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Ph.D., University of Southern California, 1984 Graduate Faculty Status

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Schoffstall, B., N. M. Brunet, F. Wang, S. Williams, A. T. Barnes, V. F. Miller, L. A. Compton, L. A. McFadden, D. W. Taylor, R. Dhanarajan, M. Seavy, and P. B. Chase (2006) Ca2+ sensitivity of regulated cardiac thin filament sliding does not depend on myosin isoform. Journal of Physiology 577: 935-944. (pdf) (HTML full text) (abstract) Schoffstall, B., A. Clark, and P. B. Chase (2006) Positive inotropic effects of low dATP/ATP ratios on mechanics and kinetics of porcine cardiac muscle. Biophysical Journal 91: 2216-2226. (pdf) (abstract) Huang, L., P. Manandhar, K. Byun, P. B. Chase, and S. Hong (2006) Selective assembly and alignment of actin filaments with desired polarity on solid substrates. Langmuir 22: 8635-8638. (pdf) (HTML full text) (abstract) Moreno-Gonzalez , A., T. E. Gilles, A. J. Rivera, P. B. Chase, D. A. Martyn, and M. Regnier (2007) Thin filament regulation of force redevelopment kinetics in rabbit skeletal muscle fibres. Journal of Physiology 579: 313-326. (pdf) (abstract) Kataoka, A., B. C. Tanner, J. M. Macpherson, X. Xu, Q. Wang, M. Regnier, T. L. Daniel, and P. B. Chase (2007) Spatially explicit, nano-mechanical models of the muscle half-sarcomere: Implications for biomechanical tuning in atrophy and fatigue. Acta Astronautica 60: 111-118. (pdf) (HTML full text) Kataoka, A., C. Hemmer, and P. B. Chase (2007) Computational simulation of hypertrophic cardiomyopathy mutations in troponin I: influence of increased myocyte calcium sensitivity on isometric force, ATPase and [Ca2+]i. Journal of Biomechanics 40: 2044-2052. (pdf) (abstract) Chase, P. B. (2007) Tropomyosin in the groove? Molecular insights into an inherited myopathy. Journal of Physiology 581: 889. (pdf) (HTML full text) Byun, K., M. Kim, P. B. Chase, and S. Hong (2007) Selective assembly and guiding of actomyosin using carbon nanotube network monolayer patterns. Langmuir 23: 9535-9539. (pdf) (abstract) Schoffstall, B., and P. B. Chase (2008) Increased intracellular [dATP] enhances cardiac contraction in embryonic chick cardiomyocytes. Journal of Cellular Biochemistry 104: 2217-2227. (pdf) (PubMed Central (open access)) (abstract) Manandhar, P., K. Chen, K. Aledealat, G. Mihajlovi??, C. S. Yun, M. Field, G. S. Sullivan, G. F. Strouse, P. B. Chase, S. von Molnar, and P. Xiong (2009) The detection of specific biomolecular interactions with micro-Hall magnetic sensors. Nanotechnology 20: 355501. (pdf) (abstract) Butcher, M. T., P. B. Chase, J. W. Hermanson, A. M. Clark, N. N. Brunet, and J. E. Betram (2010) Contractile properties of muscle fibers from the forelimb deep and superficial digital flexors of horses. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 299: R996-R1005. (pdf) (PubMed Central (open access)) (abstract) Aledealat, K., G. Mihajlovi??, K. Chen, M. Field, G. J. Sullivan, P. Xiong, P. B. Chase, and S. von Molnar (2010) Dynamic micro-Hall detection of superparamagnetic beads in a microfluidic channel. Journal of Magnetism and Magnetic Materials 322: L69-L72. (pdf) (HTML full text) Bai, F., A. Weis, A. K. Takeda, P. B. Chase, and M. Kawai (2011) Enhanced active cross-bridges during diastole: molecular pathogenesis of tropomyosins HCM mutations. Biophysical Journal 100: 1014-1023. (HTML full text) (abstract) Mathur, M. C., P. B. Chase, and J. M. Chalovich (2011) Several cardiomyopathy causing mutations on tropomyosin either stabilize the inactive state or actomyosin or alter the binding properties of tropomyosin. Biochemical and Biophysical Research Communications 406: 74-78. (pdf) (HTML full text) Cheng, Y., K. Chen, N. L. Meyer, J. Yuan, L. S. Hirst, P. B. Chase, and P. Xiong (2011) Functionalized SnO2 nanobelt field-effect transistor sensors for label-free detection of cardiac troponin. Biosensors and Bioelectronics 26: 4538-4544. (HTML full text) Schoffstall, B., V. A. LaBarbera, N. M. Brunet, B. J. Gavino, L. Herring, S. Heshmati, B. H. Kraft, V. Inchausti, N. L. Meyer, D. Moonoo, A. K. Takeda, and P. B. Chase (2011) Interaction between troponin and myosin enhances contractile activity of myosin in cardiac muscle. DNA and Cell Biology 30: 653-659. (PubMed Central (open access)) (abstract) Asumda, F. Z., and P. B. Chase (2011) Age-related changes in rat bone marrow mesenchymal stem cell plasticity. BMC Cell Biology 12: 44. (open access) Wang, F., N. M. Brunet, J. R. Grubich, E. Bienkiewicz, T. M. Asbury, L. A. Compton, G. Mihajlovi?, V. F. Miller, and P. B. Chase (2011) Facilitated cross-bridge interactions with thin filaments by familial hypertrophic cardiomyopathy mutations in α-tropomyosin. Journal of Biomedicine and Biotechnology 2011: 435271. (open access) Asumda, F. Z., and P. B. Chase (2012) Nuclear cardiac troponin and tropomyosin are expressed early in cardiac differentiation of rat mesenchymal stem cells. Differentiation 83: 106-115. (HTML full text) Chase, P. B., S. Hong, A. Mansson, and P. Xiong (2012) Editorial: Bionanotechnology and Nanomedicine. Journal of Biomedicine and Biotechnology 2012: 763967. (open access) Hira, S. M., K. Aledealat, K. Chen, M. Field, G. J. Sullivan, P. B. Chase, P. Xiong, S. von Molnar, and G. F. Strouse (2012) Detection of target ssDNA using a micro-fabricated Hall magnetometer with correlated optical readout. Journal of Biomedicine and Biotechnology 2012: 492730. (open access) Brunet, N. M., G. Mihajlovi??, K. Aledealat, F. Wang, P. Xiong, S. von Molnar, and P. B. Chase (2012) Micro-mechanical thermal assays of Ca2+-regulated thin filament function and modulation by hypertrophic cardiomyopathy mutants of human cardiac troponin. Journal of Biomedicine and Biotechnology 2012: 657523. (open access) Loong, C. K., M. A. Badr, and P. B. Chase (2012) Tropomyosin flexural rigidity and single Ca2+ regulatory unit dynamics: implications for cooperative regulation of cardiac muscle contraction and cardiomyocyte hypertrophy. Frontiers in Physiology (Frontiers in Striated Muscle Physiology) 3: 80. [equal contributions by Loong and Badr](open access) Loong, C. K., H. Zhou, and P. B. Chase (2012) Persistence length of human cardiac α-tropomyosin measured by single molecule direct probe microscopy. PLoS One 7: e39676. (open access) Loong, C. K., H. Zhou, and P. B. Chase (2012) Familial hypertrophic cardiomyopathy related E180G mutation increases flexibility of human cardiac α-tropomyosin. FEBS Letters 586: 3503-3507.

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