个人简介
教育与科研经历
1996年毕业于北京师范大学生物系，1999年取得分子细胞生物学硕士学位。
2006年在美国罗彻斯特大学生物系取得分子、细胞和发育生物学博士学位。
2006-2012年在加州大学圣地亚哥分校进行博士后研究，期间获得癌症研究所博士后奖学金。
2013年加入中国科学技术大学生命科学学院。
多年来一直从事基因表达调控、表观遗传学，ncRNA，基因组相互作用等相关研究，在 GenesDev. 、Mol Cell Biol.、Nature、PNAS 等
学术期刊上发表了系列文章。
研究领域
1. 研究由lncRNA和三维基因组结构所组成的三维转录调控在脑衰老中的作用
2. 研究lncRNA和染色质相互作用在精子发生过程中的转录调控作用
3. 研究减数分裂相关特定基因的功能及其分子机制
近期论文
查看导师最新文章
（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）
1. Luo Z.*, Hu T. *, Jiang H., Wang R., Xu Q., Zhang S., Cao J., Song X.#. Rearrangement of macronucleus chromosomes correspond to TAD-like structures of micronucleus chromosomes in Tetrahymena thermophila. Genome Research. 2020. Mar 12. doi: 10.1101/gr.241687.118. #Corresponding author.
2. Cheng Q.*, Ouyang X.*, Zhang R.*, Zhu L., Song X.#. Senescence-associated genes and non-coding RNAs function in pancreatic cancer progression. RNA Biology. 2020. Jan 30: 1-14. #Corresponding author.
3. Cao J., Jiang H.*, Zhang R.*, Ghanam AR.*, Xia H., Zhu Y., Yang Z., Song X.#. Epigenomic profiling identifies the role of Nr5a2 and CYP1B1 in hepatocellular carcinoma stemness maintenance. Science Bulletin. 2019. 64: 1132-1135. #Corresponding author.
4. Ghanam AR., Cao J., Ouyang X., and Song X.#. New insights into chronological mobility of retrotransposable elements in vivo. Oxidative Medicine and Cellular Longevity. 2019. 2818415. eCollection 2019. #Corresponding author.
5. Wang F.*, Ren D.*, Liang X.*, Ke S., Zhang B., Hu B.#, Song X.#, Wang X.#. A long noncoding RNA cluster-based genomic locus maintains proper development and visual function. Nucleic Acids Research. 2019, 47(12): 6315-6329. #Corresponding author.
6. Mamun M.Al., Mannoor K., Cao J., Qadri F., Song X.#. SOX2 in cancer stemness: Tumor malignancy and therapeutic potentials. Journal of Molecular Cell Biology. 2018. doi: 10.1093/jmcb/mjy080. #Corresponding author.
7. Ghanam AR., Xu Q., Ke Sh., Azhar M., Cheng Q., Song X.#. Shining the light on senescence associated lncRNAs. Aging & Disease. 2017, 1; 8(2):149-161. #Corresponding author.
8. Xu Q., Wang R., Ghanam AR., Yan G., Miao W., Song X.#. The key role of CYC2 during meiosis in Tetrahymena thermophila. Protein & Cell. 2016, 7(4):236-49. #Corresponding author.
9. Cao J., Luo Z., Cheng Q., Xu Q., Zhang Y., Wang F., Wu Y., Song X.#. Three-dimensional regulation of transcription. Protein & Cell. 2015, 6(4):241-53. #Corresponding author.
10. Song X., Bowen J., Miao W., Liu Y., and Gorovsky MA.#. The nonhistone, N-terminal tail of an essential, chimeric H2A variant regulates mitotic H3-S10 dephosphorylation. Genes & Development. 2012, 26(6):615-29.
11. Song X.*, Wang X.*, Arai S. and Kurokawa R.#. Promoter-associated noncoding RNA from the CCND1 promoter. Methods in Molecular Biology. 2012, 809:609-22. *Co-first author.
12. Harismendy O.*, Notani D.*, Song X., Rahim NG., Tanasa B., Heintzman N., Ren B., Fu XD., Topol EJ., Rosenfeld MG#, and Frazer KA#. 9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. Nature. 2011, 470(7333):264-8. *Co-first author.
13. Wang X.* and Song X.*, Glass CK., and Rosenfeld MG#. The Long Arm of Long Noncoding RNAs: Roles as Sensors Regulating Gene Transcriptional Programs. Cold Spring Harb Perspect Biol. 2011 3(1):a003756. *Co-first author. Collected in《The RNA World》IV.
14. Wang X., Arai S.*, Song X.*, Reichart D., Du K., Pascual G., Tempst P., Rosenfeld MG.#, Glass CK.#, and Kurokawa R.#. Induced ncRNAs allosterically modify RNA binding proteins in cis to inhibit transcription. Nature. 2008, 454(7200):126-30.
15. Song, X.*, Gjoneska E.*, Ren Q.*, Taverna SD., Allis C.D., and Gorovsky MA.#. Phosphorylation of the SQ H2A.X motif is required for proper meiosis and mitosis in Tetrahymena thermophila. Mol Cell Biol. 2007, 27(7):2648-60. *Co-first author.
16. Song X. and Gorovsky MA.#. Unphosphorylated H1 is enriched in a specific region of the promoter when CDC2 is down-regulated during starvation. Mol Cell Biol. 2007, 27(5):1925-33.
17. Shang Y., Song X., Bowen J., Corstanje R., Gao Y., Gaertig J., and Gorovsky MA.#. A robust inducible-repressible promoter greatly facilitates gene knockouts, conditional expression, and overexpression of homologous and heterologous genes in Tetrahymena thermophila. PNAS. 2002, 99(6):3734-9.
京公网安备 11010802027423号