75. Xiaoluan Lu, Zhongshan He, Xiao Xiao, Xuelian Wei, Xiangrong Song*, Shiyong Zhang*, Natural Antioxidant-Based Nanodrug for Atherosclerosis Treatment, Small, 2023, 2303459.
74. Mengqi Jia, Ruilin Lu, Caikun Liu, Xiaodong Zhou, Pengfei Li, Shiyong Zhang*, In Situ Implantation of Chitosan Oligosaccharide-Doped Lipoic Acid Hydrogel Breaks the “Vicious Cycle” of Inflammation and Residual Tumor Cell for Postoperative Skin Cancer Therapy, ACS Appl. Mater. Interfaces, 2023, 15, 27, 32824–32838.
73. Rong Cui, Bing Li, Chunyan Liao, Shiyong Zhang*, Copper-mediated chemodynamic therapy with ultra-low copper consumption by doping cupric ion on cross-linked (R)-(+)-lipoic acid nanoparticles, Regenerative Biomaterials, 2023, 10, rbad021.
72. Jiangbing Tan, Pei Jing, Xiao Xiao, Yulong Liao, Chunyan Liao, Shiyong Zhang*, Cross-linked lipoic acid nanocapsules serve as H2O2 amplifier to strengthen the H2O2-sensitive prodrug activation, Science China Chemistry, 2023, 66(9), 2654-2663.
71. Huangjin Lai, Xiao Wu, Juan Tan, Xiaodong Zhou, Chunyan Liao, Shiyong Zhang*, Regulation of Tumor Lactate Metabolism by Targeting Glycolysis and Mitochondrial OXPHOS for Tumor Metastasis Inhibition, Ind. Eng. Chem. Res., 2023, 62, 27, 10290–10300.
70. Yuhong Zhu, Pengfei Li, Caikun Liu, Mengqi Jia, Yadong Luo, Dengfeng He, Chunyan Liao, Shiyong Zhang*, Azobenzene quaternary ammonium salt for photo-controlled and reusable disinfection without drug resistance, Chinese Chemical Letters, 2023, 34, 107543.
69. Xiao Wu, Yifeng Tan, Jing Zhang, Rong Cui, Chunyan Liao, Shiyong Zhang*, Nanodrug constructed using dietary antioxidants for immunotherapy of metastatic tumors, J. Mater. Chem. B, 2023, 11, 2916-2926.
68. Juan Tan, Xueying Zhou, Shiyong Zhang*, Iron-doped cross-linked lipoic acid nano-aggregates for ferroptosis-mediated cancer treatment, Acta Biomaterialia, 2023, 159, 289–299.
67. Caikun Liu, Ruilin Lu, Mengqi Jia, Xiao Xiao, Yun Chen, Pengfei Li, Shiyong Zhang*, Biological Glue from Only Lipoic Acid for Scarless Wound Healing by Anti-inflammation and TGF-β Regulation, Chem. Mater., 2023, 35, 6, 2588–2599.
66. Pei Jing, Yuling Luo, Yun Chen, Jiangbing Tan, Chunyan Liao, Shiyong Zhang*, Aspirin-Loaded Cross-Linked Lipoic Acid Nanodrug Prevents Postoperative Tumor Recurrence by Residual Cancer Cell Killing and Inflammatory Microenvironment Improvement, Bioconjugate Chem., 2023, 34, 2, 366–376.
65. Xuelian Wei, Caikun Liu, Zhengxiang Gu, Kui Luo, Junxiao Yang*, Shiyong Zhang*, Multifunctional Poly(acrylic acid)/Chitosan nanoparticle network hydrogels with tunable mechanics, Applied Materials Today, 2022, 29, 101696.
64. Yadong Luo, Xiaodong Zhou, Caikun Liu, Ruilin Lu, Mengqi Jia, Pengfei Li, Shiyong Zhang*, Scavenging ROS and inflammation produced during treatment to enhance the wound repair efficacy of photothermal injectable hydrogel, Biomaterials Advances, 2022, 141, 213096.
