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个人简介

工作经历 2015.9-至今,中国科学技术大学生命科学学院,教授 学习经历 2001-2005,中国科学技术大学,学士,高分子化学与物理,导师:王均教授 2005-2010,中国科学技术大学,博士,高分子化学与物理,导师:王均教授 2010,美国华盛顿圣路易斯大学生物医学工程系,博士后,导师:夏幼南教授 2011,美国佐治亚理工学院生物医学工程系,博士后,导师:夏幼南教授 2012-2015,美国芝加哥大学James Franck研究所,博士后,导师:田博之教授 所获奖励 2016年,中-韩生物材料协会青年科学家奖 2018年,全球纳米生物领域45位45岁以下(45 under 45)青年科学家奖

研究领域

纳米药物,生物材料,生物医用高分子,显微活体成像

近期论文

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S. Li, Q. Wang, Y. Shen, M. Hassan, J. Shen, W. Jiang, Y. Su, J. Chen, L. Bai, W. C. Zhou, Y. C. Wang.* Pseudoneutrophil Cytokine Sponges Disrupt Myeloid Expansion and Tumor Trafficking to Improve Cancer Immunotherapy. Nano Letters, 2019, in press. Y. Ma,# Y. Zhang,# X. Li,# Y. Zhao, M. Li, W. Jiang, X. Tang, J. Dou, L. Lu, F. Wang,* Y. C. Wang.* Near-Infrared II Phototherapy Induces Deep Tissue Immunogenic Cell Death and Potentiates Cancer Immunotherapy. ACS Nano, 2019, 13, 11967-11980. Y. Ma,# Y. Zhao,# N. K. Bejjanki,# X. Tang, W. Jiang, J. Dou, M. I. Khan, Q. Wang, J. Xia, H. Liu, Y. You, G. Zhang, Y. C. Wang,* J. Wang. Nanoclustered Cascaded Enzymes for Targeted Tumor Starvation and Deoxygenation-Activated Chemotherapy without Systemic Toxicity. ACS Nano, 2019, 13, 8890-8902. P. Chen,# Y. Ma,# Z. Zheng,# C. Wu, Y. C. Wang,* G. L. Liang,* Facile Syntheses of Conjugated Polymers for Photothermal Tumour Therapy. Nature Communications, 2019, 10:1192. Y. Zhang,# Y. Zhao,# J. Shen,# X. Sun, Y. Liu, L. Hang, H. Liu, Y. C. Wang,* J. Wang Nanoenabled Modulation of Acidic Tumor Microenvironment Reverses Anergy of Infiltrating T Cells and Potentiates Anti-PD-1 Therapy. Nano Letters, 2019, 19, 2774-2783. W. Jiang,# Z. Zhang,# Q. Wang,# J. Dou, Y. Zhao, Y. Ma, H. Liu, H. X. Xu,* Y. C. Wang.* Tumor Reoxygenation and Blood Perfusion Enhanced Photodynamic Therapy using Ultrathin Graphdiyne Oxide Nanosheets. Nano Letters, 2019, 19, 4060-4067. Y. Liu,# N. K. Bejjanki,# W. Jiang, Y. Zhao, L. Wang, X. Sun, X. Tang, H. Liu,* Y. C. Wang.* Controlled Syntheses of Well-Defined Poly(thionophosphoester)s that Undergo Peroxide-Triggered Degradation. Macromolecules, 2019, 52, 4306-4316. H. Wang, Y. Hou, Y. Hu, J. Dou, Y. Shen, Y. C. Wang,* H. Lu.* Enzyme-Activatable Interferon-Poly(α-amino acid) Conjugates for Tumor Microenvironment Potentiation. Biomacromolecules, 2019, 20, 3000-3008. L Yang, X Chen, L Wang, Z Hu, N Xin, M Hippler, W Zhu, Y Hu, J Li, Y. C. Wang, L Zhang, D Wu, J Chu. Targeted Single-Cell Therapeutics with Magnetic Tubular Micromotor by One-Step Exposure of Structured Femtosecond Optical Vortices. Advanced Functional Materials, 2019, in press. W. Huang, X. Zhang, B. Chen, H. Miao, C. O. Trindle, Y. C. Wang, Y. Luo, G. Zhang.