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研究领域

Our work focuses on the identification of molecular pathways and neuronal networks involved in the development of social skills, and their breakdown in pathological conditions. We use a combination of genetic, behavioural, molecular and imaging methods in wild type and genetic mouse models carrying mutations associated with different pathological conditions, in particular autism or schizophrenia.

近期论文

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Baudouin, S. J. 2014. Heterogeneity and convergence: the synaptic pathophysiology of autism. European Journal of Neuroscience 39(7), pp. 1107-1113. (10.1111/ejn.12498) Louveau, A.et al. 2013. Impaired spatial memory in mice lacking CD3ζ is associated with altered NMDA and AMPA receptors signaling independent of T-cell deficiency. The Journal of Neuroscience 33(47), pp. 18672-18685. (10.1523/JNEUROSCI.3028-13.2013) pdf Baudouin, S. J. 2013. Apport des modèles murins dans l'autisme syndromique et non syndromique. médecine/sciences 29(2), pp. 121-123. (10.1051/medsci/2013292002) pdf Budreck, E.et al. 2013. Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling. Proceedings of the National Academy of Sciences of the United States of America 110(2), pp. 725-730. (10.1073/pnas.1214718110) Baudouin, S.et al. 2012. Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism. Science 338(6103), pp. 128-132. (10.1126/science.1224159) Angibaud, J.et al. 2011. The immune molecule CD3zeta and its downstream effectors ZAP-70/Syk mediate ephrin signaling in neurons to regulate early neuritogenesis. Journal of Neurochemistry 119(4), pp. 708-722. (10.1111/j.1471-4159.2011.07469.x) Angibaud, J.et al. 2011. Ectopic expression of the immune adaptor protein CD3zeta in neural stem/progenitor cells disrupts cell-fate specification. Journal of Molecular Neuroscience 46(2), pp. 431-441. (10.1007/s12031-011-9607-2) Baudouin, S.et al. 2008. The signaling adaptor protein CD3ζ is a negative regulator of dendrite development in young neurons. Molecular Biology of the Cell 19(6), pp. 2444-2456. (10.1091/mbc.E07-09-0947) pdf Baudouin, S.et al. 2006. Dendrite-selective redistribution of the chemokine receptor CXCR4 following agonist stimulation. Molecular and Cellular Neuroscience 33(2), pp. 160-169. (10.1016/j.mcn.2006.07.007)

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