63. Chunyan Liao, Xiang Wang, Xueying Zhou, Dequan Wang, Ziyin Zhang, Yan Liu, Xiao Wu, Ying Chen, Yifeng Tan, Xin Dai, Pei Jing, Jie Pang, Xiao Xiao, Jie Liu, Xiaoming Liao, Shiyong Zhang*, Dietary Antioxidant-Constructed Nanodrugs Can High-Efficiently Kill Cancer Cells while Protecting Noncancer Cells, ACS Appl. Mater. Interfaces, 2022, 14(44), 49508–49520.
62. Liangkui Hu, Bing Li, Yulong Liao, Simeng Wang, Peng Hou, Yangyang Cheng*, Shiyong Zhang*, Nitroreductase-induced bioorthogonal ligation for prodrug activation: A traceless strategy for cancer-specific imaging and therapy, Bioorganic Chemistry, 2022, 129, 106167.
61. Yun Chen, Rong Cui, Yadong Luo, Pei Jing, Caikun Liu, Bing Li, Xiaoming Liao, Shiyong Zhang*, Harnessing Self-Cyclic Cascade System for Reactive Oxygen Species-Boosted Photothermal Immunotherapy, Chem. Mater., 2022, 34(18), 8219–8229.
60. Ying Chen, Xiaoming Liao, Pei Jing, Liangkui Hu, Zengqiu Yang, Yongchao Yao, Chunyan Liao, Shiyong Zhang*, Linoleic Acid–Glucosamine Hybrid for Endogenous Iron-Activated Ferroptosis Therapy in High-Grade Serous Ovarian Cancer, Mol. Pharmaceutics, 2022, 19(9), 3187–3198.
59. Xueying Zhou, Xin Dai, Juan Tan, Xiao Wu, Xiaodong Zhou, Chunyan Liao, Shiyong Zhang*, Quaternary Ammonium Salts Anchored on Cross-Linked (R)-(+)-Lipoic Acid Nanoparticles for Drug-Resistant Tumor Therapy, ACS Appl. Mater. Interfaces, 2021, 13(48), 56850–56857.
58. Yongchao Yao, Yunlong Yu, Xiaohui Wan, Daoping Yan, Ying Chen, Jianbin Luo, G. Julius Vancso, Shiyong Zhang*, Azobenzene-Based Cross-Linked Small-Molecule Vesicles for Precise Oxidative Damage Treatments Featuring Controlled and Prompt Molecular Release, Chem. Mater., 2021, 33(18), 7357-7366.
57. Pengfei Li, Wenqi She, Yadong Luo, Dengfeng He, Jiali Chen, Ning Ning, Yunlong Yu*, Sissi de Beer, Shiyong Zhang, One-pot, self-catalyzed synthesis of self-adherent hydrogels for photo-thermal, antimicrobial wound treatment, J. Mater. Chem. B, 2021, 9, 159-169.
56. Liang Wang, Pei Jing, Juan Tan, Chunyan Liao, Yun Chen, Yunlong Yu, Shiyong Zhang, “One-stitch” bioorthogonal prodrug activation based on cross-linked lipoic acid nanocapsules, Biomaterials, 2021, 273, 120823.
55. Yao, Y., Dai, X., Tan, Y., Chen, Y., Liao, C., Yang, T., Chen, Y., Yu, Y., Zhang, S., Deep Drug Penetration of Nanodrug Aggregates at Tumor Tissues by Fast Extracellular Drug Release. Adv. Healthcare Mater., 2021, 10, 2001430.
54. Dengfeng He, Yifeng Tan, Pengfei Li, Yadong Luo, Yuhong Zhu, Yunlong Yu, Jiali Chen, Ning Ning, Shiyong Zhang, Surface charge-convertible quaternary ammonium salt-based micelles for in vivo infection therapy. Chin. Chem. Lett., 2021, 32, 1743-1746.
53. Fan Yang, Yun Chen, Jing Zhang, Chunyan Liao and Shiyong Zhang, Cross-linked (R)-(+)-lipoic acid nanoparticles with prodrug loading for synergistic cancer therapy. J. Mater. Chem. B, 2021,9, 1583-1591.
