林建平 - 中国科学院天津工业生物技术研究所 -

个人简介

1、学习经历： 2001/8–2005/07，美国杜克大学，化学系，博士 2000/8–2001/7，美国匹兹堡大学，化学院，博士研究生 1997/09–2000/07，北京大学，化学院，硕士 1992/09–1997/07，北京大学，化学院，本科 2、工作经历： 2009/12–至今，南开大学，药学院，教授 2006/03–2009/11，美国希望之城医学中心，贝克曼研究所，博士后 2005/08–2006/02，美国杜克大学，化学系，博士后 2、专著： [1]James C.Sung;Jianping Lin,Diamond Nanotechnology:Synthesis and applications.Pan Stanford Publishing,2009. [2]Spiros S.Skourtis;Jianping Lin;David N.Beratan,The Effects of Bridge Motion on Electron Transfer Reactions Mediated by Tunneling,Chapter 18 in Modern Methods for Theoretical Physical Chemistry of Biopolymers.Edited By E.B.Starikov;S.Tanaka;J.P.Lewis,Elsevier Press,June 2006.

研究领域

计算生物学 1.酶的全新设计 2.与酶相关数据库建设、挖掘及模型建立 3.酶反应机制理论模拟 4.与电能细胞相关蛋白设计

近期论文

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[1]Jianping Lin*;Pi Liu;Hua-ZhengYang;Nagarajan Vaidehi*,Factors That Affect the Computational Prediction of Hot Spots in Protein-Protein Complexes,Comput.Mol.Biosci.,2,pp23-34,2012. [2]Ralf Buettner;Renzo Corzano;Rumana Rashid;Jianping Lin;Maheswari Senthil;Michael Hedvat;Anne Schrodinger;Allen Mao;Andreas Herrmann;John Kim;Hongzhi Li;Yate-Ching Yuan;Kenichi Yakushijin;Fumiko Yakushijin;Nagarajan Vaidehi;Roger Moore;Gabriel Gugiu;Terr D Lee;Richard Yip;Yuan Chen;Richard Jove*;David Horne*;John C Williams*,Alkylation of cycteine 468 in Stat3 defines a novel site for therapeutic development,ACS Chem.Biol.,6(5),pp432-443,2011. [3]Jianping Lin;Ralf Buettner;Yate-Ching Yuan;Richard Yip;David Horne;Richard Jove;Nagerajan Vaidehi*,Molecular dynamics simulations of the conformational changes in Signal Transducers and Activators of Transcription,Stat1 and Stat3,J.Mole.Graphics Model.,28(4),pp347-356,2009. [4]Jianping Lin;Nadrian C.Seeman;Nagarajan Vaidehi*,Molecular dynamics simulations of insertion of chemically modified DNA nanostructures into water-chloroform interface,Biophys.J.,95(3),pp1099-1107,2008. [5]Jianping Lin;Ilya A.Balabin;David N.Beratan*,The Nature of Aqueous Tunneling Pathways between Electron-transfer Proteins,Science,310(5752),pp1311-1313,2005.related news:“Water can ease electron transfer between proteins”Chemical&Engineering News November 28,2005.Page 11. [6]Jianping Lin;David N.Beratan*,Simulation of Electron transfer between Cytochrome c2 and the Bacterial Photosynthetic Reaction Center:Brownian Dynamics Analysis of the Native Proteins and Double Mutants,J.Phys.Chem.B,109(15),7529-7534,2005. [7]Jianping Lin;David N.Beratan*,Tunneling while Pulling:The Dependence of Tunneling Current on End-to-End Distance in a Flexible Molecule,J.Phys.Chem.A,108(5752),5655-5661,2004.