* Boosting the Triplet Activity of Heavy-Atom-Free Difluoroboron Dibenzoylmethane via sp3 Oxygen-Bridged Electron Donors. Chemical Communications, 2019, 55, 67-70 H. Huang, T. Wu, H. Shi, Y. Wu, H. Yang, K. Zhong, Y. C. Wang, Y. Liu.* Modular Design of Nanobody-Drug Conjugates for Targeted-Delivery of Platinum Anticancer Drug with MRI Contrast Agent. Chemical Communications, 2019, 55, 5175-5178. B. Chen, X. Zhang, Y. C. Wang, H. Miao, G. Zhang.* Aggregation-Induced Emission with Long-Lived Room-Temperature Phosphorescence from Methylene-Linked Organic Donor-Acceptor Structures, Chemistry-An Asian Journal, 2019, 14, 751-754. W. Jiang,# Q. Li,# L. Xiao,# J. Dou, Y. Liu, W. Yu, Y. Ma, X. Li, Y. You, Z. Tong, H. Liu, H. Liang, L. Lu, X. Xu, Y. Yao,* G. Zhang,* Y. C. Wang,* J. Wang. Hierarchical Multiplexing Nanodroplets for Imaging-Guided Cancer Radiotherapy via DNA Damage Enhancement and Concomitant DNA Repair Prevention. ACS Nano, 2018, 12, 5684-5698. X. Wang,# Y. Ma,# X. Sheng, Y. C. Wang,* H. Xu.* Ultrathin Polypyrrole Nanosheets via Space-Confined Synthesis for Efficient Photothermal Therapy in the Second Near-Infrared Window. Nano Letters, 2018, 18, 2217-2225. W. Jiang,# Q. Li,# Z. Zhu,# Q. Wang, J. Dou, Y. Zhao, W. Lv, F. Zhong, Y. Yao, G. Zhang, H. Liu,*Y. C. Wang,* J. Wang. Cancer Chemoradiotherapy Duo: Nano-Enabled Targeting of DNA Lesion Formation and DNA Damage Response. ACS Applied Materials & Interfaces, 2018, 10, 35734-35744. Z. Ruan,# Y. Zhao,# P. Yuan, L. Liu, Y. C. Wang,* L. Yan.* PEG Conjugated BODIPY-Br2 as Macrophotosensitizer for Efficient Imaging-Guided Photodynamic Therapy. Journal of Materials Chemistry B, 2018, 6, 753-762. L. Huang, B. Chen, X. Zhang, C. Trindle, F. Liao, Y. C. Wang, H. Miao, Y. Luo, G. Zhang.* Proton-Activated "Off-On" Room-Temperature Phosphorescence from Purely Organic Thioethers. Angewandte Chemie International Edition, 2018, 57, 16046-16050. X. Du, J. Wang, S Iqbal, H. Li, Z. Cao, Y. C. Wang, J. Du, J Wang.* The Effect of Surface Charge on Oral Absorption of Polymeric Nanoparticles. Biomaterials Science, 2018, 6, 642-650. Z. Zhao,# J Long,# Y. Zhao, J. Yang, W Jiang, Q. Liu, K Yan, L Li, Y. C. Wang.* and Z. X. Lian.* Adaptive Immune Cells are Necessary for the Enhanced Therapeutic Effect of Sorafenib-Loaded Nanoparticles. Biomaterials Science, 2018, 6, 893-900. W. Jiang, J. Wang, J. Yang, Z. He, G. Zhang, F. Huang, X. Zhou, L.F. Yan,* X. Z. Yang,*Y. C. Wang,* J. Wang. Acidity-Triggered TAT-Presenting Nanocarriers Augment Tumor Retention and Nuclear Translocation of Drugs. Nano Research,2018, 11, 5716-5734.

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