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个人简介

男,1979-10,肿瘤学博士,副研究员,硕士生导师。 2003.7获浙江大学医学院医学学士学位,同年进入浙江大学医学院肿瘤研究所学习,导师为教育部长江学者胡讯教授,2008.7年获肿瘤学博士学位,博士论文获全国优秀博士论文提名奖。2008-8进入浙江大学医学院附属邵逸夫医院肿瘤内科工作至今。2011.4至2012.10赴美国City of Hope Medical Center合作研究,

研究领域

自噬在肿瘤发生发展及抗肿瘤治疗过程中的作用。目前主持国家青年自然基金:一类necroptosis诱导剂抗肿瘤干细胞研究

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Han W, Li L, Qiu S, Lu Q, Pan Q, Gu Y, Luo J, Hu X. Shikonin circumvents cancer multidrug resisatnce by induction of necroptosis. Molecular Cancer Therapeutics. 2007;6(5);1641- 1649. 2. Li L, Han W*, Gu Y, Qiu S, Lu Q, Jin J, Luo J, Hu X. Honokiol induces a necrotic cell death through mitochondrial permeability transition pore. Cancer Research. 2007;67 (10);4894-4903. *共同第一作者。 3. Hu X, Han W, Li L. Targeting the Weak Point of Cancer by Induction of Necroptosis. Autophagy. 2007;3(5);490-492. 4. Zhang K, Han W*, Zhang R, Xu X, Pan Q, Hu X. Phenylobacterium zucineum sp. nov., a facultative intracellular bacterium isolated from a human erythroleukemia cell line K562. Systematic and applied microbiology. 2007;30(3);207-212. *共同第一作者。 5. Li L, Pan Q, Han W, Liu Z, Li L, Hu X. Schisandrin B Prevents Doxorubicin-induced Cardiotoxicity via Enhancing Glutathione Redox Cycling. Clinical Cancer Research. 2007; 13(22):6753-6760. 6. Han W, Xie J, LI L, Liu z, Hu X. Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis. Apoptosis. 2009,May,01;14(5):674-86. 7.Han W, Pan H, Chen Y, Sun J, Wang Y, et al. EGFR Tyrosine Kinase Inhibitors Activate Autophagy as a Cytoprotective Response in Human Lung Cancer Cells. PLoS ONE 2011 6(6): e18691. doi:10.1371/journal.pone.0018691. 8. Han W, Sun J, Feng L, Wang K, Li D, et al. Autophagy Inhibition Enhances Daunorubicin- Induced Apoptosis in K562 Cells. PLoS ONE 2011 6(12): e28491. doi:10.1371/journal. pone. 0028491. 9. Wang Y, Ding L, Wang X, Zhang J, Han W, Feng L, Sun J, Jin H, Wang XJ. Pterostilbene simultaneously induces apoptosis, cell cycle arrest and cyto-protective autophagy in breast cancer cells. Am J Transl Res. 2012;4(1):44-51. Epub 2012 Jan 5. 10.Han, W.; Xie, J.; Fang, Y.; Wang, Z.; Pan, H. Nec-1 Enhances Shikonin-Induced Apoptosis in Leukemia Cells by Inhibition of RIP-1 and ERK1/2. Int. J. Mol. Sci. 2012, 13, 7212-7225.

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