程震 - 中国科学院上海药物研究所 -

个人简介

教育经历 1990.9-1994.7 四川大学化学系化学学士 1994.9-1997.7 中国原子能科学研究院同位素所同位素技术硕士 1997.9-2001.7 美国密苏里大学化学系哲学博士 2001.9-2003.8 美国哈佛大学医学院放射系博士后工作经历 2021.03-至今中国科学院上海药物所分子影像中心，研究员、主任 2014.06-2021-02 斯坦福大学医学院放射科，副教授 2007.09-2014.05 斯坦福大学医学院放射科，助理教授 2003.09-2007.08 斯坦福大学医学院放射科，研究科学家

研究领域

1. 分子影像及多模态分子探针的研究 2. 放射性药物研究 3. 纳米医学

近期论文

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Chang B, Li D, Ren Y, Qu C, Shi X, Liu R, Liu H, Tian J, Hu Z*, Sun T*, Cheng Z*. A phosphorescent probe for in vivo imaging in the second near-infrared window. Nature Biomedical Engineering. 2021. doi: 10.1038/s41551-021-00773-2. Chen H, Shou K, Chen S, Qu C, Wang Z, Jiang L, Zhu M, Ding B, Qian K, Ji A, Lou H, Tong L, Hsu A, Wang Y, Felsher DW, Hu Z*, Tian J*, Cheng Z*. Smart Self-Assembly Amphiphilic Cyclopeptide-Dye for Near-Infrared Window-II Imaging. Advanced Materials. 2021; Mar 12:e2006902. doi: 10.1002/adma.202006902. Yang J, He S, Hu Z*, Zeyu Zhang, Caiguang Cao, Cheng Z*, Fang C*, Tian J*. In vivo multifunctional fluorescence imaging using liposome-coated lanthanide nanoparticles in near-infrared-II/IIa/IIb windows. Nano Today. 2021, 38: 101120. https://doi.org/10.1016/j.nantod.2021.101120. Hu Z, Fang C, Li B, Zhang Z, Cao C, Cai M, Su S, Sun X, Shi X, Li C, Zhou T, Zhang Y, Chi C, He P, Xia X, Chen Y, Gambhir SS*, Cheng Z*, Tian J*. First-in-human liver-tumour surgery guided by multispectral fluorescence imaging in the visible and near-infrared-I/II windows. Nature Biomedical Engineering. 2020, 4, 259-271. Liang J#, Wang H#, Ding W, Huang J, Zhou X, Wang H, Dong X, Li G, Chen E, Zhou F, Fan H, Xia J, Shen B, Cai D, Lan P, Jiang H, Ling J, Cheng Z*, Liu X*, Sun J*. Nanoparticle-Enhanced Chemo-immunotherapy to Trigger Robust Antitumor Immunity. Science Advances, 2020; 6(35): eabc3646. Li D, Qu C, Wu Y, Hu X, Liu Q, Qian K, Chang B, Zhang X, Yuan Y, He S, Ko T, Yu A*, Cheng Z*. Monitoring the real-time circulatory system-related physiological and pathological processes in vivo using a multifunctional NIR-II probe. Advanced Functional Materials, 2020, 30(6):e1906343. DOI: 10.1002/adfm.201906343. Li D, He S, Wu Y, Liu J, Liu Q, Chang B, Zhang Q, Xiang Z, Yuan Y, Jian C, Yu A*, Cheng Z*. Excretable Lanthanide Nanoparticle for Biomedical Imaging and Surgical Navigation in the Second Near-Infrared Window. Advanced Science. 2019;6(23):1902042. Chen H, Wang J, Feng X, Zhu M, Hoffmann S, Hsu A, Qian K, Huang D, Zhao F, Liu W, Zhang H*, Cheng Z*. Mitochondria-targeted fluorescent molecules for high efficiency cancer growth inhibition and imaging. Chemical Science, 2019, 10, 7946 – 7951. He S, Chen S, Li D, Wu Y, Zhang X, Liu J, Song J, Liu L, Qu J*, Cheng Z.