Tang SQ, Che YC, Zhang Y, Liu LD, Li QH. A cellular response protein identified in HSV1 infection is capable of inhibitIng viral replication via interaction with ATF5. SCIENCE CHINA LIFE SCIENCES.2013; 56 (12): 1127–1133 6. Wu LQ*, OU Y, Liu Y, Wang L, Peng SHY, Wang WJ . Inhibitory effects of SY0916, a platelet activating factor receptor antagonist, on the angiogenesis of Human Umbilical Vascular endothelial cells. Journal of Asian Natural Products Research. 2011; 13(11):984-992 7. Zhi Hui Zhang, Lian Qiu Wu, An Jun Deng, Jin Qian Yu, Zhi Hong Li, Hai Jing Zhang, Wen Jie Wang, Hai Lin Qin*. New Synthetic Method of 8-Oxocoptisine Starting from Natural Quaternary Coptisine as anti-Ulcerative Colitis Agent. Journal of Asian Natural Products Research. 2014; 16(8) :841-846 8. Zhi-Hui Zhang, An-Jun Deng, Lian-Qiu Wu, Lian-Hua Fang, Jin-Qian Yu, Zhi-Hong Li, Tian-Yi Yuan, Wen-Jie Wang, Guan-Hua Du, Hai-Lin Qin*. Syntheses and structure–activity relationships in cytotoxicities of 13-substituted quaternary coptisine derivatives. Eur. J. Med. Chem. 2014;86:542-549 9. JQ Yu, AnJ Deng, LQ Wu, ZH Zhang, Y Liu, WJ Wang, HL Qin*. Osteoclast-inhibiting Saikosaponin Derivertives from Bupleurum Chinense. Fitoterapia. 2013; 85: 101-108 10. Jin Ren, Yan-Gai Wang, Ai-Guo Wang, Lian-Qiu Wu, Hai-Jing Zhang, Wen-Jie Wang, Ya-Lun Su, Hai-Lin Qin*. Cembranoids from the Gum Resin of oswellia carterii as Potential Antiulcerative Colitis Agents. J Nat Prod. 2015;78:2322−2331 11. Jian Zhou , Chuang-Jun Li , Jing-Zhi Yang , Jie Ma, Lian-Qiu Wu, Wen-Jie Wang , Dong-Ming Zhang. Phenylpropanoid and lignan glycosides from the aerial parts of Lespedeza cuneata. Phytochemistry. 2016;121:58-64 12. Guo L, Wu WJ, Liu LD, Wang LC, ZhangY, Wu LQ , GuanY, Li QH*. Herpes Simplex Virus 1 ICP22 Inhibits the Transcription of Viral Gene Promoters by Binding to and Blocking the Recruitment of P-TEFb. PLOS ONE. 2012; 7 (9):e45749 13. 吴练秋，欧阳雪宇，刘洋，彭珊瑛，王霖，王文杰*。血小板激活因子受体拮抗剂SY0916抑制巨噬细胞血管生成作用的研究。中国药学杂志。2011；46(12)：46-52 14. 邓安珺，张海婧，张志辉，李志宏，马林，吴丰，吴练秋，王文杰，秦海林*。巨峰葡萄籽抗氧化活性成分研究。中国中药杂志。2015，40（21）：19-22 15. 刘洋，邓安郡，马林，张海婧，张志辉，吴练秋，申竹芳，王文杰*，秦海林*。小果博落回的化学成分及苯菲啶生物碱的xbp1转录激活作用评价。药学学报。2015;50（2）:207-210