52. He, D., Yu, Y., Liu, F., Yao, Y., Li, P., Chen, J., & Zhang, S*. Quaternary ammonium salt-based cross-linked micelle templated synthesis of highly active silver nanocomposite for synergistic anti-biofilm application. Chem. Eng. J., 2020, 382, 122976.
51. Yun Chen, Jiangbing Tan, Qian Zhang, Tuo Xin, Yunlong Yu, Yu Nie, and Shiyong Zhang*. Artificial Organelles Based on Cross-Linked Zwitterionic Vesicles. Nano Lett., 2020, 20, 6548-6555.
50. Yao, Y., Xu, D., Zhu, Y., Dai, X., Yu, Y., Luo, J., & Zhang, S*. Dandelion flower-like micelles. Chem. Sci., 2020, 11, 757-762.
49. Zhang, Q., Chen, Y., Lu, R., Yao, Y., Li, C., Yu, Y., & Zhang, S*. Cross-linked small-molecule capsules with excitation wavelength-dependent photoluminescence and high loading capacity: design, synthesis and application in imaging-guided drug delivery. J. Mater. Chem. B, 2020, 8, 2719-2725.
48. Liang J, Liu F, Zou J, Xu HHK, Han Q, Wang Z, Li B, Yang B, Ren B, Li M, Peng X, Li J, Zhang S*, Zhou X, Cheng L. pH-Responsive Antibacterial Resin Adhesives for Secondary Caries Inhibition. J Dent Res., 2020, 99, 1368-1376. (§These authors contributed equally to this work).
47. Pengfei Li, Zhichao Ding, Yue Yin, Xiaojie Yu, Yucheng Yuan, Maria Brió Pérez, Sissi de Beer, G. Julius Vancso, Yunlong Yu, Shiyong Zhang. Cu2+-doping of polyanionic brushes: A facile route to prepare implant coatings with both antifouling and antibacterial properties. Eur. Polym. J., 2020, 134, 109845.
46. Yun Chen, Qian Zhang, Maureen Willis, Yongchao Yao, Jingsheng Huang, Bingji Wang, Yunlong Yu, and Shiyong Zhang*. A Simple Method to Supply Organic Nanoparticles with Excitation-Wavelength-Dependent Photoluminescence. Langmuir., 2020, 36, 3193-3200.
45. Chunyan Liao, Xin Dai, Ying Chen, Jie Liu, Yongchao Yao, and Shiyong Zhang*. “Biogenic (R)-(+)-Lipoic Acid Only Constructed Cross-Linked Vesicles with Synergistic Anticancer Potency”. Adv. Funct. Mater., 2019, 17, 1806567.
44. Yu Y, Li P, Zhu C, Ning N, Zhang S*, Vancso GJ. Multifunctional and Recyclable Photothermally Responsive Cryogels as Efficient Platforms for Wound Healing. Adv. Funct. Mater., 2019, 29, 1904402.
43. Chuanqi Li, Jing Zhang, Shiyong Zhang* and Yan Zhao. Efficient Light Harvesting Systems with Tunable Emission through Controlled Precipitation in Confined Nanospace. Angew. Chem. Int. Ed., 2019, 58, 1643-1647. (Back cover)
42. Chen, Y., Yao, Y., Zhou, X., Liao, C., Dai, X., Liu, J., ... & Zhang, S*. Cascade-Reaction-Based Nanodrug for Combined Chemo Starvation Chemodynamic Therapy against Multidrug-Resistant Tumors. ACS Appl. Mater. Interfaces, 2019, 11, 46112-46123.
41. Yu, Y., Chen, Y., Huang, J., Wang, L., Gu, Z., & Zhang, S*. Redox-responsive tetraphenylethylene-buried crosslinked vesicles for enhanced drug loading and efficient drug delivery monitoring. J. Mater. Chem. B, 2019, 7, 7540-7547.
40. Xin Dai, Xueying Zhou, Chunyan Liao, Yongchao Yao, Yunlong Yu, and Shiyong Zhang*, “A nanodrug to combat cisplatin-resistance by protecting cisplatin with p-sulfonatocalix[4]arene and regulating glutathione S-transferases with loaded 5-fluorouracil”,Chem. Commun., 2019, 55, 7199-7202.
