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个人简介

史兴杰,统计学院、统计交叉科学研究院副教授,博士生导师。2014年获得上海财经大学统计学博士学位,期间2012.9-2014.5在耶鲁大学生物统计系联合培养。主要研究方向是组学遗传学数据融合、生物医学大数据统计建模、统计计算。在Nucleic Acids Research、Nature Communications、Bioinformatics等期刊发表学术论文30余篇,主持国家自然科学基金2项和上海市面上项目1项。国际统计学会当选会员、中国现场统计研究会理事。 工作经历 2023.06 - 华东师范大学 统计学院 2021.06 - 华东师范大学 统计交叉科学研究院 教育经历 2009.09 - 2014.09 上海财经大学统计与管理学院统计学博士 2012.09 - 2014.05 美国耶鲁大学生物统计系联合培养 荣誉及奖励 上海市优秀博士学位论文 首届《统计研究》优秀论文三等奖 “第十一届全国大学生市场调查与分折大赛总决赛”一等奖的优秀指导教师

研究领域

主要包括生物医学大数据融合和海洋大数据融合的统计机器学习方法。 在生物医学领域,随着高通量测序技术的应用,生物医学大数据的涌现为验证旧发现、发现新规律和产生新知识提供了前所未有的机遇。面对大规模、高通量、高噪声的数据挑战,我们采用统计机器学习方法结合生物信息学技术,融合组学与遗传学大数据,实现从细胞到组织的生物学功能在时空尺度上的解析。 同时,我们最近开始探索海洋大数据融合,通过研究数据融合和统计机器学习方法,将多源现场观测和海洋模式相结合,建立高时空分辨率的三维温盐流场数据集,服务于西太多圈层相互作用数据集成研究。

