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个人简介

2018.02-至今 同济大学,生命科学与技术学院 教授 2012.10-2018.01 大连医科大学,肿瘤干细胞研究院 教授 2007.09-2012.07 北京协和医学院,北京生命科学研究所 生物化学与分子生物学博士 2003.09-2007.06 武汉大学,生命科学学院 理学学士

研究领域

1、非编码RNA在胚胎发育中的功能及调控机制 2、多能干细胞向生殖细胞定向分化的机制及应用 3、体细胞重编程的分子机制

干细胞生物学,发育生物学

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Zhu J, Chen K, Sun Y, Ye W, Liu J, Zhang D, Su N, Kou X, Zhao Y, Wang H, Gao S#, Kang L#. LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei. Nature Communications 14(1):957 (2023). (Correspondence author) Wu L, He S, Ye W, Shen J, Zhao K, Zhang Y, Zhang R, Wei J, Cao S, Chen K, Le R, Xi C, Kou X, Zhao Y, Wang H, Kang L#, Gao S#. Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress. Cell Proliferation 54(11):e13133 (2021). (Co-correspondence author) He J, Ye W, Kou N, Chen K, Cui B, Zhang X, Hu S, Liu T#, Kang L#, Li X#. MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway. Journal of Cellular and Molecular Medicine 24(1):841-849 (2020). (Co-correspondence author) Kang L*, Chen J*, Gao S. Historical review of reprogramming and pluripotent stem cell research in China.Yi Chuan 20;40(10):825-840 (2018). (First author) Wu L, Wu Y, Peng B, Hou Z, Dong Y, Chen K, Guo M, Li H, Chen X, Kou X, Zhao Y, Bi Y, Wang Y, Wang H, Le R, Kang L#, Gao S (2017) Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation.Stem Cell Reports 9(5):1692-1705 (Co-correspondence author) Li X, Ma C, Zhang L, Li N, Zhang X, He J, He R, Shao M, Wang J, Kang L#, Han C (2017)LncRNAAC132217.4, a KLF8-regulated long non-coding RNA, facilitates oral squamous cell carcinoma metastasis by upregulating IGF2 expression.Cancer Letter 407:45-56. (Co-correspondence author) Qin S, Yang D, Chen K, Li H, Zhang L, Li Y, Le R, Li X, Gao S and Kang L (2017)Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs.Oncotarget 8:84276-84284. (Co-correspondence author) Feng X, Xu X, Xiao X, Zou K, Yu W, Wu J, Tang R, Gao Y, Hao J, Zhao X, Liao Y, Chen Y, Huang W, Guo W, Kang L#, Deng W (2017)NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer.Cell Death & Disease 8(5):e2783. (Co-correspondence author) Wang M, Zhang Y, Wang T, Zhang J, Zhou Z, Sun Y, Wang S, Shi Y, Luan X, Zhang Y, Wang Y, Wang Y, Zou Z, Kang L#, Liu H (2015)The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.Cell Physiol Biochem 43(5):1755-1766. (Co-correspondence author) Hao J, Xu H, Luo M, Yu W, Chen M, Liao Y, Zhang C, Zhao X, Jiang W, Hou S, Feng X, Zou K, Chen Y, Huang W, Guo W, Kang L#, Deng W (2017)The tumor-promoting role of TRIP4 in melanoma progression and its involvement in response to BRAF-targeted therapy.J Invest Dermatol 138(1):159-170 (Co-correspondence author) Kang L, Gao S. Generation of Viable Mice from Induced Pluripotent Stem Cells (iPSCs) Through Tetraploid Complementation. Methods in Molecular Biology. 1330:125-32 (2015). (First author) Kang L#, Wu J, Tao Y, Li H,Liu X,Gao S, Wang Q (2015)Cell Type-Specific Expression Profile and Signaling Requirements in Early Hematopoietic Reprogramming.Stem Cells and Development 24(12):1483-92. (Co-correspondence author) Kang L, Gao S (2012)Pluripotency of induced pluripotent stem cells.J Anim Sci Biotechnol 2012 Feb 28;3(1):5 Kang L, Wu T, Tao Y, Yuan Y, He J, Zhang Y, Luo T, Kou Z, Gao S (2011)Viable mice produced from three-factor induced pluripotent stem (iPS) cells through tetraploid complementation.Cell Research 21(3):546-9. Kang L, Kou Z, Zhang Y, Gao S (2010)Induced pluripotent stem cells (iPSCs)--a new era of reprogramming.Journal of Genetics and Genomics 7(7):415-21. Kou Z*, Kang L*, Yuan Y, Tao Y, Zhang Y, Wu T, He J, Wang J, Liu Z, Gao S (2010)Mice cloned from induced pluripotent stem cells (iPSCs).Biology of Reproduction 83(2):238-43. (Co-first author) Kang L, Wang J, Zhang Y, Kou Z, Gao S (2009)iPS cells can support full term development of tetraploid blastocyst-complemented embryos.Cell Stem Cell 5(2):135-138.

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