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个人简介

教育经历 2003.09-2006.07 博士,中国农业大学,预防兽医学 1998.09-2001.07 硕士,中国农业大学,预防兽医学 1994.09-1998.07 本科,中国农业大学,兽医学专业 工作经历 2020.12- 教授,中国农业大学动物医学院预防兽医学系 2012.12-2020.11 研究员,中国农业大学动物医学院预防兽医学系 2006.12-2012.11 副研究员,中国农业大学动物医学院预防兽医学系 2001.07-2006.11 助教、讲师,中国农业大学动物医学院预防兽医学系 获奖及荣誉 2022 入选教育部“国家高层次人才奖励计划” 2021 第七届中国国际“互联网+”大学生创新创业大赛优秀创新创业导师 2021 中国农业大学教学成果奖特等奖(2/10) 2021 中国农业大学优秀教师 2020 中国农业大学校级代表性科研成果与重大社会服务贡献奖 2020 中国农业大学研究生教育成果奖二等奖(1/6) 2019 中国农业大学优秀共产党员 2018 中国学位与研究生教育学会研究生教育成果奖二等奖(4/5) 2018 中国农业大学研究生教育成果奖特等奖(4/6) 2017 中国农业大学优秀党务工作者 2015 山东省科技进步一等奖(3/12)

研究领域

针对鸡传染性支气管炎病毒(IBV)、新城疫病毒(NDV)等家禽重要呼吸道病原,开展流行病学、感染与致病机理、传播与免疫机制以及新型疫苗创制等研究工作。

近期论文

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Li X, Zhao Y, Teng QY, Zhang XH, Xue J, Zhang GZ*. 2023. Methyltransferase K-D-K-E motif influences the intercellular transmission of Newcastle disease virus. Virulence 14(1):2186336. Zhao J, Feng DL, Zhao Y, Huang M, Zhang XH, Zhang GZ*. 2022. Role of stress granules in suppressing viral replication by the infectious bronchitis virus endoribonuclease. Journal of Virology 96(12):e0068622. Zhao Y, Liang R, Cheng JL, Zhao J, Xue J, Zhang GZ*. 2022. Attenuated viral replication of avian infectious bronchitis virus with a novel 82-nucleotide deletion in the 5a gene indicates a critical role for 5a in virus-host interactions. Microbiology Spectrum 10(4):e0140522. Qin YF, Teng QY, Feng D, Pei Y, Zhao Y, Zhang GZ*. 2022. Development of a nanoparticle multiepitope DNA vaccine against virulent infectious bronchitis virus challenge. Journal of Immunology 208(6):1396-1405. Zhao J, Sun L, Zhao Y, Feng DL, Cheng JL, Zhang GZ*. 2021. Coronavirus endoribonuclease ensures efficient viral replication and prevents protein kinase R activation. Journal of Virology 95(7): e02103-20. Yang YL, Xue J, Teng QY, Li X, Bu YW, Zhang GZ*. 2021. Mechanisms and consequences of Newcastle disease virus W protein subcellular localization in the nucleus or mitochondria. Journal of Virology 95(7):e02087-20. Cheng JL, Zhao Y, Hu YX, Zhao J, Xue J, Zhang GZ*. 2021. The furin-S2' site in avian coronavirus plays a key role in central nervous system damage progression. Journal of Virology 95(11):e02447-20. Qin YF, Tu KH, Teng QY, Feng DL, Zhao Y, Zhang GZ*. 2021. Identification of novel T-cell epitopes on infectious bronchitis virus N protein and development of a multi-epitope vaccine. Journal of Virology 95(17):e0066721. Wu YF, Wang Y, Yang HM, Li Q, Gong X, Zhang GZ*, Zhu K*. 2021. Resident bacteria contribute to opportunistic infections of the respiratory tract. PLoS Pathogens 17(3):e1009436. Gao L, Zhou J, Yang S, Wang L, Chen X, Yang Y, Li R, Pan Z, Zhao J, Li Z, Huang Q, Tang J, Hu L, Liu P, Zhang GZ*, Chen Y*, Ye L*. 2021. The dichotomous and incomplete adaptive immunity in COVID-19 patients with different disease severity. Signal Transduction and Targeted Therapy 6(1):113. Shao L, Zhao J, Li LH, Huang XY, Yang HM, Cheng JL, Liu CQ, Zhang GZ*. 2020. Pathogenic characteristics of a QX-like infectious bronchitis virus strain SD in chickens exposed at different ages and protective efficacy of combining live homologous and heterologous vaccination. Veterinary Research 51:86. Chen X, Pan Z, Yue S, Yu F, Zhang J, Yang Y, Li R, Liu B, Yang X, Gao L, Li Z, Lin Y, Huang Q, Xu L, Tang J, Hu L, Zhao J, Liu P, Zhang GZ*, Chen Y*, Deng K*, Ye L*. 2020. Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19. Signal Transduction and Targeted Therapy 5(1):180. Yang YL, Bu YW, Zhao J, Xue J, Xu G, Song Y, Zhao Y, Yang HM, Zhang GZ*. 2019. Appropriate amount of W protein of avian avulavirus 1 benefits viral replication and W shows strain-dependent subcellular localization. Virology 538:71-85. Cheng JL, Zhao Y, Xu G, Zhang KR, Jia WF, Sun YL, Zhao J, Xue J, Hu YX, Zhang GZ*. 2019. The S2 subunit of QX-type infectious bronchitis coronavirus spike protein is an essential determinant of neurotropism. Viruses 11:972. Song Y, Pei Y, Yang YL, Xue J, Zhang GZ*. 2019. The Ntail region of nucleocapsid protein is associated with the pathogenicity of pigeon paramyxovirus type 1 in chickens. Journal General Virology 100(6):950-957. Yu XH, Cheng JL, He ZR, Li C, Song Y, Xue J, Yang HM, Zhang R, Zhang GZ*. 2017. The glutamic residue at position 402 in the C-terminus of Newcastle disease virus nucleoprotein is critical for the virus. Scientific Reports 7(1):17471. Yan SH, Liu XY, Zhao J, Xu G, Zhao Y, Zhang GZ*. 2017. Analysis of antigenicity and pathogenicity reveals major differences among QX-like infectious bronchitis viruses and other serotypes. Veterinary Microbiology 203:167-173. Yang HM, Zhao J, Xue J, Yang YL, Zhang GZ*. 2017. Antigenic variation of La Sota and genotype VII Newcastle disease virus (NDV) and their efficacy against challenge with velogenic NDV. Vaccine 35(1):27-32. Zhao Y, Zhang H, Zhao J, Zhong Q, Jin JH, Zhang GZ*. 2016. Evolution of infectious bronchitis virus in China over the past two decades. Journal General Virology 97:1566-1574. Feng JL, Hu YX, Ma ZJ, Yu Q, Zhao JX, Liu XD, Zhang GZ*. 2012. Virulent avian infectious bronchitis virus, People's Republic of China. Emerging Infectious Diseases 18(12):1994-2001.

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