39. Xiang, F., Li, B., Zhao, P., Tan, J., Yu, Y., & Zhang, S*. Copper (I)‐Chelated Cross‐Linked Cyclen Micelles as a Nanocatalyst for Azide‐Alkyne Cycloaddition in Both Water and Cells. Adv. Synth. Catal.,2019. 361, 5057-5062.
38. Fangqin Liu, Dengfeng He, Yunlong Yu, Lei Cheng and Shiyong Zhang*. Quaternary Ammonium Salt-Based Cross-linked Micelles to Combat Biofilm. Bioconjugate Chem., 2019, 30, 541-546.
37. Jing Zhang, Chuanqi Li, Chunyan Liao, Puchen Zhao, Yunlong Yu, and Shiyong Zhang*. Cross-Linked Reverse Vesicle as a General and Effective Vehicle for Hydrophobic Drugs. Langmuir, 2019, 35, 6676-6682.
36. Yongchao Yao#, Ying Chen#, Yong Liu, Yuhong Zhu, Yuanming Liu and Shiyong Zhang*. Facile Transfer of Reverse Micelles from the Organic to the Aqueous Phase for Mimicking Enzyme Catalysis and Imaging-Guided Cancer Therapy. Langmuir, 2019, 35, 5871-5877. (# These authors contributed equally to this work.)
35. Yu, Y., Cirelli, M., Li, P., Ding, Z., Yin, Y., Yuan, Y., ... & Zhang, S*. Enhanced Stability of Poly (3-sulfopropyl methacrylate potassium) Brushes Coated on Artificial Implants in Combatting Bacterial Infections. Ind. Eng. Chem. Res., 2019, 58, 21459-21465.
34. Yongchao Yao, Chuanqi Li, Fangqin Liu, Pengxiang Zhao, Zhongwei Gu and Shiyong Zhang*. Covalent Capture of Supramolecular Species in Aqueous Solution of Water-Miscible Small Organic Molecules. Phys. Chem. Chem. Phys., 2019, 21, 10477-10487.
33. Jingsheng Huang, Liang Wang, Pangxiang Zhao, Fuqing Xiang and Shiyong Zhang*, Nano-Copper Dopped Cross-linked Lipoic Acid Nanoparticles for Morphology-Dependent Intracelluar Catalysis, ACS Catal., 2018, 8, 5941-5946.
32. Bing Li, § Yunlong Yu, § Fuqing Xiang, Shiyong Zhang*, and Zhongwei Gu, Latent Naphthalimide Bearing Water-Soluble Nanoprobes With Catechol-Fe(III) Cores for in Vivo Fluorescence Imaging of Intracellular Thiols. ACS Appl. Mater. Interfaces, 2018, 10, 16282-16290. ( § These authors contributed equally to this work.)
31. Jingsheng Huang, Yun Chen, Pengxiang Zhao, Yunlong Yu, Zhongwei Gu, and Shiyong Zhang*, Co-Solvent Polarity Controlled Self-Assembly of Tetraphenylenylenthylene-Buried Amphiphile for Size-Regulated Tumor Accumulation. Regener. Biomater., 2018, 1-8.
30. JingouLiang, Mingyun Li, Biao Ren, Tianmu Wu, Hockin H.K. Xu, Yong Liu, Xian Peng, Ge Yang, Michael D. Weir, ShiyongZhang*, Lei Cheng*, Xuedong Zhou*, The anti-caries effects of dental adhesive resin influenced by the position of functional group in quaternary ammonium monomer. Dent. Mater., 2018, 34, 400-411.
29. Jianyue Feng, Qiang Luo, Yun Chen, Bing Li, Kui Luo, Jingbo Lan*, Yunlong Yu and Shiyong Zhang*, DOTA Functionalized Cross-Linked Small-Molecule Micelles for Theranostics Combining Magnetic Resonance Imaging and Chemotherapy, Bioconjugate Chem., 2018, 29, 3402-3410.
28. Fang Wu, Dengfeng He, Lei Chen, Fangqin Liu, Haolong Huang, Jiangshan Dai, Shiyong Zhang*, and Jingsong You, Antibacterial Coordination Polymer Hydrogels Consisted of Silver(I)-PEGylated Bisimidazolylbenzyl Alcohol. RSC Adv., 2018, 8, 20829-20835.