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Shi, X.*,#; Yang, Y.#; Ma X.S; Zhou Y.; Guo Z.; Wang C.; Liu J.* (2023) Probabilistic cell/domain-type assignment of spatial transcriptomics data with SpatialAnno, Nucleic Acids Research, gkad1023 Zhang, X.S; Liu, X.; Shi, X.* (2023) Model Selection for Varying Coefficient Nonparametric Transformation Model, Econometric Journal, 26(3), 492-512 Zhang, X.S; Shi, X.*; Liu, Y.; Liu, X.; Ma, S. (2023) A General Framework for Identifying Hierarchical Interactions and Its Application to Genomics Data, Journal of Computational and Graphical Statistics, 32(3), 873-883 Liu W.; Liao X; Luo Z.; Yang Y.; Lau M.; Jiao Y.; Shi X.; Zhai W.; Ji H.; Yeong J.; Liu J. (2023) Probabilistic embedding, clustering, and alignment for integrating spatial transcriptomics data with PRECAST, Nature Communications, 14(296), doi: 10.1038/s41467-023-35947-w Liu, W.; Liao, X.; Yang, Y.; Lin, H.; Yeong , J.; Zhou, X.*; Shi,X. *; Liu J.* (2022) Joint dimension reduction and clustering analysis of single-cell RNA-seq and spatial transcriptomics data, Nucleic Acids Research, 50(12), gkac219 Yang, Y.#; Shi, X.#; Zhou, Q.; Sun, L.; Yeong, J.?, Liu, J.? (2022) SC-MEB: spatial clustering with hidden Markov random field using empirical Bayes, Briefing in Bioinformatics, 23(1): bbab466 Cheng, Q.; Qiu, T.; Chai, X.; Sun, B.; Xia, Y.; Shi, X.*; Liu, J.* (2022) MR-Corr2: A two-sample Mendelian randomization method that accounts for correlated horizontal pleiotropy using correlated instrumental variants, Bioinformatics, 38(2): 303-310 Shi, X. and Chai, X. and Yang, Y. and Cheng, Q. and Jiao, Y. and Chen, H. and Huang, J. and Yang, C. and Liu, J. (2020) A tissue-specific collaborative mixed model for jointly analyzing multiple tissues in transcriptome-wide association studies. Nucleic Acids Research, 48(19): e109 [SCI, Impact Factor: 17] Cheng Q., Yang Y., Shi X., Yeung K., Yang C., Peng H., Liu J. (2020). MR-LDP: a two-sample Mendelian randomization for GWAS summary statistics accounting for linkage disequilibrium and horizontal pleiotropy. NAR Genomics and Bioinformatics, 2(2):lqaa028 Shi, X. and Ma, S. and Huang, Y. (2020). Promoting sign consistency in the Cox proportional hazards curemodel selection.Statistical Methods in Medical Research,29(1):15-28. [SCI] Yang Y., Shi X., Jiao Y., Huang J., Chen M., Zhou X., Sun L., Lin X., Yang C. and Liu J. (2020) CoMM-S2: a collaborative mixed model using summary statistics in transcriptome-wide association studies. Bioinformatics, 36(7): 2009-16[SCI] Liao X., Chai X., Shi X., Chen L., Liu J.(2020) The statistical practice of the GTEx Project: from single to multiple tissues. Quantitative Biology [SCI] 史兴杰,王赛旎,李扬. (2020). 高维数据的稳健二分类方法. 统计研究.37(9):95-105 张晶,方匡南*,张喆,史兴杰,郑陈璐. (2020). 基于稀疏结构连续比率模型的消费金融风控研究. 统计研究. 37(11):57-67 Shi, X. and Yang Y. and Jiao Y. and Cheng C. and Yang C. and Lin X. and Liu J. (2019). VIMCO: variational inference for multiple correlated outcomes in genome-wide association studies. Bioinformatics, 35(19), 3693-3700. [SCI] S. Wang, X. Shi, M. Wu, and S. Ma (2019) Horizontal and vertical integrative analysis methods for mental disorders omics data. Scientific Report, 9(1):13430 [SCI] 孙怡凡,吴梦云,史兴杰. (2019).高维大数据基因网络中的社区发现——以NC方法为例. 统计研究, 36(3), 124-128. Shi, X., Huang, Y. and Huang, J and Ma, S. (2018). A forward and backward stagewise algorithm for nonconvex loss functions and adaptive lasso. Computational Statistics and Data Analysis, 124, 235-251. Chai, H*. and Shi, X.* and Zhang, Q and Zhao, Q and Huang, Y and Ma, S. (2017). Analysis of cancer gene expression data with an assisted robust marker identification approach. Genetic Epidemiology,41, 779– 789. [SCI] Liu, J. and Yang, C. and Shi, X. and Li, C. and Huang, J. and Zhao, H. and Ma, S. (2016). Analyzing Association Mapping in Pedigree‐Based GWAS Using a Penalized Multitrait Mixed Model. Genetic Epidemiology, 40(5), 382-393. [SCI] Jiang, Y*. andShi, X. * and Zhao, Q. and M. Krauthammer and BE Rothberg and Ma, S. (2016). Integrated analysis ofmultidimensional omics data on cutaneous melanoma prognosis. Genomics,107(6), 223-30. Shi, X. and Zhao, Q. and Huang, J. and Xie, Y. and Ma, S. (2015). Deciphering the association between gene expression and copy number alteration using a sparse double Laplacian shrinkage approach. Bioinformatics, 31(24), 3977-3983. [SCI] Shi, X. * and Yi, H* and Ma, S. (2015). Measures for the degree of overlap of gene signatures and applications to TCGA. Briefings in Bioinformatics,16(5), 735-744. [SCI] Wu, C. and Shi, X. and Cui, Y. and Ma, S. (2015). A penalized robust semiparametric approach for gene–environment interactions. Statistics in Medicine, 34(30), 4016-30. [SCI] Zhao, Q.* and Shi, X.* and Xie, Y. and Huang, J. and Ben-Chang Shia and Ma, S. (2015). Combining Multidimensional Genomic Measurements for Predicting Cancer Prognosis: Observations from TCGA. Briefing in Bioinformatics, 16(2), 291-303. [SCI] Zhao, Q. and Shi, X. and Huang, J. and Liu, J. and Li, Y. and Ma, S. (2015). Integrative analysis of -omics data using penalty functions. WIREs Computational Statistics,7(1), 99-108. Shi, X. and Liu, J. and Huang, J. and Zhou, Y. and Ben-Chang Shia and Ma, S. (2014). Integrative Analysis of Cancer Prognosis Data with Contrasted Group Bridge Penalization. Genetic Epidemiology, 38(2), 141-151. [SCI] Shi,X. and Liu, J. and Huang, J. and Zhou, Y. and Xie, Y. and Ma, S. (2014). A Penalized Robust Method for Identifying Gene-Environment Interactions. Genetic Epidemiology, 38(3), 220-230. [SCI] Shi, X. and Shen, S. and Liu, J. and Huang, J. and Zhou, Y. and Ma, S.(2014). Similarity of Markers Identified from Cancer Gene Expression Studies: Observations from GEO. Briefing in Bioinformatics, 15(5), 671-684. [SCI]

学术兼职

国际统计学会推选会员(ISI Elected member) 中国现场统计研究会理事 中国优选法统筹法与经济数学研究会数据科学分会理事 现场统计研究会环境与资源统计学会理事

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