* A high affinity to skeleton rare earth doped nanoparticles for near-infrared II imaging. Nano Letters. 2019; 19(5):2985-2992. Sun Z, Cheng K, Yao Y, Wu F, Fung J, Chen H, Ma X, Tu Y, Xing L, Xia L*, Cheng Z*. Controlled Nano-Bio Interface of Functional Nanoprobes for in Vivo Monitoring Enzyme Activity in Tumors. ACS Nano. 2019, 13(2):1153-1167. Ma X, Wang S, Wang S, Liu D, Zhao X, Chen H, Kang F, Li G, Yang W, Wang J*, Cheng Z*. Biodistribution, Radiation Dosimetry, and Clinical Application of a Melanin Targeted PET Probe 18F-P3BZA in Patients. Journal of Nuclear Medicine. 2019; 60(1):16-22. Sun X, Xiao Z, Chen G, Han Z, Liu Y, Zhang C, Sun Y, Song Y, Wang K, Fang F, Wang X, Lin Y, Xu L, Shao L, Li J, Cheng Z*, Gambhir SS*, Shen B*. A PET imaging approach for determining EGFR mutation status for improved lung cancer patient management. Science Translational Medicine. 2018;10(431): eaan8840. He S, Song J*, Qu J*, Cheng Z.* Crucial Breakthrough of Second Near-infrared Biological Window Fluorophores: Design and Synthesis toward Multimodal Imaging and Theranostics. Chemical Society Review, 2018, 47(12): 4258 – 4278. Shou K, Tang Y, Chen H, Chen S, Zhang L, Zhang A., Fan Q*, Yu A*, Cheng Z*. Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery. Chemical Science, 2018; 9(12): 3105-3110. [Inside Front Cover Page Article]. Antaris AL, Chen H, Diao S, Ma Z, Zhang Z, Zhu S, Wang J, Lozano AX, Fan Q, Chew L, Zhu M, Cheng K, Hong X*, Dai H*, Cheng Z*. A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging. Nature Communications. 2017;8:15269. doi: 10.1038/ncomms15269. Cheng K, Chen H, Jenkins CH, Zhang G, Han F, Zhang Z, Fung J, Yang M, Jiang Y, Xing L*, Cheng Z*. Synthesis, Characterization and Biomedical Applications of a Novel Targeted Dual-Modal NIR-II Fluorescence and Photoacoustic Imaging Nanoprobe. ACS Nano, 2017, 11(12):12276-12291. Shou K, Qu C, Sun Y, Chen H, Chen S, Zhang L, Xu H, Hong X, Yu A*, Cheng Z*. Multifunctional biomedical imaging in physiological and pathological conditions using a NIR-II probe. Advanced Functional Materials. 2017, 27(23), 1700995. [Inside Back Cover Page Article]. Antaris AL, Chen H, Cheng K, Sun Y, Hong G, Qu C, Diao S, Deng Z, Hu X, Zhang B, Zhang X, Yaghi OK, Alamparambil ZR, Hong X*, Cheng Z*, Dai H*. A small-molecule dye for NIR-II imaging. Nature Materials. 2016;15(2):235-42. Sun Y, Hong SH, Ma X, Cheng K, Wang J, Zhang Z, Zeng X, Zhou H, Ding B, Yang M, Jiang Y, Hong X,* Cheng Z*. Recyclable Cu(I)/Melanin Dots for Cycloadditions, Bioconjugation and Cell Labeling. Chemical Science. 2016, 7: 5888-5892. Sun Y, Qu C, Chen H, He M, Tang C, Kang S, Yang M, Jiang Y, Ding B, Hong X*, Cheng Z* Novel benzo-bis(1,2,5-thiadiazole) fluorophores for in vivo NIR-II optical imaging. Chemical Science. 2016, 7: 6203-6207.