27. Yun Chen, Jingsheng Huang, Shiyong Zhang*, and Zhongwei Gu, Superamphiphile Based Cross-Linked Small-Molecule Micelles for pH-Triggered Release of Anticancer Drugs. Chem. Mater., 2017, 29, 3083–3091.
26. Jingsheng Huang, Yunlong Yu, Liang Wang, Xingjian Wang, Zhongwei Gu, and Shiyong Zhang*, Tetraphenylethylene-Induced Cross-Linked Vesicles with Tunable Luminescence and Controllable Stability. ACS Appl. Mater. Interfaces, 2017, 9, 29030–29037.
25. Jie Pang, Fang Wu, Chunyan Liao, Yongchao Yao, Zhongwei Gu and Shiyong Zhang*, Terminal Acetylated/Acrylated Poly(ethyleneglycol) Fabricated Drug Carriers: Design, Synthesis, and Biological Evaluation. Biomacromolecules, 2017, 18 , 1956-1964.
24. Yong Liu, Ying Chen, Yongchao Yao, Kui Luo, Shiyong Zhang*, and Zhongwei Gu, Confined Pool-Buried Water-Soluble Nanoparticles from Reverse Micelles. Langmuir, 2017, 33, 5275-5282.
23. Jingsheng Huang, Fang Wu, Yunlong Yu*, Haolong Huang, Shiyong Zhang*, and Jingsong You*, Lipoic Acid Based Core Cross-linked Micelles for Multivalent Platform: Design, Synthesis and Application in Bio-imaging and Drug Delivery. Org. Biomol. Chem., 2017, 15, 4798–4802.
22. Ying Chen, Yong Liu, Yongchao Yao, Shiyong Zhang*, and Zhongwei Gu, Reverse micelle-based water-soluble nanoparticles for simultaneous bioimaging and drug delivery. Org. Biomol. Chem., 2017, 15, 3232–3238.
21. Yangyang Yu, Chenlu Lin, Bing Li, Pengxiang Zhao and Shiyong Zhang*, Dendrimer-like core cross-linked micelle stabilized ultra-small gold nanoclusters as robust catalyst for aerobic oxidation of α-hydroxy ketones in water. Green Chem., 2016, 18, 3647-3655. Highlighted by SYNFACTS.
20. Chunyan Liao, Yun Chen, Yongchao Yao, Shiyong Zhang*, Zhongwei Gu, and Xiaoqi Yu, Cross-Linked Small-Molecule Micelle Based Drug Delivery System: Concept, Synthesis, and Biological Evaluation. Chem. Mater., 2016, 28, 7757−7764.
19. Bing Li, Yangyang Yu, Pengxiang Zhao, and Shiyong Zhang*, Triazole-Containing Dendrimer-like Core Cross-Linked Micelles that Stabilize Pd Nanoparticles as Heterogenized Homogeneous Catalysts for Room-Temperature Suzuki–Miyaura Reactions in Water. Chem. - Asian J., 2016, 11, 3550–3556.
18. Chuanqi Li, Shiyong Zhang*, Jie Pang, Yao Wu and Zhongwei Gu*, Facile Fabrication of Robust Organic Counterion-Induced Vesicles: Reversible Thermal Behavior for Optical Temperature Sensor and Synergistic Catalyst upon Removal of Amine. Adv. Funct. Mater., 2015, 25, 3764-3774.
17. Gaocan Li, Shiyong Zhang*, Ningjie Wu, Yangyang Cheng and Jingsong You*, Spontaneous Counterion-Induced Vesicle Formation: Multivalent Binding to Europium(III) for a Wide Range Optical pH Sensor. Adv. Funct. Mater., 2014, 24, 6204–6209.
Prior to joining SCU
16. Shiyong Zhang, Yao Wu, Bin He, Kui Luo and Zhongwei Gu*, Biodegradable Polymeric Nanoparticles Based on Amphiphilic Principle: Construction and Application in Drug Delivery. Sci. China: Chem., 2014, 57, 461-475.
15. Shiyong Zhang and Yan Zhao*, Artificial Metalloenzymes via Encapsulation of Hydrophobic Transition-Metal Catalysts in Surface Cross-Linked Micelles. Chem. Commun., 2012, 48, 9998-10000.
14. Shiyong Zhang and Yan Zhao*, Template Synthesis of Subnanometer Gold Clusters in Interfacially Cross-Linked Reverse Micelles Mediated by Confined Counterions”. Langmuir, 2012, 28, 3606-3613.
13. Shiyong Zhang and Yan Zhao*, Effects of Micelle Properties on the Conformation of Oligocholates and Importance of Rigidity of Foldamers. The Journal of Organic Chemistry, 2012, 77, 556−562.
12. Shiyong Zhang and Yan Zhao*, Flexible Oligocholate Foldamers as Membrane Transporters and Their Guest-Dependent Transport Mechanism. Org. Biomol. Chem., 2012, 260–266.
11. Shiyong Zhang and Yan Zhao*, Oligocholate Foldamers as Carriers for Hydrophilic Molecules across Lipid Bilayers. Chem. - Eur. J., 2011, 17, 12444–12451.
10. Shiyong Zhang and Yan Zhao*, Facile Preparation of Organic Nanoparticles by Interfacial Crosslinking of Reversed Micelles and Template Synthesis of Subnanometer Au-Pt Nanoparticles, ACS Nano, 2011, 5, 2637–2646.
9. Shiyong Zhang and Yan Zhao*, Controlled Release from Cleavable Polymerized Liposomes upon Redox and pH Stimulation, Bioconjugate Chem., 2011, 22, 523–528.
8. Shiyong Zhang and Yan Zhao*, Rapid Release of Entrapped Contents from Multi-Functionalizable, Surface Crosslinked Micelles upon Different Stimulation, J. Am. Chem. Soc., 2010, 132, 10642–10644.
7. Shiyong Zhang and Yan Zhao*, Facile Synthesis of Multivalent Water-Soluble Organic Nanoparticles via “Surface-Clicking” of Alkynylated Surfactant Micelles, Macromolecules, 2010, 43, 4020–4022.
6. Shiyong Zhang, Shuaijun Yang, Jingbo Lan, Yurong Tang, Ying Xue and Jingsong You*, Ultrasound-Induced Switching of Sheet-like Coordination Polymer Microparticles to Nanotubes Capable of Gelating Solvents, J. Am. Chem. Soc., 2009, 131, 1689–1691.
5. Shiyong Zhang, Yurong Tang, Ying Su, Jingbo Lan, Rugang Xie and Jingsong You*, Discrete metallocyclic complexes based on rigid pyrazole-containing ligands as building blocks to construct inorganic-organic supramolecular assemblies through the second interactions, Inorg. Chim. Acta, 2009, 362, 1511–1518.
4. Shiyong Zhang, Yurong Tang, Zhihua Mao, Mingliang Li, Jingbo Lan and Xiaoyu Su, 1,4-bis(1-Imidazolyl)benzene terephthalic acid (1/1)”, Acta Crystallogr., Sect. E: Struct. Rep., 2009, 65, o26.
3. Shiyong Zhang, Shengyong Yang, Jingbo Lan, Shuaijun Yang and Jingsong You*, Helical nonracemic tubular coordination polymer gelators from simple achiral molecules, Chem. Commun., 2008, 6170–6172.
2. Shiyong Zhang, Jingbo Lan, Zhihua Mao, Rugang Xie and Jingsong You*, Crystal Water of Cadmium Acetate-Dependent Formation of One-Dimensional Channel Structure Based on 4,4′-bis(1-Imidazolyl)biphenyl, Cryst. Growth Des., 2008, 9, 3134–3136.
1. Shi-Yong Zhang, Jing-Bo Lan, Xiao-Yu Su, Sheng-Jin Guo, Li Chen, Jing-Song You*, Ru-Gang Xie*, Aerobic oxidative coupling of 2-naphthols by simple copper salts: a highly efficient catalytic system in the absence of ligand or carrier, J. Chem. Res., 2005, 418–419.
